| DC9260 |
Eptapirone
Featured
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Eptapirone (F-11,440) is a very potent and highly selective 5-HT1A receptor full agonist of the azapirone family. |
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| DCAPI1535 |
Etodolac |
Etodolac is a Cox-2 inhibitor with anti-inflammatory and analgesic activity. Etodolac is shown to inhibit growth and PCNA expression and induce cell cycle arrest in human hepatocellular carcinoma cell lines, in addition to suppressing the occurrence of ab |
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| DC4239 |
Flupirtine maleate |
Flupirtine maleateis a non-opioid, centrally acting analgesia, muscle relaxation and neuroprotection. Currently under a clinical trial (recruiting phase) as a treatment for Multiple Sclerosis and has been used as an analgesic. |
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| DCAPI1206 |
Flurbiprofen (Ansaid) |
Flurbiprofen (Ansaid) |
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| DC7014 |
GPI-1046 |
For the detailed information of GPI-1046, the solubility of GPI-1046 in water, the solubility of GPI-1046 in DMSO, the solubility of GPI-1046 in PBS buffer, the animal experiment (test) of GPI-1046, the cell expriment (test) of GPI-1046, the in vivo, in vitro and clinical trial test of GPI-1046, the EC50, IC50,and Affinity of GPI-1046, Please contact DC Chemicals.. |
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| DC7016 |
JNJ40411813
Featured
|
For the detailed information of JNJ40411813, the solubility of JNJ40411813 in water, the solubility of JNJ40411813 in DMSO, the solubility of JNJ40411813 in PBS buffer, the animal experiment (test) of JNJ40411813, the cell expriment (test) of JNJ40411813, the in vivo, in vitro and clinical trial test of JNJ40411813, the EC50, IC50,and Affinity of JNJ40411813, Please contact DC Chemicals.. |
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| DC10490 |
GIBH-130
Featured
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GIBH-130 is a novel inhibitor of neuroinflammation effective in Alzheimer’s disease models. |
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| DC7419 |
GNE-7915
Featured
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GNE-7915 is a highly potent, selective, and brain-penetrable LRRK2 small molecule inhibitor with IC50 of 9 nM in cellular LRRK2 assay; > 100 fold selectivity against a panel of 187 kianses(Ki). |
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| DC11090 |
GR3027
Featured
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GR3027 (Golexanolone) is a GABA-A receptor modulating steroid antagonist that selectively antagonizes the enhanced activation of GABAA receptors by neurosteroids such as allopregnanolone and THDOC. |
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| DC5061 |
GYKI 52466 dihydrochloride |
GYKI 52466 dihydrochloride is a selective non-competitive AMPA receptor antagonist (IC50 values are 10-20, ~ 450 and >> 50 μM for AMPA- , kainate- and NMDA-induced responses respectively). Skeletal muscle relaxant and orally-active anticonvulsant. |
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| DC12493 |
HT-2157(SNAP37889)
Featured
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HT-2157 (SNAP 37889) is a selective, high-affinity, competitive antagonists of galanin-3 receptor (Gal3). |
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| DC9329 |
(±)-Huperzine A |
Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD). |
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| DC8965 |
Ibuprofen |
Ibuprofen (Motrin) is an anti-inflammatory inhibitor targeting COX-1 and COX-2, of which is used for pain relief, fever reduction and for reducing swelling. |
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| DCAPI1055 |
Iloperidone (Fanapt) |
Iloperidone (Fanapt) |
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| DC4137 |
Indiplon
Featured
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Indiplon is a novel sedative-hypnotic recently approved for the treatment of insomnia. |
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| DC8379 |
JH-II-127
Featured
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JH-II-127 is a highly potent, selective, and brain penetrant LRRK2 inhibitor. |
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| DC11115 |
JNJ-26489112 |
JNJ-26489112 (JNJ26489112) is a broad-spectrum anticonvulsant that displays activity in rodents against audiogenic, electrically-induced, and chemically-induced seizures. |
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| DC9662 |
JNJ-42165279
Featured
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JNJ-42165279 is a potent and selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH), with an IC50 of 70nM. |
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| DC12271 |
JNJ-54175446
Featured
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JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively. |
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| DC11080 |
JPI-289 |
JPI-289 (JPI289) is a novel potent, water soluble PARP-1 inhibitor with IC50 of 18.5 nM, inhibits cellular PAR formation with IC50 of 10.7 nM. |
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| DC8159 |
L-701,324
Featured
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L-701,324 is a selective antagonist at the glycine site of the NMDA receptor, counteracts haloperidol-induced muscle rigidity in rats. |
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| DC8797 |
Lacosamide
Featured
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Lacosamide (Vimpat; Erlosamide) is a medication developed for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. |
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| DC8173 |
Lemborexant(E2006)
Featured
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Lemborexant (E-2006) is a dual antagonist of the orexin OX1 and OX2 receptors which is under development for treatment of insomnia. |
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| DC10892 |
LMI070 (NVS-SM1)
Featured
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LMI070 (NVS-SM1) is a highly potent, selective and orally active small molecule SMN2 splicing modulator. |
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| DC8642 |
Lorediplon
Featured
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Lorediplon is a new GABAA modulator Drug for treatment of insomnia. |
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| DC11422 |
Lumateperone Tosylate
Featured
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Lumateperone Tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a SERT blocker (Ki = 61 nM). |
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| DC5180 |
LY2811376
Featured
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LY2811376 is the first orally available non-peptidicβ-secretase(BACE1) inhibitor with IC50 of 239 nM-249 nM. |
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| DC5053 |
LY2886721
Featured
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LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease. |
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| DC11323 |
LY354740 |
LY354740 is an agonist of the group II metabotropic glutamate receptor (mGluR) subtypes mGluR2 and mGluR3 (Kis = 99 and 94 nM, respectively). |
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| DC7192 |
LY-404039
Featured
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LY404039 is an inhibitor for mGluR1(Ki=149 nM) and mGluR2(Ki= 92 nM), which can also inhibit dopamine receptor. |
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