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Neurological Disease

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Cat. No. Product Name Field of Application Chemical Structure
DC12267 Verdiperstat (AZD3241) Featured Verdiperstat is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and is used in the research of neurodegenerative brain disorders.
DC4173 VX-745 Featured VX-745 is a potent and selective inhibitor of p38α MAPK and p38β MAPK with IC50 of 10 nM and 220 nM, respectively.
DC9498 Xanomeline (oxalate) Xanomeline(LY246708) is a selective M1 muscarinic receptor agonist.
DCAPI1039 Ziprasidone HCl Ziprasidone HCl
DC11075 Amelparib
DC10475 Grapiprant Featured Grapiprant is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2)
DC5080 Belnacasan (VX-765) Featured VX-765 is a novel Caspase-1 inhibitor with an IC 50 of 0.8nM being investigated for the treatment of epilepsy, currently being developed by Vertex.

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