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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DCC2661 Idr-0081053 Novel bactericidal agent against M. tuberculosis under acidic conditions, being effective at sterilizing cultures in a concentration-dependent fashion at the highest concentrations
DCC2662 Idr-0099118 Novel concentration dependent bactericidal agent against M. tuberculosis, being markedly more efficient at killing M. tuberculosis under acidic conditions
DCC2663 Idr-1002 Innate Defence Regulator Peptide, Enhancing Monocyte Migration and Adhesion on Fibronectin
DCC2664 Idr-1018 Tfa Salt Novel immunomodulatory and antibiofilm innate defense regulator peptide
DCC2665 Idrapril Angiotensin converting enzyme (ACE) inhibitor
DCC2666 Iferanserin Selective serotonin 5-HT2A receptor antagonist
DCC2667 Ifn-1 Inducer C3 Novel Type I Interferon Inducer
DCC2668 Ifn-1 Inducer E51 Novel Type I Interferon Inducer
DCC2669 Ifn-1 Inducer L56 Novel Type I Interferon Inducer; Intercalator of DNA; Inhibitor of the retrovirus replications including HIV
DCC2670 Igf2bp2/imp2 Inhibitor 4 First Small-Molecule Inhibitor of RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy
DCC2671 Igf2bp2/imp2 Inhibitor 6 Novel Inhibitor of RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy
DCC2672 Igf2bp2/imp2 Inhibitor 9 Novel Inhibitor of RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy
DCC2673 Iglu-antagonist-21a Highly potent fluorescent iGlu receptor antagonist
DCC2674 Ihr-saha Novel dual SMO-HDAC antagonist, retaining similar specificity for SAHA-targeted HDACs, disabling deviant Hedgehog signaling and preventing GLI binding to DNA
DCC2675 Ikarugamycin Natural Inhibitor of Clathrin-Mediated Endocytosis
DCC2676 Ikkß-in-124 Novel allosteric inhibitor of IκBα phosphorylation and NF-κB transcriptional activity through selective capture of the inactive conformation and hence blockade of IKKβ S177/S181 phosphorylation
DCC2677 Ilmofosine Antineoplastic phospholipid, being effective against many tumor types, including ovary, non-small cell lung, kidney, and melanoma, exhibiting competitive inhibition of protein kinase C (PKC) activity
DCC2678 Iloperidone Hydrochloride Dual D 2 /5-HT 2 antagonist as an antipsychotic agent
DCC2679 Imarikiren Dihydrochloride Novel orally effective direct renin inhibitor for treating diabetic nephropathy and hypertension
DCC2680 Imb-xma0038 Novel anti-tuberculosis agent, targeting Mycobacterial tuberculosis (Mtb) aspartate semialdehyde dehydrogenase
DCC2681 Imb-yh-8 Novel inhibitor of protein kinase B (PknB), inhibiting PknB auto-phosphorylation and the phosphorylation of GarA by PknB in a dose-dependent manner
DCC2682 Imc-48 BCL2 i-motif-interactive compound, stabilizing or facilitating the folding of the i-motif
DCC2683 Imc-76 BCL2 i-motif-interactive compound, destabilizing or unfolding the i-motif
DCC2684 Imidacloprid Insect neurotoxin, blocking nicotinic acetylcholine receptors and preventing acetylcholine from transmitting impulses between nerves
DCC2685 Imm-h004 Novel potent inhibitor of BV2 microglia activation, protecting PC12 cells and primary neurons against indirect toxicity mediated by exposure to conditioned medium (CM) from LPS-treated BV2 cells
DCC2686 Imp-1002 Novel resistance breaking antimalarial N-myristoyltransferase (NMT) inhibitor, binding to NMT peptide binding pocket
DCC2687 Imp-1700 Novel cell-active and potent inhibitor of bacterial DNA repair, potentiating quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus
DCC2688 Imp2070 Novel Probe for NLRP3 Inflammasome Inhibitor MCC950
DCC2689 Impdh-in-1 First in-class allosteric inhibitor of a bacterial IMPDH, showing to counteract the activation by the natural positive effector, MgATP, and to block the enzyme in its apo conformation
DCC2690 Imprimatin-c1 Novel plant immune-priming agent, acting as a partial agonist of salicylic acid

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