| DC20230 |
mTOR inhibitor-1
Featured
|
mTOR inhibitor-1 is a novel mTOR pathway inhibitor which can suppress cells proliferation and inducing autophagy. |
|
| DC20468 |
Mtphagy Dye |
Mtphagy Dye is a small-molecule fluorescent probe for visualizing mitophagy. |
|
| DC8240 |
3-(4,5-Dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium
Featured
|
MTS is water-soluble and used in the MTS assay. |
|
| DC22168 |
MU1210 |
MU1210 (MU-1210) is a potent and highly selective inhibitor of cdc-like kinases (CLKs) with IC50 of 51 nM (cellular BRET for CLK1). |
|
| DC22169 |
MU1300 |
MU1300 (MU-1300) is novel effective, selective modulator of the Hedgehog (Hh) pathway, suppresses Hh-dependent osteogenesis with IC50 of 300 nM in osteoblast differentiation assay using C3H10T1/2 cells, targets and binds to Smoothened (Smo) directly. |
|
| DC7205 |
Mubritinib (TAK 165)
Featured
|
Mubritinib is a potent inhibitor of the human epidermal growth factor receptor 2 (HER2) tyrosine kinase. |
|
| DC12212 |
Mulberrin (Kuwanon C) |
Mulberrin is a strong inhibitor of organic anion-transporting polypeptide 2B1 (OATP2B1)-mediated estrone-3-sulfate (E3S) uptake with an IC50 value being 1.8 ±1.5 μM. |
|
| DC23266 |
MUT-A |
MUT-A is a novel potent, HIV-1 Integrase IN-LEDGF allosteric inhibitor, shows potent anti-HIV activity with EC50 of 32 nM and 12 nM for NL4-3 or HxB2 HIV-1 strains, respectively. |
|
| DC21924 |
mutant IDH1 inhibitor VVS |
mutant IDH1 inhibitor VVS is a potent, selective mutant IDH1 inhibitor with nanomolar potency against both IDH1 R132H and IDH1 R132C, efficiently suppresses the cell-based production of D-2-HG in an HEK293 mutant embryonic kidney cell line.. |
|
| DC20258 |
MW150 (MW01-18-150SRM) |
MW150 (MW01-18-150SRM) is a selective, brain penetrant p38αMAPK, which is efficacious in diverse animal models of neurologic disorders. |
|
| DC21355 |
MW181 |
MW181 (MW01-10-181SRM) is an isoform-selective, brain-permeable, and orally bioavailable small molecule inhibitor of p38α MAPK with Ki of 184 nM, no affitnity for CK1δ. |
|
| DC21356 |
MW181 dihydrochloride |
MW181 (MW01-10-181SRM) is an isoform-selective, brain-permeable, and orally bioavailable small molecule inhibitor of p38α MAPK with Ki of 184 nM, no affitnity for CK1δ. |
|
| DC21357 |
MW181 hydrochloride |
MW181 (MW01-10-181SRM) is an isoform-selective, brain-permeable, and orally bioavailable small molecule inhibitor of p38α MAPK with Ki of 184 nM, no affitnity for CK1δ. |
|
| DC26051 |
MX1013
Featured
|
MX1013 is a dipeptide pan-caspase inhibitor that inhibits caspase-1 |
|
| DC22170 |
MX106 |
MX106 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 2.2 uM. |
|
| DC22171 |
MX107 |
MX107 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 3.1 uM. |
|
| DC21925 |
MY10 |
MY10 is a small-molecule inhibitor of RPTPβ/ζ (PTPRZ1) with IC50 of 0.1 uM, significantly increases the phosphorylation of key tyrosine residues of RPTPβ/ζ substrates involved in neuronal survival and differentiation. |
|
| DC21926 |
MY33-3 |
MY33-3 is a small-molecule inhibitor of RPTPβ/ζ (PTPRZ1) with IC50 of 0.1 uM, significantly increases the phosphorylation of key tyrosine residues of RPTPβ/ζ substrates involved in neuronal survival and differentiation. |
|
| DC9138 |
Mycophenolate Mofetil |
Mycophenolate mofetil is a prodrug for mycophenolic acid, a potent inhibitor of inosine monophosphate dehydrogenase (IC50 = 11 nM). Inhibition of this enzyme blocks de novo GTP generation as well as RNA and DNA synthesis in lymphocytes. In this way, mycop |
|
| DCAPI1127 |
Mycophenolic (Mycophenolate) |
Mycophenolic (Mycophenolate) |
|
| DC21927 |
Myokinasib |
Myokinasib is a mixed-type, selective inhibitor of Myosin Light Chain Kinase 1 (MLCK1) with IC50 of 7.9 uM, can bind to the free enzyme and the enzyme-substrate complex. |
|
| DC20469 |
myomiRs-IN-1 |
myomiRs-IN-1 is a small-molecule probe that selectively inhibits myogenic microRNAs (myomiRs) including miR-1, miR-133a, and miR-206. |
|
| DC21360 |
MZ1
Featured
|
MZ1 is a PROTAC that tethers JQ1 to a ligand for the E3 ubiquitin ligase VHL, triggers, induces degradation of the BET bromodomain BRD4. |
|
| DC22172 |
MZH29 |
MZH29 is a novel potent, selective, orally active type II FLT3 inhibitor with IC50 of 9 nM and 7 nM against FLT3-WT and FLT3-ITD, respectively. |
|
| DC8428 |
Lomitapide Mesylate |
N-(2,2,2-trifluorethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-9H-fluorene-9-carboxamide methanesulfonate |
|
| DC23254 |
N.41 |
N.41 (HIV inhibitor N.41, Vif inhibitor N.41) is a novel HIV-1 inhibitor targeting Vif-dependent degradation of human APOBEC3G (A3G) protein (IC50=2.2 uM). |
|
| DC8271 |
NSC-41589
Featured
|
N-[2-(methylsulfanyl) phenyl]acetamide. |
|
| DC21107 |
N1-hexyl-N5-benzyl-biguanide mesylate |
N1-hexyl-N5-benzyl-biguanide mesylate (HBB) is a potent and specific inhibitor of CYP3A4 AA epoxygenase activity with IC50 of 9.5 uM for inhibition of CYP3A4-mediated (±)-14,15-EET synthesis. |
|
| DC10359 |
N2-Methylguanine |
N2-Methylguanine is a modified nucleoside. N2-Methylguanine is an endogenous methylated nucleoside found in human fluids. |
|
| DC9543 |
N3PT |
N3PT(N3-pyridyl thiamine) is a potent and selective transketolase(TK) inhibitor (IC50= 22 nM for Apo-TK) both in vitro and in vivo.
|
|
