| DC20989 |
EBI-1051 |
EBI-1051 is a novel and orally efficacious MEK inhibitor with IC50 of 10.8 nM against MEK1, inhibits viability of colo-205 cells with IC50 of 4.7 nM. |
|
| DC23818 |
EBI-907 |
EBI-907 is a highly potent, selective, orally active B-Raf V600E inhibitor with enzyme IC50 of 7 nM, A375 cell growth IC50 of 13 nM. |
|
| DC9848 |
Ebselen
Featured
|
Ebselen is a selenium-based inhibitor of protein kinase C, NADPH, 5-lipoxygenase, cyclooxygenase (COX) and NADPH oxidase. |
|
| DC20123 |
EC0489 |
EC0489, a conjugate of folic acid and desacetyl vinblastine hydrazide, is a high-affinity ligand for the folate receptor (FR). Refractory or metastatic Tumor. Small molecule-drug conjugate (SMDC). |
|
| DC10277 |
EC330
Featured
|
EC330 is a leukemia inhibitory factor (LIF) inhibitor. |
|
| DC10980 |
EC-359 |
EC-359 (EC359) is a first-in-class, orally available inhibitor of leukemia inhibitory factor (LIF), blocks LIF-LIFR interaction and binds to LIFR with affinity of 81 nM in SPR assay. |
|
| DC20990 |
EC-70124 |
EC-70124 is a multikinase inhibitor with potent activity against several AML related kinases including FLT3, JAK, SYK or Pim kinases (Kd<10 nM). |
|
| DC26057 |
Ecabet (sodium salt)
Featured
|
Ecabet is an antiulcerative and gastroprotective agent. |
|
| DCAPI1162 |
Ecdysone |
Ecdysone |
|
| DCAPI1408 |
Echinocandin B0 |
Echinocandin B0 |
|
| DC9912 |
Echinocystic acid
Featured
|
Echinocystic acid a pentacyclic triterpene isolated from the fruits of Gleditsia sinensis Lam, has potent antioxidant, anti-inflammatory and anti-tumor properties. |
|
| DCAPI1126 |
Econazole nitrate (Spectazole) |
Econazole nitrate (Spectazole) |
|
| DC21514 |
Ecopladib |
Ecopladib (PLA 725) is a potent, selective and orally active inhibitor of cPLA2α with IC50 of 0.15 and 0.11 uM in GLU micelle and rat whole blood assays, respectively. |
|
| DCAPI1380 |
Edaravone (MCI-186) |
Edaravone (MCI-186) |
|
| DC21002 |
Edelfosine
Featured
|
Edelfosine is a synthetic lysophospholipid analog that selectively inhibits PLC with IC50 of 9.6 uM in fibroblasts and adenocarcinoma cells. |
|
| DC23562 |
Edivoxetine |
Edivoxetine (LY2216684) is a novel potent, selective norepinephrine reuptake inhibitor (NERI) being evaluated as adjunctive treatment for major depressive disorder (MDD).. |
|
| DC23628 |
Edivoxetine hydrochloride |
Edivoxetine (LY2216684) is a novel potent, selective norepinephrine reuptake inhibitor (NERI) being evaluated as adjunctive treatment for major depressive disorder (MDD).. |
|
| DC10762 |
Edonerpic maleate
Featured
|
Edonerpic, also known as T-817, is a neuroprotectant. Edonerpic is a candidate therapeutic agent for Alzheimer's disease that inhibits oxidative stress and nitric oxide-induced neurotoxicity and acts as a neurotrophic factor. Edonerpic protects against MPTP-induced neurotoxicity by blocking lipid peroxidation in the SNc, and imply that this compound may be useful for treating neurodegenerative disorders related to oxidative stress, such as Parkinson's disease. |
|
| DC7819 |
Efaproxiral sodium
Featured
|
Efaproxiral Sodium is a synthetic allosteric modifier of hemoglobin, used for brain metastases originating from breast cancer. |
|
| DC9772 |
Efinaconazole(KP-103)
Featured
|
Efinaconazole(KP-103) is a novel triazole antifungal drug currently under development as a topical treatment for onychomycosis. |
|
| DC21515 |
Efipladib |
Efipladib (PLA 902) is a potent, selective and orally active inhibitor of cPLA2α with IC50 of 20 nM for LTB4 inhibition. |
|
| DC10261 |
Eflornithine hydrochloride hydrate |
Eflornithine(Difluoromethylornithine) inhibits polyamine biosynthesis by the selective, irreversible inhibition of ornithine decarboxylase (ODC). A chemoprotective agent that blocks angiogenesis. Its biological half-life is 8 hours. |
|
| DC11379 |
Efpeglenatide |
Efpeglenatide is a new once-2eekly GLP-1 Injection for Type 2 Diabetes |
|
| DC20992 |
eFT226 |
eFT226 is a novel, potent and selective eIF4A inhibitor with anti-tumor activity in B-cell malignancies, promotes eIF4A binding to specific mRNA sequences and interferes with the assembly of the eIF4F initiation complex. |
|
| DC22086 |
EG00229 free base |
EG00229 is a specific inhibitor of neuropilin-1 (NRP1)/VEGF-A interaction, inhibits the binding of biotinylated VEGFA to NRP1 with IC50 of 8 uM. |
|
| DC22087 |
EG01377 |
EG01377 is a potent and bioavailable inhibitor of the NRP1/VEGF-A interaction (Kd=1.32 uM), selective for NRP1 over the closely related protein NRP2. |
|
| DC12303 |
Eg5 Inhibitor V, trans-24 |
Eg5 Inhibitor V, trans-24 is a potent and specific Eg5 inhibitor with an IC50 of 0.65 μM, and can be used in the research of cancer. |
|
| DC23179 |
EGF816 mesylate |
EGF816 (Nazartinib) is a potent, irreversible, mutant-selective EGFR inhibitor with Ki and Kinact of 31 nM and 0.222 min-1, respectively. |
|
| DC23677 |
Eggmanone |
Eggmanone is a potent, selective inhibitor of PDE4 with (IC50=72 nM) that antagonizes the Hedgehog signaling pathway. |
|
| DC7728 |
EHop-016
Featured
|
EHop-016 is a novel inhibitor of Rac GTPase with IC50 of 1.1 μM for Rac1, equally potent inhibition for Rac3. |
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