| DC10154 |
N6-(2-Phenylethyl)adenosine |
N6-(2-Phenylethyl)adenosine is a selective A1 adenosine receptor agonist. |
adenosine.gif)
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| DC23617 |
NAB-14
Featured
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NAB-14 is a potent, selective negative allosteric modulator of GluN2C/2D-containing NMDA receptors with IC50 of 580 nM, >800-fold selective over GluN2A/GluN2 receptors; inhibits triheteromeric (GluN1/GluN2A/GluN2C) NMDARs with modestly reduced potency and efficacy compared to diheteromeric (GluN1/GluN2C/GluN2C) receptors; inhibits GluN2D-mediated synaptic currents in rat subthalamic neurons and mouse hippocampal interneurons, but has no effect on synaptic transmission in hippocampal pyramidal neurons. |
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| DC8980 |
Nabumetone |
Nabumetone(BRL14777) is a non-steroidal anti-inflammatory drug and its active metabolite inhibits the COX. |
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| DC21358 |
N-acetyl lysyltyrosylcysteine amide
Featured
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N-Acetyl lysyltyrosylcysteine amide is a potent, reversible, specific, and non-toxic tripeptide inhibitor of myeloperoxidase (MPO). N-Acetyl lysyltyrosylcysteine amide effectively inhibits MPO generation of toxic oxidants in vivo. N-Acetyl lysyltyrosylcysteine amide reduces neuronal damage and preserves brain tissue and neurological function in the stroked brain. N-Acetyl lysyltyrosylcysteine amide inhibits MPO-dependent hypochlorous acid (HOCl) generation, protein nitration, and LDL oxidation. |
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| DC23924 |
N-Acetyl-Calicheamicin
Featured
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N-Acetyl-Calicheamicin is a enediyne antitumor antibiotic. |
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| DC20470 |
NAcM-COV |
NAcM-COV is a specific, irreversible small molecule inhibitor targeting N-Acetyl-UBE2M interaction with DCN1 with IC50 of 28 nM in TR-FRET assays. |
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| DC20038 |
NAcM-OPT
Featured
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NAcM-OPT is an orally bioavailable cullin neddylation 1 (DCN1) inhibitor, which potently inhibits the DCN1-UBE2M interaction. |
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| DC21444 |
Nacubactam
Featured
|
Nacubactam (OP 0595, RG 6080, RO 7079901) is a diazabicyclooctane that inhibits class A and C β-lactamases with IC50 of <1 uM, also acts as a PBP2-active antibacterial. |
|
| DC9619 |
Nafamostat (mesylate)
Featured
|
Nafamostat mesylate, a synthetic serine protease inhibitor, is an anticoagulant,showed highly potent activity against COVID-19(SARS-COV-2).
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|
| DC23132 |
Nalfurafine hydrochloride
Featured
|
Nalfurafine (TRK-820, TRK820) is potent, selective agonist of kappa-opioid receptor with Ki of 3.5 nM, 15-fold less potent for μOR and little affinity for δOR (Ki=53 and 1,200 nM, respectively). |
|
| DC23102 |
Nalfurafine
Featured
|
Nalfurafine (TRK-820, TRK820) is potent, selective agonist of kappa-opioid receptor with Ki of 3.5 nM, 15-fold less potent for μOR and little affinity for δOR (Ki=53 and 1,200 nM, respectively). |
|
| DCAPI1173 |
Nalidixic acid (NegGram) |
Nalidixic acid (NegGram) |
|
| DC20016 |
Naloxegol
Featured
|
Naloxegol is a CYP3A4 enzyme inhibitor, is a peripherally-selective opioid antagonist, for the treatment of opioid-induced constipation. |
|
| DC8492 |
Naloxegol Oxalate(NKTR-118)
Featured
|
Naloxegol is the first oral peripherally acting mu opioid receptor antagonists for opioid-induced constipation. |
|
| DC8407 |
Naloxone HCl Dihydrate
Featured
|
Naloxone HCl Dihydrate is an opioid inverse agonist drug used to counter the effects of opiate overdose. |
|
| DC20031 |
NAMPT inhibitor-linker 1 |
NAMPT inhibitor-linker 1 is a drug-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-3 consists of an NAMPT inhibitor-linker 1 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressin |
|
| DC20032 |
NAMPT inhibitor-linker 2 |
NAMPT inhibitor-linker 2 is a drug-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-4 consists of an NAMPT inhibitor-linker 2 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressin |
|
| DC22632 |
NAN-190 hydrobromide |
NAN-190 is a 5-HT1A receptor antagonist with Ki of 0.6 nM. |
|
| DC10266 |
Nandrolone decanoate
Featured
|
Nandrolone Decanoate is a mild form of an anabolic steroid. |
|
| DC10228 |
Nandrolone |
Nandrolone is a synthetic, anabolic steroid analog of testosterone. |
|
| DCAPI1368 |
Naphyrone (O-2482) |
Naphyrone (O-2482) |
|
| DC22531 |
Naquotinib |
Naquotinib (ASP-8273) is a potent, irreversible, mutant-selective inhibitor of EGFR (IC50=8-33 nM for (L858R, exon 19 deletion, L858R/T790M, and del19/T790M)). |
|
| DC22526 |
Naquotinib mesylate |
Naquotinib (ASP-8273) is a potent, irreversible, mutant-selective inhibitor of EGFR (IC50=8-33 nM for (L858R, exon 19 deletion, L858R/T790M, and del19/T790M)). |
|
| DC20700 |
Naronapride |
Naronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM. |
|
| DC21361 |
N-aryl benzimidazole |
N-aryl benzimidazole (NAB) is a small molecule that strongly and selectively protects diverse cell types from α-syn toxicity, promotes endosomal transport events dependent on the E3 ubiquitin ligase Rsp5/Nedd4 in wild-type yeast cells.. |
|
| DC23157 |
Naspm trihydrochloride
Featured
|
Naspm is a selective antagonist of Ca2+-permeable AMPA receptors, blocks GluR2-lacking AMPARs, suppresses current responses induced by kainate in type II neurons with IC50 of 0.33 uM. |
|
| DCAPI1337 |
Natamycin(Pimaricin) |
Natamycin(Pimaricin) |
|
| DC9063 |
Nateglinide |
Nateglinide is an insulin secretagog agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). |
|
| DCAPI1056 |
Nattokinase
Featured
|
Nattokinase, Natto fermentation is a potent fibrinolytic enzyme. Nattokinase can break down blood clots by directly hydrolyzing fibrin and plasmin substrate. Nattokinase can be used for the research of cardiovascular diseases. |
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| DC26021 |
6,8(2H,7H)-Isoquinolinedione,7-(acetyloxy)-5-chloro-3-(3,5-dimethyl-1,3-heptadienyl)-7-methyl- (9CI)
Featured
|
Natural product derived from fungal source. |
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