| DC34520 |
Cafestol
Featured
|
Cafestol is a natural bioactive substance in coffee, having antidiabetic properties in KKAy mice. Cafestol has been shown to exercise anti-angiogenic and anti-tumorigenic effects. |
|
| DC34521 |
AG14699 camsylate
Featured
|
Rucaparib camsylate is a potent, orally available inhibitor of poly ADP-ribose polymerase (PARP) 1 and 2. |
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| DC34522 |
DCPP |
DCPP is a potent inhibitor of DHCR7, which is known as the last enzyme in cholesterol biosynthesis. |
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| DC34523 |
Nagilactone B |
Nagilactone B is a unique selective LXR regulator which suppresses atherosclerosis in apoE-deficient mice via promotion of cholesterol efflux in macrophages. |
|
| DC34524 |
Ascorbate |
Ascorbate, also known as Ascorbicin, is a DNase I inhibitor. Ascorbate is an antioxidant which functions as a reducing agent and coenzyme in several metabolic pathways. |
|
| DC34525 |
PCN |
Pregnenolone-carbonitrile is an agonist of the rodent pregnane X receptor (PXR), inducing cytochrome P450. |
|
| DC34526 |
MitoPeroxidase 2 |
MitoEbselen-2, also known as MitoPeroxidase-2, is a radiation mitigator which reduces lipid hydroperoxides and prevents apoptotic cell death. When administered 24 hours postirradiation, MitoEbselen-2 was shown to increase the survival of mice exposed to whole body γ-irradiation. |
|
| DC34527 |
MMG11 |
MMG-11 is a potent and selective dual inhibitor of TLR2/1 and TLR2/6 signaling with low cytotoxicity. |
|
| DC34528 |
Micheliolide |
Micheliolide is a natural, irreversible activator of pyruvate kinase M2, and a suppressor of leukemia cells. |
|
| DC34529 |
Benzomalvin-A |
Benzomalvin A is a filamentous fungal secondary metabolite. |
|
| DC34530 |
RF-9 |
RF9 is a potent and selective neuropeptide FF receptor antagonist, targeting both NPFF1 and NPFF2 receptors. |
|
| DC34531 |
Orbax |
Orbifloxacin is an antibiotic which is effective against most Gram-negative bacteria, including Enterobacteriaceae and Pseudomonas. |
|
| DC34532 |
Pizotifen
Featured
|
Pizotifen is a serotonin antagonist which acts mainly at the 5-HT1, 5-HT2A, and 5HT2C receptors with some antihistamine activity. |
|
| DC34534 |
MT6378 |
MT63-78 is a direct activator of AMPK, and an inhibitor of prostate cancer growth by blocking lipogenesis. |
|
| DC34535 |
CPA |
Cyclopiazonic Acid is a natural mycotoxin which inhibits the sarcoplasmic reticulum Ca2+ pump. |
|
| DC34536 |
OKG |
Ornithine-α-ketoglutarate is a modulator of the respiratory burst via nitric oxide and polyamine generation, thereby improving immune status during stress. |
|
| DC34537 |
AG17724 |
AG-17724 is a potent peptidyl-prolyl isomerase (PPIase) Pin1 inhibitor. |
|
| DC34538 |
TerpendoleE |
Terpendole E is an atypical L5 site inhibitor. |
|
| DC34539 |
Echimidine |
Echimidine is one of the natural predominant pyrrolizidine alkaloids (PAs) found in honeys produced in Australia and New Zealand. Echimidine activates PXR and induces PXR-mediated CYP3A4 expression. |
|
| DC34540 |
Ro317549 Monohydrate |
Ro-31-7549 Monohydrate is a cell permeable, reversible, selective protein kinase C (PKC) inhibitor. |
|
| DC34541 |
Norfluoxetine hydrochloride |
Norfluoxetine hydrochloride is an active metabolite of fluoxetine. |
|
| DC34542 |
Asperulosidic Acid |
Asperulosidic Acid is a natural glycoside which inhibits both AP-1 transactivation, and cell transformation, in the mouse epidermal JB6 cell line. |
|
| DC34543 |
DAA |
Deacetylasperulosidic Acid is a natural glycoside which demonstrates antioxidant activity in vivo and in human trials. |
|
| DC34544 |
Loline |
Loline is a natural insecticidal and deterrent to a broad range of insects, including species in the Hemiptera, Coleoptera, Hymenoptera, Lepidoptera, and Blattodea orders. Loline deters species such as the bird cherry-oat aphid (genus Rhopalosiphum), large milkweed bug (Oncopeltus fasciatus), and American cockroach (Periplaneta americana), thereby protecting the host plant from insect herbivory. |
|
| DC34545 |
Momordicin I |
Momordicine I is a secondary metabolite from bitter melon (Momordica charantia L.) which significantly inhibits Spodoptera litura ovary cell line (SL-1 cell) proliferation. |
|
| DC34546 |
Grifolic acid |
Grifolic acid is a natural inhibitor of the alpha-linolenic acid (LA)-induced ERK and [Ca(2+)](i) responses in GPR120-expressing cells, and a promotor of ERK and [Ca(2+)](i) responses in GPR120-expressing cells. |
|
| DC34547 |
Adenanthin A |
Adenanthin is a natural inhibitor of thiol-dependent antioxidant enzymes, impairing the effector functions of human natural killer cells. |
|
| DC34548 |
Nothofagin |
Nothofagin is a natural anti-oxidant which inhibits endothelial protein C receptor (EPCR) shedding. Nothofagin shows diuretic, natriuretic, and potassium-sparing effects associated with prostanoids generation and muscarinic receptor activation. |
|
| DC34549 |
Nimbolide
Featured
|
Nimbolide is a natural inhibitor of pancreatic cancer growth and metastasis through ROS-mediated apoptosis. It inhibits epithelial-to-mesenchymal transition. |
|
| DC34550 |
Sulfo-Cy5-acid |
CY5 is a photoswitchable fluorescent labeling reagent. |
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