| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC21112 | AR-42 | A potent pan-HDAC inhibitor with IC50 of 16-30 nM, inhibits cell proliferation of P815, C2, and BR cells with IC50 of 0.65, 0.30, and 0.23 uM, respectively. |
|
| DC22925 | BMS-1001 hydrochloride Featured | A potent PD-1/PD-L1 interaction inhibitor with IC50 of 2.25 nM in a homogenous time-resolved fluorescence binding assay.. |
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| DC22928 | BMS-1001 Featured | A potent PD-1/PD-L1 interaction inhibitor with IC50 of 2.25 nM in a homogenous time-resolved fluorescence binding assay.. |
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| DC22936 | BMS-242 | A potent PD-1/PD-L1 interaction inhibitor with IC50 of 6-100 nM in a homogenous time-resolved fluorescence binding assay.. |
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| DC22935 | BMS-200 | A potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM in a homogenous time-resolved fluorescence binding assay.. |
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| DC22510 | AN-3199 | A potent PDE4 inhibitor with IC50 of 94.5 nM.. |
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| DC22850 | Genz 669178 | A potent PfDHODH inhibitor that exhibits low nanomolar in vitro potency against DHODH from P falciparum, P vivax, and P berghei. |
|
| DC22976 | PDE12-IN-3 | A potent phosphodiesterase 12 (PDE12) with Ki of 17.5 nM, with no activity for related enzyme CNOT6 (Ki>10 uM). |
|
| DC22588 | PK-14105 | A potent photoaffinity ligand for the peripheral-type benzodiazepine binding site with Ki of 4 nM. |
|
| DC25092 | Wortmannin Featured | A potent PI3K inhibitor with IC50 3 nM, does not inhibit PI4K activity. |
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| DC23322 | Vacuolin-1 Featured | A potent PIKfyve inhibitor that inhibits autophagy by impairing lysosomal maturation, potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A. |
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| DC25048 | CGP-53716 | A potent protein tyrosine kinase inhibitor that shows selectivity for PDGFR in vitro and in cells. |
|
| DC22624 | Asenapine | A potent psychopharmacologic agent that shows high affinity for 5-HT, dopamine, histamine and adrenoceptors. |
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| DC11772 | AZD-4316 | A potent respiratory syncytial virus (RSV) fusion inhibitor.. |
|
| DC22929 | KIN-1400 | A potent RIG-I-like receptor (RLR) agonist that triggers IRF3-dependent innate immune antiviral genes and IFN-β expression. |
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| DC11647 | JNJ-2408068 Featured | JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg[1]. |
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| DC22791 | Kinase inhibitor C1 | A potent small molecule inhibitor of MELK kinase activity with IC50 of 42 nM. |
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| DC11830 | WK-298 | A potent small molecule inhibitor that binds and disrupts the MDM2/MDMX-p53 interaction with IC50 of 0.19 uM and 19.7 uM, respectively.. |
|
| DC21417 | NSC 141562 | A potent small-molecule inhibitor of the MIR155 host gene/miR-155 axis. |
|
| DC5132 | Tropisetron HCL | A potent SR-3 antagonist |
|
| DC22530 | WEHI-345 analog | A potent Src inhibitor extracted from patent WO/2012003544A1.. |
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| DC20416 | Imipramine Blue | A potent STAT5 inhibitor with a dual mechanism of action, potently inhibits STAT5 through liberation of endogenous phosphatase activity following NADPH oxidase (NOX) inhibition at 200-300 nM. |
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| DC22933 | TLR7-Agonist-31 | A potent TLR7 agonist with EC50 of 59 nM.. |
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| DC22932 | TLR7-Agonist-54 | A potent TLR7 agonist with EC50 of 8.6 nM. . |
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| DC22393 | IW-927 | A potent TNFα/TNFRc1 interaction antagonist with IC50 of 50 nM, with no affinity for the related cytokine receptors TNFRc2 or CD40, and no cytotoxicity (>100 uM). |
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| DC22618 | MMAD hydrochloride | A potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs).. |
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| DC22607 | Masitinib mesylate | A potent tyrosine kinase inhibitor targeting c-Kit and PDGFR with IC50 of 0.15 and 0.05 uM in cell based assays. |
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| DC23995 | Lck inhibitor 2 Featured | A potent tyrosine kinases inhibitor with IC50 of 13/9/3/26/2 nM for Lck/Btk/Lyn/Syk/Txk.. |
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| DC11922 | BC-1382 | A potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction with IC50 of 5 nM. |
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| DC22374 | BMS-299897 | A potent γ-secretase inhibitor that preferentially inhibits cleavage of the APP CTF cleavage with IC50 of 7.1 nM. |
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