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Cat. No. Product name CAS No.
DC23524 CXCR2-IN-68

CXCR2-IN-68 is a potent, selective, brain penetrant, and orally bioavailable CXCR2 antagonist with pIC50 of 9.0, displays 730-fold selectivity over CXCR1 and >1,900-fold selectivity over all other chemokine receptors.

1838123-21-9
DC20349 CXL017

CXL017 is a small molecule that has selective cytotoxicity toward MDR cancer cell lines in vitro, through inhibition of the sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) with IC50 of 15 uM.

1063714-11-3
DC10775 Fadraciclib (CYC065) Featured

CYC065 is an orally bioavailable inhibitor of cyclin dependent kinases 2, 5 and 9 (CDK2/5/9) with potential antineoplastic and chemoprotective activities.

1070790-89-4
DC7325 CYC116 Featured

CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM.

693228-63-6
DC26110 Cyclapolin 1

Cyclapolin 1 is a potent and selective PLK1 inhibitor that promotes loss of centrosome integrity and microtubule nucleating ability apparently through increased accessibility of protein phosphatases.

736157-02-1
DC26115 Cyclapolin 9

Cyclapolin 9 is a potent, selective, and ATP-competitive polo-like kinase PLK1 inhibitor with IC50 of 500 nM..

40533-25-3
DC10368 Cyclo(his-pro)

Cyclo(His-Pro) is a cyclic dipeptide structurally related to tyreotropin-releasing hormone.

53109-32-3
DC20657 Cyclocreatine Phosphate

Cyclocreatine Phosphate (AM 285) is an analog of the creatine kinase CKMT1 substrate creatine and inhibitor of the creatine biosynthesis pathway.

18838-38-5
DC20350 Cyclopamine tartrate

Cyclopamine tartrate is a natural steroidal alkaloid that inhibits hedgehog (Hh) signaling with IC50 of 46 nM.

1178510-81-0
DC11214 Cyclophilin inhibitor C31

Cyclophilin inhibitor C31 (SMCypI C31) is a small-molecule cyclophilin (CypA) inhibitor (SMCypI) with PPIase inhibition IC50 of 0.1 uM, displays anti-HCV activity (HCV Gt1b replicon EC50=0.4 uM) and disrupts the CypA-NS5A interaction.

DC20101 Cyclosporin A-Derivative 1 Free base

Cyclosporin A-Derivative 1 (Free base) is a crystalline intermediate derived from the opening of cyclosporin A extracted from patent WO 2013167703 A1. Cyclosporin A is an immunosuppressive agent which can bind to the cyclophilin and inhibit calcineurin.

286852-20-8
DC23630 Cyclothiazide

Cyclothiazide (Doburil) is a positive allosteric modulator of the AMPA and kainate receptors that potentiates AMPA-mediated glutamate currents.

2259-96-3
DC20351 CYD-1-79

CYD-1-79 is a potent, selective 5-HT2C receptor positive allosteric modulator (PAM), potentiates 5-HT-evoked intracellular calcium release in cells stably expressing the human 5-HT2CR but not the 5-HT2AR cells..

1443281-47-7
DC23283 CYD-2-11

CYD-2-11 is a novel potent, selective Bax agonist that targets the structural pocket proximal to S184 in the C-terminal region of Bax (Ki=34.1 nM).

1425944-22-4
DC12469 CYH33

CYH33 (CYH-33) is a novel potent, PI3Kα-selective inhibitor with IC50 of 5.9 nM/598 nM/ 78.7 nM/225 nM aginst class I PI3K isoform α/β/δ/γ, respectively.

1494684-28-4
DC12470 CYH33 methanesulfonate

CYH33 (CYH-33) is a novel potent, PI3Kα-selective inhibitor with IC50 of 5.9 nM/598 nM/ 78.7 nM/225 nM aginst class I PI3K isoform α/β/δ/γ, respectively.

1494684-33-1
DC20352 CYP11B1-IN-25

CYP11B1-IN-25 is a selective, potent 11β-hydroxylase (CYP11B1) inhibitor with IC50 of 2 nM, displays 14-fold selectivity over CYP11B2.

2101952-78-5
DC5134 lexibulin (CYT997)

CYT997 is a potent microtubule polymerization inhibitor with IC50 of 10-100 nM in cancer cell lines. Phase 1/2.

917111-44-5
DC11199 CZh226 Featured

CZh226 hydrochloride (CZh-226) is a potent, selective inhibitor of p21-activated kinase 4 (PAK4) with Ki of 9 nM, displays 346-fold selectivity over PAK-1.

2196199-00-3
DC11198 CZh226 hydrochloride

CZh226 hydrochloride (CZh-226) is a potent, selective inhibitor of p21-activated kinase 4 (PAK4) with Ki of 9 nM, displays 346-fold selectivity over PAK-1.

2231440-94-9
DC9886 D-(+)-Cellobiose

D-(+)-Cellobiose is a substrate of β-glucosidase.

528-50-7
DC12296 D-(+)-Trehalose dihydrate (D-Trehalose dihydrate; α,α-Trehalose dihydrate) Featured

D-(+)-Trehalose dihydrate can be used as a food ingredient and pharmaceutical excipient.

6138-23-4
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