Cat. No. | Product name | CAS No. |
DC21040 |
GB-83
GB-83 is a selective, reversible PAR2 (Protease-activated receptor 2) antagonist with IC50 of 2 uM. |
1252806-86-2 |
DC11740 |
GB-88
GB-88 is a selective, orally available PAR2 antagonist that inhibits PAR2 activated Ca(2+) release with IC50 of 2 uM. |
1416435-96-5 |
DC10153 |
GDC-0077
Featured
GDC-0077 is an orally available PI3K inhibitor with potential antineoplastic activity. GDC-0077 is extracted from patent WO 2017001645 A1, formula I. |
2060571-02-8 |
DC10035 |
GDC-0326
GDC-0326 is a potent and selective inhibitor of α-Isoform of Phosphoinositide 3-Kinase (PI3Kalpha inhibitor). |
1282514-88-8 |
DC8216 |
GDC-0349
GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM; >700-fold selectivity over PI3Kα and other 266 kinases. |
1207360-89-1 |
DC8519 |
GDC046
Featured
GDC046 is a potent lead analog with good kinase selectivity, physicochemical properties, and pharmacokinetic profile. |
1258292-64-6 |
DC8000 |
GDC-0623
Featured
GDC-0623 is a potent, ATP-uncompetitive inhibitors of MEK1(Ki=0.13 nM, +ATP). |
1168091-68-6 |
DC9942 |
GDC-0853(RG7845)
Featured
GDC-0853 is orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. |
1434048-34-6 |
DC23714 |
GDC-0927 R-form
GDC-0927 (SRN-927, RG-6047) is a potent, orally bioavailable, selective estrogen receptor degrader (SERD) for treatment of metastatic hormone receptor-positive/HER2-negative breast cancer.. |
1642297-53-7 |
DC23717 |
GDC-0927
GDC-0927 (SRN-927, RG-6047) is a potent, orally bioavailable, selective estrogen receptor degrader (SERD) for treatment of metastatic hormone receptor-positive/HER2-negative breast cancer.. |
1642297-01-5 |
DC12062 |
GDC-0927 Racemate
GDC-0927 Racemate is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases. |
1443983-36-5 |
DC9592 |
GDC-0941 (dimethanesulfonate)
GDC-0941 2 MeSO3H salt is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold). |
957054-33-0 |
DC7766 |
Ravoxertinib
Featured
GDC-0994 is a potent, orally available ERK1/2 inhibitor with IC50 of 1.1 nM and 0.3 nM, respectively. Phase 1. |
1453848-26-4 |
DC11504 |
GeA-69
Featured
GeA-69(GeA69) is a potent, selective, allosteric, cell-active PARP14 macrodomain 2 (MD2) inhibitor with Kd of 0.86 uM in ITC assays. |
2143475-98-1 |
DC7806 |
Geldanamycin (NSC122750)
Geldanamycin is a natural existing HSP90 inhibitor with Kd of 1.2 μM, specifically disrupts glucocorticoid receptor (GR)/HSP association. |
30562-34-6 |
DC12394 |
Gemcabene calcium
Gemcabene (PD-72953, PD72953) is a first-in-class lipid-lowering agent and activator of PARP. |
209789-08-2 |
DC12392 |
Gemcabene
Featured
Gemcabene (PD-72953, PD72953) is a first-in-class lipid-lowering agent and activator of PARP. |
183293-82-5 |
DC8487 |
Gemcitabine elaidate
Featured
Gemcitabine elaidate is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. |
210829-30-4 |
DC2107 |
Gemcitabine HCl (Gemzar,LY188011)
Featured
Gemcitabine Hydrochloride (Gemzar) is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively,showed potent activity against COVID-19(SARS-COV-2) with EC50 MERS-COV(1.216), SARS-COV(4.9 |
122111-03-9 |
DC2108 |
Gemcitabine free base
Gemcitabine(Gemzar) belongs to the group of medicines called antimetabolites. |
95058-81-4 |
DC3159 |
Gemifioxacin
Featured
Gemifloxacin mesylate (trade name Factive, Oscient Pharmaceuticals) is an oral broad-spectrum quinolone antibacterial agent used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. |
210353-53-0 |
DC12342 |
Gemilukast (ONO-6950)
Gemilukast is an orally active and potent dual cysteinyl leukotriene 1 and 2 receptors (CysLT1 and CysLT2) antagonist, with IC50s of 1.7, 25 nM for human CysLT1 and CysLT2, respectively. |
1232861-58-3 |