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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DCC5267 Tug-2015 Novel allosteric modulator of free fatty acid receptor 3 (FFA3, previously GPR41)
DCC5268 Tulobuterol Hydrochloride Long-acting beta2-adrenergic receptor agonist
DCC5269 tumor Metastasis Blocker 5k Novel Inhibitor of Metastatic Cancer Cell Migration and Invasion
DCC5270 Tunicamycin Antibiotic, inhibiting the first step in the N-linked glycosylation in eukaryotes and inducing ER stress to activate the unfolded protein response (UPR)
DCC5271 Turneroic Acid Inhibitor of bacterial biofilm formation in Staphylococcus epidermidis
DCC5272 Tutuilamide A Natural potent porcine pancreatic elastase (PPE) inhibitor
DCC5273 Txa1 Hydrochloride Novel anticancer agent, affecting steroid biosynthesis, increasing RagD expression, and causing abnormal cellular cholesterol localization
DCC5274 Txa-709 Novel disruptor of the bacterial protein, FtsZ
DCC5275 Ty-51469 Chymase inhibitor, preventing the development and progression of non-alcoholic steatohepatitis, improving vascular dysfunction and survival in stroke-prone spontaneously hypertensive rats
DCC5276 Tyk2 Jh2-in-48 Novel highly potent and selective TYK2 JH2 inhibitor, providing robust inhibition in a mouse IL-12-induced IFNγ pharmacodynamic model as well as efficacy in an IL-23 and IL-12-dependent mouse colitis model
DCC5277 Bll5 Maleate First-in-class selective PRMT5 inhibitor, blocking EBV-driven B lymphocyte transformation and survival while leaving normal B cells unaffected
DCC5278 Tyr(po(nme2)2 Stable analog of phosphotyrosine (pTyr)
DCC5279 Tyrosinase Inhibitor Thio-2 Novel competitive inhibitor of tyrosinase enzyme
DCC5280 U-101958 Maleate [224170-09-6] Potent and selective dopamine D4 receptor antagonist
DCC5281 Ua62784 Novel potent inhibitor of microtubule polymerization, binding directly to tubulin α/β heterodimers via the colchicine-binding site, perturbing mitotic spindles, delaying cells in mitosis and promotes apoptosis
DCC5282 Uawj172 Novel potent and broad-spectrum antiviral agent against multiple strains of EV-D68, EV-A71, and CVB3, targeting the viral protein 2C
DCC5283 Ubp512 Selective modulator of NMDA_receptor>NMDA receptors, potentiates responses at GluN1/GluN2A
DCC5284 Ubp618 Novel pan-inhibitor of GluN1/GluN2 receptors
DCC5285 Ubp646 Novel pan potentiator of GluN1/GluN2 receptors
DCC5286 Ubp684 Novel NMDAR positive allosteric modulator (PAM), robustly potentiating responses at all GluN1/GluN2 subtypes and at neuronal NMDARs
DCC5287 Ubtr008295a Novel Antagonist of the USP5 Zinc Finger Ubiquitin-Binding Domain (USP5 ZnF-UBD)
DCC5288 Ucb-11056 Modulator of cyclic AMP generation, amplifing induced cyclic AMP formation in rat brain tissue; Nootropic
DCC5289 ucb30889 Potent ligand of synaptic vesicle protein 2A (SV2A)
DCC5290 Ucb-6786 Novel inhibitor of TNF signalling by stabilising an asymmetric form of the trimer, displaying a concentration-dependent response curve and selectivity over the TNFR1 extracellular domain and control proteins
DCC5291 Ucb-6876 Novel inhibitor of TNF signalling by stabilising an asymmetric form of the trimer, displaying a concentration-dependent response curve and selectivity over the TNFR1 extracellular domain and control proteins
DCC5292 Ucb-fcrn-303 Novel allosteric modulator of neonatal Fc receptor (FcRn), binding to the extracellular domain of FcRn
DCC5293 uc-ddc-918013 Selective competitive inhibitor of ATX-mediated hydrolysis of the lysophospholipase substrate FS-3
DCC5294 uc-ddc-931126 Selective competitive inhibitor of ATX-mediated hydrolysis of the lysophospholipase substrate FS-3
DCC5295 uc-ddc-966791 Competitive dual inhibitor of the hydrolysis FS-3 and the phosphodiesterase substrate p-nitrophenyl thymidine 5'-monophosphate
DCC5297 Uck2-in-135546734 Novel non-competitive UCK2 inhibitor, suppressing nucleoside salvage in cells both in the presence and absence of DHODH inhibitors

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