Cat. No. | Product name | CAS No. |
DC23524 |
CXCR2-IN-68
CXCR2-IN-68 is a potent, selective, brain penetrant, and orally bioavailable CXCR2 antagonist with pIC50 of 9.0, displays 730-fold selectivity over CXCR1 and >1,900-fold selectivity over all other chemokine receptors. |
1838123-21-9 |
DC20349 |
CXL017
CXL017 is a small molecule that has selective cytotoxicity toward MDR cancer cell lines in vitro, through inhibition of the sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) with IC50 of 15 uM. |
1063714-11-3 |
DC10775 |
Fadraciclib (CYC065)
Featured
CYC065 is an orally bioavailable inhibitor of cyclin dependent kinases 2, 5 and 9 (CDK2/5/9) with potential antineoplastic and chemoprotective activities. |
1070790-89-4 |
DC7325 |
CYC116
Featured
CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM. |
693228-63-6 |
DC26110 |
Cyclapolin 1
Cyclapolin 1 is a potent and selective PLK1 inhibitor that promotes loss of centrosome integrity and microtubule nucleating ability apparently through increased accessibility of protein phosphatases. |
736157-02-1 |
DC26115 |
Cyclapolin 9
Cyclapolin 9 is a potent, selective, and ATP-competitive polo-like kinase PLK1 inhibitor with IC50 of 500 nM.. |
40533-25-3 |
DC10368 |
Cyclo(his-pro)
Cyclo(His-Pro) is a cyclic dipeptide structurally related to tyreotropin-releasing hormone. |
53109-32-3 |
DC20657 |
Cyclocreatine Phosphate
Cyclocreatine Phosphate (AM 285) is an analog of the creatine kinase CKMT1 substrate creatine and inhibitor of the creatine biosynthesis pathway. |
18838-38-5 |
DC20350 |
Cyclopamine tartrate
Cyclopamine tartrate is a natural steroidal alkaloid that inhibits hedgehog (Hh) signaling with IC50 of 46 nM. |
1178510-81-0 |
DC11214 |
Cyclophilin inhibitor C31
Cyclophilin inhibitor C31 (SMCypI C31) is a small-molecule cyclophilin (CypA) inhibitor (SMCypI) with PPIase inhibition IC50 of 0.1 uM, displays anti-HCV activity (HCV Gt1b replicon EC50=0.4 uM) and disrupts the CypA-NS5A interaction. |
|
DC20101 |
Cyclosporin A-Derivative 1 Free base
Cyclosporin A-Derivative 1 (Free base) is a crystalline intermediate derived from the opening of cyclosporin A extracted from patent WO 2013167703 A1. Cyclosporin A is an immunosuppressive agent which can bind to the cyclophilin and inhibit calcineurin. |
286852-20-8 |
DC23630 |
Cyclothiazide
Cyclothiazide (Doburil) is a positive allosteric modulator of the AMPA and kainate receptors that potentiates AMPA-mediated glutamate currents. |
2259-96-3 |
DC20351 |
CYD-1-79
CYD-1-79 is a potent, selective 5-HT2C receptor positive allosteric modulator (PAM), potentiates 5-HT-evoked intracellular calcium release in cells stably expressing the human 5-HT2CR but not the 5-HT2AR cells.. |
1443281-47-7 |
DC23283 |
CYD-2-11
CYD-2-11 is a novel potent, selective Bax agonist that targets the structural pocket proximal to S184 in the C-terminal region of Bax (Ki=34.1 nM). |
1425944-22-4 |
DC12469 |
CYH33
CYH33 (CYH-33) is a novel potent, PI3Kα-selective inhibitor with IC50 of 5.9 nM/598 nM/ 78.7 nM/225 nM aginst class I PI3K isoform α/β/δ/γ, respectively. |
1494684-28-4 |
DC12470 |
CYH33 methanesulfonate
CYH33 (CYH-33) is a novel potent, PI3Kα-selective inhibitor with IC50 of 5.9 nM/598 nM/ 78.7 nM/225 nM aginst class I PI3K isoform α/β/δ/γ, respectively. |
1494684-33-1 |
DC20352 |
CYP11B1-IN-25
CYP11B1-IN-25 is a selective, potent 11β-hydroxylase (CYP11B1) inhibitor with IC50 of 2 nM, displays 14-fold selectivity over CYP11B2. |
2101952-78-5 |
DC5134 |
lexibulin (CYT997)
CYT997 is a potent microtubule polymerization inhibitor with IC50 of 10-100 nM in cancer cell lines. Phase 1/2. |
917111-44-5 |
DC11199 |
CZh226
Featured
CZh226 hydrochloride (CZh-226) is a potent, selective inhibitor of p21-activated kinase 4 (PAK4) with Ki of 9 nM, displays 346-fold selectivity over PAK-1. |
2196199-00-3 |
DC11198 |
CZh226 hydrochloride
CZh226 hydrochloride (CZh-226) is a potent, selective inhibitor of p21-activated kinase 4 (PAK4) with Ki of 9 nM, displays 346-fold selectivity over PAK-1. |
2231440-94-9 |
DC9886 |
D-(+)-Cellobiose
D-(+)-Cellobiose is a substrate of β-glucosidase. |
528-50-7 |
DC12296 |
D-(+)-Trehalose dihydrate (D-Trehalose dihydrate; α,α-Trehalose dihydrate)
Featured
D-(+)-Trehalose dihydrate can be used as a food ingredient and pharmaceutical excipient. |
6138-23-4 |