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TGFβRI-IN-3

  Cat. No.:  DC46417   Featured
Chemical Structure
2763602-67-9
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Field of application
TGFβRI-IN-3 inhibits TGFβR1 at an IC50 of 0.79 nM with 2000-fold selectivity against MAP4K4. TGFβRI-IN-3 represents a highly selective TGFβR1 inhibitor that has potential applications in immuno-oncology.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2763602-67-9
Chemical Name: TGFβRI-IN-3
Synonyms: TGFβRI-IN-3;TGFβRI IN 3,TGFβRIIN3;N-[2-(3-Methylphenyl)-4-pyridinyl]-7-[4-(methylsulfonyl)phenyl]-4-quinolinamine
SMILES: CC1C=C(C=CC=1)C1N=CC=C(NC2=CC=NC3C2=CC=C(C2C=CC(S(=O)(C)=O)=CC=2)C=3)C=1
Formula: C28H23N3O2S
M.Wt: 465.57
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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COA
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DC46417 TGFβRI-IN-3 TGFβRI-IN-3 inhibits TGFβR1 at an IC50 of 0.79 nM with 2000-fold selectivity against MAP4K4. TGFβRI-IN-3 represents a highly selective TGFβR1 inhibitor that has potential applications in immuno-oncology.
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