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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DCC4818 Sniper(brd4)-1 Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Eraser (SNIPER), acting as a a protein degradation inducer of bromodomain-containing protein 4 (BRD4)
DCC4819 Sniper(ch6) Novel fused proteins degrader of the His-tagged CRABP-II and Smad2 in cells
DCC4820 Sniper(crabp)-11 Novel potent degrader of the mitochondrial CRABP-II protein
DCC4821 Sniper(er)-87 Novel potent and selective degrader of the ERα protein
DCC4822 Sniper(pde4)-9 Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Eraser (SNIPER), acting as a a protein degradation inducer of phosphodiesterase-4 (PDE4)
DCC4823 Snri-h05 Novel potent serotonin and noradrenaline reuptake inhibitor (SNRI) with moderate 5-HT2A antagonist activity for anti-depression
DCC4824 sns-oh Inducer of apoptosis in neuroblastoma cells through inhibition of AKT signaling pathway
DCC4825 Snu-bp Novel agonist of PPAR-gamma, inhibiting lipopolysaccharide (LPS)-induced NO production and pro-inflammatory cytokines, potentiating interleukin-4-induced arginase-1 expression, promoting microglial polarization toward to an M2 anti-inflammatory phenotype
DCC4826 Snx2-1-108 Highly selective inhibitor of CDK8 and its isoform CDK19
DCC4827 So1989 Novel macrophage modulator, inhibiting inflammation and M1 polarization of macrophages, restoring the balance between M1-polarized and M2-polarized macrophages in high fat diets (HFD)-induced obese mice resulting in the improvement of adipose inflammation
DCC4828 soblidotin Inhibitor of tubulin polymerization, resulting in cell cycle arrest and induction of apoptosis
DCC4829 Sobuzoxane Orally available active prodrug of ICRF-154, interferring with topoisomerase II activity prior to the formation of intermediate cleavable DNA-enzyme complexes during the catalytic cycle resulting in tumor cell growth inhibition
DCC4830 Sod1-derlin-1 Inhibitor 56-20 Novel potent inhibitor of SOD1-Derlin-1 interaction
DCC4831 Sod1-derlin-1 Inhibitor 56-26 Novel potent inhibitor of SOD1-Derlin-1 interaction
DCC4832 Sodelglitazar PPARdelta receptor agonist
DCC4833 Sodium Dehydrocholate Hepatoprotective and choleretic agent
DCC4834 Sodium Oxybate Narcolepsy agent, being used to treat catalepse and daytime sleepiness in patients with narcolepsy
DCC4835 Solanidine Natural tumor antagonistic steroidal alkaloid, inducing typical cellular apoptotic hallmarks and cell cycle blockage at S-G2/M phase, activating nuclear import of DFF-40 mediated nucleosomal disruption and cell demise
DCC4836 Solimastat Novel oral, broad-spectrum matrix metalloproteinase inhibitor (MMPI), being >10-fold more active than marimastat in inhibiting the processing of cell-bound TNF-alpha
DCC4837 Somapacitan Novel long-acting, reversible albumin-binding growth hormone (GH) derivative for treatment of growth hormone dificiency
DCC4838 Somatoprim Unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue, effectively reducing GH secretion in human GH-secreting pituitary adenomas even in Octreotide non-responsive tumours.
DCC4839 Somcl-668 Novel potent and selective allosteric modulator of sigma-1 receptor
DCC4840 Somcl-863 Novel, selective and orally bioavailable c-Met inhibitor, exhibiting antitumor activity both in vitro and in vivo
DCC4841 Sonedenoson A2A adenosine receptor agonist
DCC4842 Sophoradin Natural analgesic, antipyretic, anti-inflammatory, and anti-tumor agent
DCC4843 Sophorafavanone A Inhibitor of constitutive and inducible STAT3 activation through the activation of SHP-2 tyrosine phosphatase
DCC4844 Sophoraflavanone B Natural inhibitor of the Kv1.3 channels in a concentration-dependent manner
DCC4845 soraphinol A Human norepinephrine transporter blocker
DCC4846 sori-20041 DAT modulator, being unique in affecting substrate uptake without impacting efflux
DCC4847 sori-9804 Novel partial inhibitor of amphetamine-induced dopamine release

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