Cat. No. | Product name | CAS No. |
DC22183 |
NSC668394
NSC668394 (NSC 668394) is a small molecule inhibitor of ezrin, directly bind to ezrin with Kd of 12.59 uM. |
382605-72-3 |
DC10212 |
NSC-87877
NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation. |
56990-57-9 |
DC11260 |
NTCP binder peptide WD1
NTCP binder peptide WD1 is a macrocyclic peptide, pan-genotypic inhibitor of HBV cellular entry via targeting the cell-surface receptor for HBV, sodium taurocholate cotransporting polypeptide (NTCP, Kd=15 nM), reduces HBs antigen levels in culture supernatants. |
|
DC11259 |
NTCP binder peptide WL4
NTCP binder peptide WL4 is a macrocyclic peptide, pan-genotypic inhibitor of HBV cellular entry via targeting the cell-surface receptor for HBV, sodium taurocholate cotransporting polypeptide (NTCP, Kd=42 nM), reduces HBs antigen levels in culture supernatants with IC50 of 0.66 uM. |
|
DC21429 |
NTRC-844
NTRC-844 (NTRC844) is a potent, selective neurotensin receptor type 2 (NTS2) with Ki of 23 nM, 100-fold selectivity over NTS1 receptor. |
1811503-67-9 |
DC8716 |
NU6300
NU6300 is a non-covalent ATP-competitive CDK2 inhibitor (IC50 = 0.16 mM). |
|
DC24019 |
NU-6300
NU-6300 is the first covalent, irreversible, ATP-Competitive CDK2 inhibitor with Ki of 6 nM. |
2070015-09-5 |
DC26038 |
NUC-1031(SP)
NUC-1031(SP) is S form of NUC-1031 at P site.Acelarin (NUC-1031) is a ProTide transformation and enhancement of the widely-used nucleoside analogue, gemcitabine. |
1562406-27-2 |
DC26034 |
NUC3373(Fosifloxuridine nafalbenamide)
Featured
NUC-3373 is a phosphoramidate-based prodrug of the monophosphate form of 5-fluoro-2'-deoxyuridine, the active metabolite of fluorouracil,an antimetabolite fluoropyrimidine analog of the pyrimidine nucleoside, with potential antineoplastic activity. |
1332837-31-6 |
DC26035 |
NUC-7738
Featured
NUC-7738 is a phosphoramidate transformation of cordycepin (3’-deoxyadenosine; 3’-dA), a derivative of adenosine that was first isolated from Cordyceps sinensis. |
2348493-39-8 |
DC9416 |
Nuclear yellow
Nuclear yellow (Hoechst S769121) exhibits excitation/emission maxima ~335/495 nm when bound to DNA. |
74681-68-8 |
DC9486 |
Nucleozin
Featured
Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication. |
341001-38-5 |
DC3125 |
Nutlin-3
Featured
Nutlin 3 is a commercial available p53-MDM2 inhibitor, with Ki of 90 nM. |
548472-68-0 |
DC8454 |
Nutlin-3a
Featured
Nutlin-3a is arbitrarily referred to as enantiomer a because it appears as the first peak from chiral purification of racemic nutlin-3 and its absolute stereocenter assignment is not known. |
675576-98-4 |
DC8455 |
Nutlin-3b
Nutlin-3b is 150-fold less potent as an inhibitor of p53-MDM2 interaction than (−)-nutlin-3, demonstrating an IC50 value of 13.6 µM. |
675576-97-3 |
DC21931 |
NV01
NV01 is a small-molecule antagonist of the H3K9me3 binding to UHRF1 tandem tudor domain (TTD) with Kd of 5 uM.. |
902908-03-6 |
DC21932 |
NV03
NV03 is a small-molecule antagonist of the H3K9me3 binding to UHRF1 tandem tudor domain with Kd of 2.4 uM.. |
|
DC7988 |
NVP-DPP728 dihydrochloride
NVP DPP 728 is a potent and orally active inhibitor of dipeptidyl peptidase (DPP)-IV with Ki and IC50 values of 11 nM and 14 nM, respectively. |
207556-62-5 |
DC21430 |
NVP-2
Featured
NVP-2 is a potent and selective ATP-competitive cyclin dependent kinase 9 (CDK9) probe, inhibits CDK9/CycT activity with an IC50 of 0.514 nM. NVP-2 displays inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases with IC50 values of 0.584 µM, 0.7 |
1263373-43-8 |
DC8312 |
NVP-231
NVP-231 is a potent, specific, and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits binding of ceramide to CerK. |
362003-83-6 |
DC7250 |
NVP-BAG956(BAG 956)
NVP-BAG956(BAG 956) is a potent, ATP-competitive and selective dual PI3K and PDK1 inhibitor in vitro and in vivo,with IC50 values to be 56, 444, 34, 117 and 240 nM for PI3K p110 alpha, beta, delta and gamma and PDK1 kinases, respectively. |
853910-02-8 |
DC24053 |
NVP-BGJ398 phosphate
Featured
NVP-BGJ398 phosphate (Infigratinib phosphate, BGJ398 phosphate) is a potent, selective pan-FGFR inhibitor with IC50 of 0.9/1.0/1.4/60 nM for FGFR1/2/3/4, also shows high potenct against mutant FGFR3-K650E with IC50 of 4.9 nM. |
1310746-10-1 |