Novel selective BET BD1 inhibitor with preferred binding to of BRD4 BD1

Novel potent inhibitor of BRD4 BD2

Novel potent BRD4 D1 inhibitor with over 500-fold selectivity against BRD2 D1 and BRD4 D2 via ITC

Negative control in HDAC1/2/3/8 assays

Novel HDAC8 inhibitor

Novel Mitochondrial Content Inducer

Novel dihydroorotate dehydrogenase (DHODH) inhibitor

Novel multistage antimalarial inhibitor for single-dose treatment of malaria in mouse models

Novel specific inhibitor of the hypomorph growth

Novel inhibitor of dihydroorotate dehydrogenase (DHODH), showing in vitro activity against multidrug-resistant blood-stage parasites

Novel specific inhibitor of the hypomorph growth of EfpA, a largely uncharacterized, but essential efflux pump in Mtb

Novel water-soluble, DNA-binding photosensitizer for the eradication of both Gram-negative and Gram-positive bacteria

Active-site-directed inactivator of bacterial beta-lactamases

Highly κ/μ-selective potent κ ligand

Reversible inhibitor of monoamine oxidase A, acting on epinephrine, norepinephrine, serotonin, and dopamine

Inhibitor of the reuptake of both dopamine and serotonin in the brain

Mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.

Antitumor agent

Novel PTP1B inhibitor

Novel Ca V channels blocker, binding in the central cavity of the pore on the intracellular side of the selectivity filter, physically blocking the ion-conducting pathway

Protein kinase C (PKC) activator

Novel proteasome inhibitor, protecting against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesis