| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC9580 | Anagrelide (hydrochloride) | Anagrelide Hydrochloride(BL4162A) is a drug used for the treatment of essential thrombocytosis. |
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| DC11649 | Jamaicin (AnCoA4) Featured | AnCoA4 (AnCoA-4, AnCoA 4) is a potent Orai1 channel inhibitor that inhibits store-operated calcium (SOC) with EC50 of 0.88 uM. |
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| DC20085 | Androgen receptor modulators 1 | Androgen receptor modulators 1 is a selective androgen receptor modulator (SARM). Androgen receptor modulators 1 has strong agonistic activities with an EC50 of 4.7 nM. |
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| DC12143 | Anemarrhenasaponin I | Anemarrhenasaponin I, a traditional Chinese medicine, is isolated from Anemarrhena asphodeloides Bunge. |
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| DC12113 | Anemarsaponin E | Anemarsaponin E is extracted from Anemarrhena asphodeloides Bunge and has anti-inflammatory activity. |
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| DC24123 | Angiotensin 1-7 | Angiotensin (1-7) (Ang-(1-7)) is an active heptapeptide of the Renin-angiotensin system (RAS), inhibits purified canine angiotensin converting enzyme (ACE) activity with IC50 of 0.65 uM. |
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| DC9348 | Angiotensin II human | Angiotensin II human is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure. |
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| DC24109 | Anguizole | Anguizole is a HCV NS4B inhibitor targeting second amphipathic helix of NS4B (NS4B-AH2), blocks genotype 1b HCV replication with EC50 of 310 nM. |
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| DC8241 | Ansamitocin P-3 Featured | Ansamitocin P-3, a potent anti-tumor maytansinoid found in Actinosynnema pretiosum, is a maytansine analog which displays potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29. |
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| DC20671 | ANT431 sodium | ANT431 sodium is a novel, highly water-soluble metallo-β-lactamase (MBL) inhibitor with IC50 of 290 nM and 195 nM for NDM-1 and VIM-2, shows a comparatively weak inhibitor of VIM-1 and IMP-1 (Ki of 14.6 and 4.15 uM, respectively). |
|
| DC11088 | Fosmanogepix | antifungal. |
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| DC23276 | Antimalarial compound 49c | Antimalarial compound 49c is a potent antimalarial peptidomimetic inhibitor originally developed against Plasmepsin II selectively targets TgASP3, PfPMIX, and PfPMX, shows very potent antimalarial effects only after 72 h of treatment with IC50 of 0.6 nM. |
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| DC20308 | Antimycin A | Antimycin A is an inhibitor of cellular respiration, specifically oxidative phosphorylation, binds to the Qi site of cytochrome c reductase, disrupts the Q-cycle of enzyme turn over. |
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| DC22094 | ANY1 | ANY1 (FosA inhibitor ANY1) is a small molecule active site inhibitor of FosA (metal-dependent glutathione S-transferase) with IC50 of 5.1 uM (K. pneumoniae FosA). |
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| DC10950 | AOH1160 | AOH1160 is a potent, first-in-class, orally available small molecule inhibitor of Proliferating cell nuclear antigen (PCNA). |
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| DC11196 | AP14145 | AP14145 (AP-14145) is a potent, selective negative allosteric modulator of KCa2.2 and KCa2.3 with equal potency (IC50=1.1±0.3 uM). |
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| DC20078 | AP1867 Featured | AP1867 is a synthetic FKBP12F36V-directed ligand. |
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| DC22207 | AP1903 Featured | AP1903 (Rimiducid, AP-1903) is a potent, specific synthetic ligand of FKBP Phe36Val mutant (F36V-FKBP) with binding IC50 of 1.8 nM. |
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| DC8581 | AP219 | AP219 is a control compound for AP39, containing the triphenylphosphonium scaffold but lacking the H2S-releasing portion. |
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| DC1020 | Ponatinib (AP24534) Featured | AP24534 is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM, respectively. |
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| DC5198 | ALK-IN-1 (Brigatinib analog) Featured | ALK-IN-1 (Brigatinib analog) is a potent and selective active inhibitor of anaplastic lymphoma kinase(ALK), Patent US20140066406 A1. |
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| DC12705 | APA modulator T4 | APA modulator T4 is a small modulator of alternative polyadenylation (APA) with IC50 of 2.1 uM in reporter assays, modulates endogenous APA via nonkinase-mediated pathways and promotes distal-to-proximal (DtoP) APA usage in multiple transcripts. |
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| DC12706 | APA modulator T5 | APA modulator T5 is a small modulator of alternative polyadenylation (APA), modulates endogenous APA via nonkinase-mediated pathways and promotes distal-to-proximal (DtoP) APA usage in multiple transcripts. |
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| DC12636 | Apararenone Featured | Apararenone (MT-3995) is a novel potent, selective non-steroidal mineralocorticoid receptor antagonist for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis.. |
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| DC20310 | Apcin Featured | Apcin is a cell-permeable, small molecule anaphase-promoting complex/cyclosome (APC/C) inhibitor, which binds to Cdc20 and competitively inhibits the ubiquitylation of D-box-containing substrates. |
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| DC11428 | Olorinab | APD-371 (APD371, Olorinab) is a potent, selective and orally available CB2 agonist with EC50 of 6.2 nM; displays no activity against CB1 receptors (EC50>10 uM); exhibits activity in rat model of osteoarthritis pain. |
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| DC22430 | APD916 | APD916 is a potent and selective antagonist of the H3 receptor with Ki of 0.7 nM for rH3R. |
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| DC11077 | Azelaprag | apelin receptor. |
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| DC21448 | Apicidin Featured | Apicidin (OSI 2040) is a fungal metabolite that exhibits potent, broad spectrum antiprotozoal activity in vitro, potently inhibits HDAC with IC50 of 0.7 nM in an enzyme activity assay. |
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| DC23406 | Aplaviroc | Aplaviroc (GSK-873140. |
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