| DC8383 |
Dp44mT
Featured
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Dp44mT is a potent iron chelator, which shows selective antitumor activity. |
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| DC23775 |
DPA-714 |
DPA-714 is a potent, selective ligand for the translocator protein (TSPO) with Ki of 7.0 nM. |
|
| DC20966 |
DPM-1001
Featured
|
DPM-1001 is a potent, selective, orally bioavailable inhibitor of the protein-tyrosine phosphatase PTP1B with IC50 of 100 nM, also chelates copper, which enhanced its potency as a PTP1B inhibitor. |
|
| DC20366 |
DRAK2-IN-16 |
DRAK2-IN-116 is a potent, selective DRAK2 inhibitor with IC50 of 3 nM, shows weak inhibition for DRAK1 (IC50=51 nM) and no significant activity against DAPK1/2/3 (IC50>1 uM).. |
|
| DC20103 |
D-Ribose(mixture of isomers)
Featured
|
D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation |
|
| DC20967 |
DRI-C21045 |
DRI-C21045 is a novel small-molecule inhibitor of CD40-CD40L protein-protein interaction with IC50 of 0.17 uM in cell-based assays. |
|
| DCAPI1562 |
Drospirenone
Featured
|
Drospirenone is a synthetic progestogen exhibiting antiandrogenic and antimineralocorticoid activity. |
|
| DC2056 |
Droxidopa (L-DOPS,SM-5688)
Featured
|
Droxidopa (L-DOPS) is a psychoactive drug and acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). |
|
| DC12598 |
DRV1 (GPR32) agonist C2A |
DRV1 (GPR32) agonist C2A (NCGC00135472) is a synthetic molecule that activate human resolvin D1 receptor DRV1/GPR32 receptor with EC50 of 0.37 uM and 0.05 uM in β-arrestin and cAMP assays, respectively. |
|
| DC20968 |
DS-1040 |
DS-1040 (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa. |
|
| DC20969 |
DS-1040 tosylate |
DS-1040 tosylate (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa. |
|
| DC20970 |
DS-1040 tosylate hydrate |
DS-1040 tosylate hydrate (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa. |
|
| DC20974 |
DS16570511 |
DS16570511 is a cell-permeable inhibitor of the mitochondrial calcium uniporter (MCU) that inhibits serum-induced mitochondrial Ca2+ influx in HEK293A cells with IC50 of 7 uM. |
|
| DC20975 |
DS-2330
Featured
|
DS-2330 is a phosphorous lowering agent for treating hyperphosphatemia in chronic kidney disease.. |
|
| DC20971 |
DS-2969b |
DS-2969b (DS 11960558) is a novel orally active GyrB inhibitor, inhibits the supercoiling activity of C. difficile DNA gyrase with IC50 of 20 ng/mL. |
|
| DC12410 |
8-{1-[(1R,4R)-4-aminocyclohexyl]ethenyl}-5,5-dimethyl-5,6-dihydrobenzo[h]quinazolin-4-amine
Featured
|
DS42450411 (DS 42450411, DS-42450411) is a potent, orally active hepcidin production inhibitor with IC50 of 32 nM. |
|
| DC22082 |
DS-437
Featured
|
DS-437 is a potent, selective, dual inhibitor of PRMT5 and PRMT7 with IC50 of 6.0 uM for both, DS-437 is inactive against 29 other human protein-, DNA-, and RNA-methyltransferases. |
|
| DC12411 |
DS-6930
Featured
|
DS-6930 (DS 6930, DS6930) is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%; significantly recruits several cofactors, such as RIP140 and PGC1, in cofactor recruitment assays; demonstrateshigh PPARγ agonist potency with robust plasma glucose reduction, maintains diminished PPARγ-related adverse effects upon toxicological evaluation in vivo, and demonstrated no hepatotoxicity. |
|
| DC22083 |
DS-6930b |
DS-6930b (DS-6930 calcium salt) is the calcium salt of DS-6930, which is a novel potent, selective PPARγ agonist with EC50 of 41 nM, Emax-68%. |
|
| DC20976 |
DS-7423
Featured
|
DS-7423 is a novel potent, small-molecule dual inhibitor of PI3K/mTOR with IC50 of 15.6, 1143, 249, 262 and 34.9 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, and mTOR respectively. |
|
| DC20973 |
DS86760016 |
DS86760016 is a novel selective bacterial leucyl-tRNA synthetase (LeuRS) inhibitor with IC50 of 0.38 uM (Escherichia coli, LeuRS). |
|
| DC22081 |
DS88790512 hydrochloride |
DS88790512 is a potent, selective, and orally bioavailable blocker with IC50 of 11 nM, exhibits excellent selectivity against hERG and hNaV1.5 channels (IC50 >100 uM).. |
|
| DC22080 |
DS88790512 |
DS88790512 is a potent, selective, and orally bioavailable blocker with IC50 of 11 nM, exhibits excellent selectivity against hERG and hNaV1.5 channels (IC50 >100 uM).. |
|
| DC12193 |
Ds-HAPP |
Ds-HAPP is an anthrancenyl and dansyl fluorophore ligand. |
|
| DC12643 |
DSP-0565 |
DSP-0565 (DSP0565) is a new drug candidate with broad anti-convulsant activity, does not bind to any GABA-A binding sites, may be caused as the result of its GABAergic function via novel target.. |
|
| DC20977 |
DSP-1053 |
DSP-1053 is a novel potent serotonin reuptake (SERT) inhibitor with 5-HT1A partial agonistic activity that binds to human serotonin transporter and 5-HT1A receptor with Ki of 1.02 and 5.05 nM, respectively. |
|
| DC26008 |
DSP2230
Featured
|
DSP-2230 is a selective Nav1.7/Nav1.8 blocker. |
|
| DC20979 |
DSP-6952 hydrobromide |
DSP-6952 is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c. |
|
| DC20980 |
DT204 |
DT204 (DT-204) is a novel SCFSkp2 inhibitor that reduces Skp2 binding to Cullin-1 and Commd1, synergistically enhances BTZ-induced apoptosis. |
|
| DC20367 |
dTRIM24
Featured
|
dTRIM24 is a potent TRIM24 bromodomain inhibitor with IC50 of 217.8 nM (TRIM24 ligand displacement). |
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