Novel inhibitors

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Cat. No.	Product Name	Field of Application
DCC2601	Hsp27-in-i	Novel inhibitor of heat shock 27 kDa protein (HSP27), significantly inducing AR degradation in GBM cells via the proteasomal pathway, selectively inhibiting AR-overexpressed GBM cell growth with IC 50 values around 5 nM
DCC2602	Hsp90-aha1 Inhibitor A16	Novel Hsp90-Aha1 chaperone complex formation inhibitor, enhancing F508del-CFTR channel activity
DCC2603	Hsp90-in-30f	Novel potent inhibitor of heat shock protein 90 (Hsp90), effectively reducing the expression levels of Hsp90 client proteins including Her2, EGFR, Met, Akt, and c-Raf
DCC2604	Hsp90-in-89	Novel heat shock protein 90 (Hsp90) inhibitor
DCC2605	Hsp90-in-s89	Novel heat shock protein 90 (Hsp90), more potent enantiomer
DCC2606	Htl0028016	Novel macrocyclic calcitonin gene-related peptide (CGRP) receptor antagonist
DCC2607	Htl0028125	Novel macrocyclic calcitonin gene-related peptide (CGRP) receptor antagonist
DCC2608	Htl26119	Novel allosteric antagonist of the glucagon-like peptide-1 receptor (GLP-1R)
DCC2609	Htl6641	Novel, potent, selective, and orally efficacious dual antagonist of the orexin receptors
DCC2610	hts05737	Novel activator of PC2
DCC2611	Huhs029	Novel analgesic agent, activating TRPA1 and subsequently desensitizing the channel, exhibiting higher inhibitory activity than resveratrol
DCC2612	Human Vitronectin (351-359)	Adhesive peptide (sequence 351-359 mapped on the Human Vitronectin Protein), covalent and selective functionalizing on glass and titanium surfaces, increasng osteoblast attachment and adhesion strength and to promoting osseointegration
DCC2613	Hur-ligand-4	Novel human antigen R (HuR) ligand, acting as a HuR-RNA interferer
DCC2614	Hy1-pt	Novel CK2-Specific Pt(II) Compound, Reversing Cisplatin-Induced Resistance by Inhibiting Cancer Cell Stemness and Suppressing DNA Damage Repair in Non-small Cell Lung Cancer Treatments
DCC2615	Hycanthone Mesylate	Inhibitor of apurinic endonuclease-1 (APE1) by direct protein binding
DCC2616	Hydro-1080	Activable Probe for Noninvasive Hydroxyl Radical Imaging, emitted in 1000-1400 nm after responding to ·OH
DCC2617	Hydrocaffeoyl-fasudil 1d	Novel multitarget Fasudil derivative, inducing the NRF2 signature, promoting the expression of the antioxidant response enzymes HO-1 and NQO1, via a KEAP1-dependent mechanism
DCC2618	Hydrolapachol	Novel potent and selective inhibitor of Schistosoma mansoni dihydroorotate dehydrogenase (SmDHODH)
DCC2619	Hydroxyellipticine-1a	Novel selective r(CGG)exp probe, improving pre-mRNA splicing defects, inhibiting formation of nuclear inclusions and RANT in a FXTAS cellular model
DCC2620	Hydroxymatairesinol	Natural antioxidant and anti-cancer agent, blocking the MAPK/NF-κB and activating Nrf2/HO-1
DCC2621	Hydroxytriolein	Novel anticancer agent, inhibiting lung cancer cell proliferation via a PKCa and ERK1/2 dependent mechanism
DCC2622	Hymenidin	Natural antagonist of serotonergic receptors and inhibitor of CDK5/p25 and GSK-3ß
DCC2623	Hys-32	Novel analogue of combretastatin A-4, enhancing connexin43 expression
DCC2624	Hz-ma Hybrid 11b	Novel potent and selective inhibitor of fat mass obesity-associated protein (FTO), being selectively over alkylation repair homologue 5 (ALKBH5), another DNA/RNA demethylase
DCC2625	Iag-10	Novel potent and selective inhibitor of human DNA polymerase kappa (hpol κ)
DCC2626	Ianthellamide A	Selective kynurenine-3-hydroxylase inhibitor
DCC2627	Ianthelliformisamine A Tfa Salt	Antibiotic enhancer against resistant Gram-negative bacteria
DCC2628	Ianthelliformisamine B Tfa Salt	Antibiotic enhancer against resistant Gram-negative bacteria
DCC2629	Ianthelliformisamine C Tfa Salt	Antibiotic enhancer against resistant Gram-negative bacteria
DCC2630	Iap-in-1	Novel antagonist of IAP (inhibitor of apoptosis protein)

Novel inhibitors

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