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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DCC4787 Sm-337 Non-peptidic Smac mimetic, binding to XIAP, cIAP-1 and cIAP-2 proteins with higher affinities in cell growth inhibition in the MDA-MB-231 cell line
DCC4788 Sm4487 Novel potent and selective inhibitor of galactokinase (GALK1)
DCC4789 Sma-12b Novel inhibitor of IL-1
DCC4790 Smac127 Proapoptotic and anti-inflammatory agent, inducing apoptosis by inhibiting apoptosis proteins (IAPs)
DCC4791 Smapp1 Novel activator of PP1, inducing HIV-1 transcription, reactivation of latent HIV-1 in chronically infected cells, and CDK9 phosphorylation
DCC4792 Smart-h Potent inhibitor of microtubule polymerization
DCC4793 Smart-oh Potent inhibitor of microtubule polymerization
DCC4794 Smases D Inhibitor-1 Novel inhibitor of Loxosceles sphingomyelinases D (SMases D)
DCC4795 Smases D Inhibitor-5 Novel inhibitor of Loxosceles sphingomyelinases D (SMases D)
DCC4796 Smcy 5.5 Fluorogenic fluorescent probe for imaging lipid droplets; suitable for use with two-photon microscopy
DCC4797 Smdc818909 Novel Allosteric Inhibitor of p97
DCC4798 Smer10 Novel enhancer of the clearance of mutant aggregate-prone proteins by autophagy in mammalian cell models of Huntington's and Parkinson's disease, independent of rapamycin
DCC4799 S-mgb-234 Bis-tfa Salt Novel strathclyde minor groove binder (S-MGB), curing animal African trypanosomiasis (AAT)
DCC4800 smip001 Novel enhancer of the cyclin-dependent kinase (CDK) inhibitor p27(Kip)
DCC4801 Smip2.1 Novel TLR2 agonist, promoting cross-presentation by mouse and human antigen presenting cells
DCC4802 Smk-17 Novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor
DCC4803 Sml-10-70-1 Selective, direct-acting covalent inhibitor of the K-Ras G12C mutant relative to wild-type Ras
DCC4804 Sml-8-73-1 Novel Active Site Inhibitor of Oncogenic K-Ras G12C
DCC4805 Smn2-stablizer-27 Novel Stablizer of Survival of Motor Neuron 2 (SMN2) , Post-Translationally Stablizing SMN Protein for the Treatment of Spinal Muscular Atrophy (SMA)
DCC4806 Smn-c5 Novel specific splicing enhancer, targeting RNA for a specific splicing correction, recognizing the interface between U1 snRNP and the SMN2 E7 5ʹ SS, promoting the U1-C zinc finger RNA duplex binding activity
DCC4807 Smt022357 Second-generation modulator of utrophin, increasing utrophin expression in skeletal, respiratory and cardiac muscles
DCC4808 Smtp-7 Novel dual inhibitor of thrombolysis and soluble epoxide hydrolase
DCC4809 Smurf1 Inhibitor 1 Novel Smurf1 inhibitor, promoting bone formation in mouse models of distinctive age-related osteoporosis
DCC4811 Sn16713 Selective ligand of GC-rich sequences in DNA
DCC4812 Sn-28049 Novel potent DNA-binding topoisomerase II-directed antitumor agent.
DCC4813 Sn34037 Novel specific inhibitor of Aldo-keto reductase 1C3 (AKR1C3, EC 1.1.1.188)
DCC4814 Sn-38 Prodrug 3c Novel Bioorthogonal Prodrug of SN-38 with Fast Reaction Kinetics and High Releasing Efficiency In Vivo
DCC4815 Snap-398299 Potent and selective GAL3 antagonist
DCC4816 Snap-5089 Highly selective alpha1A-adrenoceptor antagonist
DCC4817 Sniper(abl)-38 Specific and Nongenetic IAP-dependent Protein Eraser (SNIPER), acting as a protein degradation inducer of oncogenic BCR-ABL protein

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