| DC20277 |
Hydroxyfasudil free base
Featured
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Hydroxy-Fasudil is a metabolite of Fasudil, acting as a potent Rho-kinase inhibitor and vasodilator. |
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| DCAPI1226 |
Hydroxyflutamide (Hydroxyniphtholide) |
Hydroxyflutamide (Hydroxyniphtholide) |
|
| DC10848 |
Hydroxyhexamide
Featured
|
Hydroxyhexamide is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agents. |
|
| DCAPI1045 |
Hydroxyurea (Cytodrox) |
Hydroxyurea (Cytodrox) |
|
| DCAPI1564 |
Hyoscyamine Sulfate |
Hyoscyamine Sulfate |
|
| DC9913 |
Hypericin |
Hypericin is a photosensitive antiviral with anticancer and antidepressant agent derived from Hypericum perforatum. It can inhibit tyrosine kinases with IC50 of 7.5 μM. |
|
| DC23001 |
Hypocrellin B
Featured
|
Hypocrellin B is an apoptosis inducer. The hypocrellins are pigments isolated from the fungi Hypocrella bambusae and Shiraia bambusicola. They are used as photosensitizers for photodynamic therapy of cancer. |
|
| DC21129 |
HZ05 |
HZ05 is a potent DHODH inhibitor with IC50 of 32 nM, accumulates cancer cells in S-phase, increases p53 synthesis, and synergizes with an inhibitor of p53 degradation (Nutlin-3a) to reduce tumor growth in vivo.. |
|
| DC8834 |
HZ-1157
Featured
|
HZ-1157 is a novel potent inhibitor of HCV NS3/4A protease; Potent Dengue virus inhibitor |
|
| DC21130 |
I-191
Featured
|
I-191 is a novel potent, selective protease-activated receptor 2 (PAR2) antagonist with pIC50 of 7.2 in cell-based assays. |
|
| DC11262 |
IACS-010759
Featured
|
IACS-010759 (IACS010759) is a small molecule inhibitor of mitochondrial oxidative phosphorylation (OXPHOS), targets complex I of the mitochondrial electron transport chain. |
|
| DC12105 |
IACS-10759 Hydrochloride |
IACS-10759 is a potent inhibitor of complex I of oxidative phosphorylation (OXPHOS). |
|
| DC21131 |
IACS-4619 |
IACS-4759 potent, selective aminopyrimidine MTH1 (MutT homolog 1) inhibitor with IC50 of 0.2 nM. |
|
| DC21132 |
IACS-4759 |
IACS-4759 potent, selective aminopyrimidine MTH1 (MutT homolog 1) inhibitor with IC50 of 0.6 nM. |
|
| DC23352 |
IACS-7e |
IACS-7e is a potent TRIM24 bromodomain inhibitor with IC50 of 217.8 nM (TRIM24 ligand displacement).. |
|
| DC23361 |
IACS-9571 |
IACS-9571 is a potent, selective dual TRIM24-BRPF1 bromodomain inhibitor with Kd of 31 and 14 nM, respectively. |
|
| DC23546 |
IAXO-102 |
IAXO-102 is a novel selective TLR4 antagonist, negatively regulates non-hematopoietic TLR4 signalling and inhibits experimental AAA development. |
|
| DC21905 |
IBET151-VHL-PROTAC |
IBET151-VHL-PROTAC is a novel PROTAC.. |
|
| DC10007 |
Ibiglustat(Genz-682452）
Featured
|
Ibiglustat (Genz-682452,SAR402671), is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. |
|
| DC12341 |
Ibiglustat succinate (Venglustat (succinate); GZ/SAR402671 (succinate))
Featured
|
Ibiglustat (succinate) is a selective inhibitor of glucosylceramide synthase. |
|
| DC7635 |
IB-MECA
Featured
|
IB-MECA is a potent and selective A3 adenosine receptor agonist (Ki values are 1.1, 54 and 56 nM for A3, A1 and A2A receptors respectively). |
|
| DC21134 |
IBR2 |
IBR2 is a novel small molecule RAD51 inhibitor that specifically binds to RAD51 and disrupts the BRC repeats of BRCA2/RAD51 interaction with IC50 of 0.11 uM. |
|
| DC22112 |
IBS003031 |
IBS003031 (IBS-003031) is a novel chemical Yes-associated protein 1 (YAP1) activator, up-regulates H2B-mCherry expression at 1 and 3 uM in mCherry signal based reporter assays. |
|
| DC8983 |
Ibudilast
Featured
|
Ibudilast(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor which has been marketed for treating asthma,ibudilast (MN-166) is tested to treat acute respiratory distress syndrome (ARDS) associated with Covid-19. |
|
| DC8573 |
Ibufenac |
Ibufenac is an analog of the NSAID ibuprofen that inhibits COX-1 and -2 activity with IC50 values of 17.4 and 13.1 µM, respectively. |
|
| DC20411 |
Ibulocydine |
Ibulocydine is the prodrug of CDK inhibitor BMK-Y101, inhibits CDK7 and CDK9 with IC50 of 530 nM and 85 nM in kinase assays, respectively. |
|
| DC9163 |
Ibutilide fumarate |
Ibutilide Fumarate is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm. |
|
| DC21135 |
IC 86621
Featured
|
IC 86621 is a potent DNA-PK inhibitor with IC50 of 135 nM, also inhibits p110β (IC50=135 nM), less potent for p110α/γ/δ (IC50=880-1,400 nM). |
|
| DC21136 |
IC 87361 |
IC 87361 is a potent and selective DNA-PK inhibitor with IC50 of 34 nM, shows >50-fold selectivity over p110β. |
|
| DC23271 |
IC-9564 |
IC-9564 (AIDS033640) is a betulinic acid derivative and potent HIV entry inhibitor that blocks HIV-1 envelope-mediated membrane fusion with IC90 of 0.22 uM for NL4-3 strain. |
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