Cat. No. | Product name | CAS No. |
DC22924 |
3M-002
A selective TLR8 agonist that induces activation of NF-κB at 0.4 uM. |
256922-53-9 |
DC20306 |
AMTB hydrochloride
Featured
A selective TRPM8 channel blocker with pEC50 of 6.91 in Ca(2+) influx assay, with no activity for TRPV4 (pEC50<4.6). |
926023-82-7 |
DC23226 |
Guanfacine
A selective α2A receptor agonist that can reduce peripheral sympathetic outflow and thus cansues a reduction in peripheral sympathetic tone. |
29110-47-2 |
DC24156 |
Metoprolol
A selective β1 receptor blocker used in treatment of several diseases of the cardiovascular system, especially hypertension.. |
51384-51-1 |
DC26107 |
TRV0109101 hydrochloride
A selective, G protein-biased µ-opioid receptor agonist, does not promote the development of opioid-induced mechanical allodynia (OIMA) and rapidly reverses allodynia in vivo.. |
2101210-22-2 |
DC26103 |
TRV0109101
A selective, G protein-biased µ-opioid receptor agonist, does not promote the development of opioid-induced mechanical allodynia (OIMA) and rapidly reverses allodynia in vivo.. |
1401027-29-9 |
DC11737 |
GNF-6702
A selective, non-competitive inhibitor of the kinetoplastid proteasome, inhibits the chymotrypsin-like activity of the T. cruzi proteasome with IC50 of 35 nM. |
1799329-72-8 |
DC21728 |
TAK-070
A selective, nonpeptidic, noncompetitive BACE1 inhibitor with IC50 of 3.15 uM in cell-free assays. |
365276-12-6 |
DC20995 |
EP009
A selective, orally active JAK3 inhibitor that reduces IL-2-mediated JAK3 tyrosine phosphorylation with cellular IC50 of 10-20 uM. |
1462951-30-9 |
DC20287 |
δ-secretase inhibitor 11
A selective, orally bioactive and brain permeable δ-secretase (AEP. |
842964-18-5 |
DC12005 |
Iberiotoxin
A selective, potent peptidyl blocker of the big conductance Ca2+-activated K+ channel (BKCa, KCa1.1, MaxiK) with IC50 of 0.25 nM. |
129203-60-7 |
DC12006 |
Charybdotoxin
A selective, potent peptidyl blocker of the big conductance Ca2+-activated K+ channel (BKCa, KCa1.1, MaxiK). |
95751-30-7 |
DC11884 |
Sercloremine hydrochloride
A selective, reversible inhibitor of MAO-A and serotonin reuptake inhibitor as an antidepressant.. |
54403-20-2 |
DC11885 |
Sercloremine
A selective, reversible inhibitor of MAO-A and serotonin reuptake inhibitor as an antidepressant.. |
54403-19-9 |
DC22971 |
CDE 096
A selective, reversible, high-affinity PAI-1 inhibitor that prevents PAI-1 from inactivating tPA and uPA with similar potency (IC50=30 and 25 nM, respectively). |
1228357-04-7 |
DC21780 |
UNC-3230
A selective, small molecule inhibitor of PIP5K1C with IC50 of 41 nM, does not ihibits other lipid kinases including PI3Ks. |
1031602-63-7 |
DC21400 |
NS-1209
A selective, water-soluble, in vivo long-lasting AMPA antagonist with Ki of 43 nM. |
245063-59-6 |
DC22451 |
AQX 1125 acetate
A sepecific, orally bioavailable SHIP1 activator with no effect on functional androgen, oestrogen, oestrogen-related receptor α, glucocorticoid, mineralocorticoid and progesterone receptor at 30 uM. |
782487-29-0 |
DC23981 |
BCX-1470 methanesulfonate
Featured
A serine protease inhibitor that inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM). |
217099-44-0 |
DC22666 |
Levosalbutamol
A short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).. |
34391-04-3 |
DC23231 |
Levalbuterol tartrate
A short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).. |
661464-94-4 |
DC22828 |
DBCO-Amine
A simple DBCO-containing building block used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond. |
1255942-06-3 |