DC8970 |
Pramipexole Base |
Pramipexole is a dopamine agonist of the non-ergoline class indicated for treating Parkinson's disease (PD) and restless legs syndrome (RLS). |
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DC3151 |
Pramipexole dihydrochloride |
Pramipexole is a partial/full D2S, D2L, D3, D4, receptor agonist with a Ki of 3.9, 2.2, 0.5, 5.1 nM. |
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DCAPI1473 |
Pregabalin
Featured
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Pregabalin |
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DC9513 |
Radafaxine (hydrochloride)
Featured
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Radafaxine Hcl(BW-306U; GW-353162A) is a potent metabolite of bupropion; selective for inhibiting the reuptake of norepinephrine over dopamine; DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulat |
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DC8175 |
Rapastinel(GLYX-13)
Featured
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Rapastinel(GLYX-13) is a NMDA receptor partial agonist that acts at the glycine site. |
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DC10191 |
RG7800 |
RG7800 a small molecule SMN2 splicing modifier to enter human clinical trials to treat spinal muscular atrophy. |
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DC7268 |
Risperidone(R 64 766) |
Risperidone(R 64 766) is a serotonin 5-HT2 receptor blocker(Ki= 0.16 nM) and a potent dopamine D2 receptor antagonist(Ki= 1.4 nM). |
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DCAPI1435 |
Rivastigmine tartrate |
Rivastigmine hydrogen tartrate is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer’s type and Parkinson's disease. |
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DC5015 |
Rotigotine Hydrochloride |
Rotigotine is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Rotigotine also has significant affinity for 5-HT1A and adrenergic α2B receptors. Rotigotine exhibits antiparkinsonian acitivity. |
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DC7274 |
S1RA
Featured
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S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM). |
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DC9264 |
S1RA hydrochloride
Featured
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S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM). |
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DC11176 |
S44819 |
S44819 (S 44819, Egis-13529) is a novel potent, competitive, selective antagonist of the α5-GABAAR with Kd of 221 nM, IC50 of 585 nM (α5β2γ2). |
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DC4134 |
Safinamide |
Safinamide (EMD 1195686; FCE 26743) selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A. |
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DC9635 |
SB-705498
Featured
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SB-705498 is a potent, selective and orally bioavailable transient receptor potential vanilloid 1 (TRPV1) receptor antagonist with a pIC50 of 7.1. |
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DC7496 |
Semagacestat
Featured
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Semagacestat (LY450139) is a γ-secretase blocker for Aβ42, Aβ40 and Aβ38 with IC50 of 10.9 nM, 12.1 nM and 12.0 nM, also inhibits Notch signaling with IC50 of 14.1 nM. |
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DC9320 |
Setiptiline (maleate) |
Setiptiline is a serotonin receptor antagonist.
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DC9319 |
Setiptiline |
Setiptiline(Org-8282) is a serotonin receptor antagonist.
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DC11529 |
Solriamfetol hydrochloride
Featured
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Solriamfetol hydrochloride (JZP-110, R-228060, ADX-N05, YKP-10A) is a norepinephrine-dopamine reuptake inhibitor that inhibits dopamine and norepinephrine transporter with IC50 of 2.9 and 4.4 uM, respectively. |
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DC5017 |
Suvorexant
Featured
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Suvorexant (MK-4305) is a potent, selective, and orally bioavailable antagonist of OX1R and OX2R currently under clinical investigation as a novel therapy for insomnia.Suvorexant is an analytical reference standard categorized as a diazepane sedative.Formulations containing suvorexant show abuse potential similar to zolpidem in recreational polydrug users with a history of sedative and psychedelic drug use.2 Suvorexant is regulated as a Schedule IV compound in the United States. This product is intended for use in analytical forensic applications. |
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DC8308 |
SYM2206 |
SYM2206 is a novel, potent, non-competitive AMPA receptor antagonist (IC50 = 2.8 μM ). |
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DC9842 |
T0901317
Featured
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T0901317 is a potent, high affinity liver X receptor (LXR) agonist (EC50 ~ 50 nM, Kd values are 7 and 22 nM for LXR-α and LXR-β respectively). |
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DC7945 |
TAK-063
Featured
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TAK-063 is a highly potent, selective and orally active PDE10A inhibitor with IC50 of 0.30 nM; >15000-fold selectivity over other PDEs. |
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DC11208 |
TAK-071
Featured
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TAK-071 is a novel, potent and highly selective muscarinic acetylcholine receptor 1 (M1R) positive allosteric modulator. EC50 of TAK-071 M1R agonist activities is 520 nM. |
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DC11485 |
Tolcapone
Featured
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Tolcapone is an orally active catechol-O-methyltransferase (COMT) inhibitor. |
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DC9332 |
Tozadenant |
Tozadenant (SYN-115) is an adenosine A2A receptor antagonist. |
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DC8824 |
Traxoprodil
Featured
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Traxoprodil is an NMDA ε 2 (NR2B) antagonist that has been studied as an alternative to serotonin selective reuptake inhibitors. |
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DC9157 |
Trifluoperazine dihydrochloride |
Trifluoperazine Dihydrochloride is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic. |
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DC9538 |
TRO 19622
Featured
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TRO19622, a small cholesterol-like molecule, is a neuroregenerative and neuroprotective compound.
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DC10217 |
TRx0237 (LMTX) mesylate
Featured
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TRx 0237 (LMTX™) mesylate is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia. |
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DC7335 |
URB-597
Featured
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URB597 is a potent, orally bioavailable FAAH inhibitor with IC50 of 4.6 nM, with no activity on other cannabinoid-related targets. |
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