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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DCC3250 Mbx2546 Novel specific inhibitor of HA-mediated viral entry, inhibiting HPAI H5N1 virus strain A/Hong Kong/H5N1
DCC3251 Mc1220 Topical nonnucleoside reverse transcriptase inhibitor, partially preventing vaginal RT-SHIV infection of macaques
DCC3252 Mc-1353 Potent and HDAC class I-selective inhibitor
DCC3253 Mc1420 Novel potent acetylcholinesterase (AChE) inhibitor
DCC3254 Mc-1-f2 The first inhibitor of forkhead Box Protein C2 (FOXC2)
DCC3255 Mc2050 Novel selective PARP1 inhibitor, inhibitng apoptosis and blocking poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells
DCC3256 Mc2392 Novel hybrid retinoid-HDAC inhibitor
DCC3257 Mc-70 Hydrochloride Potent P-gp inhibitor with good selectivity towards BCRP pump (EC50 values 0.05 μM, 0.69 μM, 9.3 μM, and 73 μM for Caco-2, MDR1, MRP1, and BCRP inhibition, respectively)
DCC3258 Mca-13 Novel neurotropic agent
DCC3259 Mca-yvadapk(dnp)-oh Specific and highly fluorescent substrate for caspase-1, also acting as a substrate for caspase-4
DCC3260 Mcc1019 Novel selective inhibitor of the Polo-box domain of Polo-like kinase 1 (PLK1)
DCC3261 Mcc1189 First-in-class inhibitor of MFS efflux pump CaMdr1p
DCC3262 Mcc-134 Novel inverse agonist for the pancreatic-type ATP-sensitive K channel as vascular relaxing agent
DCC3263 MCC950 free acid Featured Potent and selective inhibitor of NLRP3, reducing interleukin-1β (IL-1β) production in vivo and attenuating the severity of experimental autoimmune encephalomyelitis (EAE)
DCC3264 Mc-doxhzn Albumin-binding prodrug of Doxorubicin
DCC3265 Mcg315 Novel potent F508del-CFTR corrector, modulating poly-ADP ribose polymerase 3 and poly-ADP ribose polymerase 16 activities
DCC3266 Mci-225 Selective NA reuptake inhibitor with 5-HT3 receptor antagonism
DCC3267 Mcl0527-3 Novel inhibitor of p53-MDM2 interaction
DCC3268 Mcl-1 Degrader C3 Novel potent and selective degrader of Mcl-1
DCC3269 Mcl-1 Inhibitor-11 Novel reversible covalent inhibitor for Mcl-1 with improved water solubility than Mcl-1 Inhibitor-5
DCC3270 Mcl-1 Inhibitor-39 Novel selective Mcl-1 inhibitor
DCC3271 Mcl-1 Inhibitor-5 The first reversible covalent inhibitor for Mcl-1, a protein-protein interaction (PPI) target
DCC3272 Mcl1-in-1 Novel potent and selective inhibitor of the apoptosis regulating proteins Mcl-1
DCC3273 Mcmmad Featured Novel mc (maleimidocaproyl) linker plus MMAD (Monomethylauristatin D) to be used for prepare antibodies conjugates via cysteine-capped mechanism
DCC3274 Mct4-in-18n Novel highly selective inhibitor of monocarboxylate transporter 4 (MCT4/SLC16A3), resulting in lactate efflux inhibition and reduction of cellular viability in MCT4 high expressing cells
DCC3275 Mcule-5948770040 Novel SARS-CoV-2 Main Protease (Mpro) inhibitor, binding to Subsites S1 and S2 (Kd=1.3 µM)
DCC3276 Md-222 First-in-class highly potent PROTAC degrader of MDM2
DCC3277 Md-39-am Diuretic agent, impling an increase in the Na+ excretion and showing antihypertensive effect
DCC3278 Mdc-1112 Novel valproic acid (VPA) derivative, as a potent STAT3 inhibitor
DCC3279 Mdcccl1636 Novel partial PPARgamma ligand, displaying partial agonist activity in biochemical and cell-based transactivation assays, and reversed insulin resistance

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