| DC35971 |
TCO-PEG4-acid |
TCO-PEG4-acid is a non-activated PEG derivative containing a TCO moiety and a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media and this reagent can be used to derivatize amine-containing molecules through a stable amide bond in the presence of activators (e.g. EDC, or HATU) . |
|
| DC35972 |
TCO-NHS ester |
TCO-NHS ester is an amine-reactive reagent containing the TCO moiety and a NHS ester. This reagent can be used to modify an amine-containing molecules. The specially formulated crystalline producty enables easy handling andan extended shelf life. TCO-NHS Ester is supplied as single axial (major) diastereomer. |
|
| DC35973 |
TCO-PEG4-NHS ester |
TCO-PEG4-NHS ester is a PEG derivative containing a TCO moiety and a NHS ester. The hydrophilic PEG spacer increases water solubility and decreases steric hindrance during ligation. This reagent can be used to label antibodies, proteins, and other primary amine-containing macromolecules with TCO moiety. |
|
| DC35974 |
TCO-PNB Ester |
TCO-PNB Ester is a biochemical. |
|
| DC35975 |
TCO-amine hydrochloride |
TCO-amine hydrochloride is a simple building block containing a TCO moiety and a free amine. This reagent can be used to derivatize carboxyl groups or activated esters (e.g. NHS esters) with the TCO moiety through a stable amide bond in the presence of of activators (e.g. EDC, or DCC). The low mass weight will add minimal spacer to modified molecules. |
|
| DC35976 |
TCO-C3-PEG3-C3-amine |
TCO-C3-PEG3-C3-amine is is a simple PEG derivative containing a TCO moiety and a free amine. This reagent can be used to derivatize carboxyl groups or activated esters (e.g. NHS esters) with the TCO moiety through a stable amide bond in the presence of of activators (e.g. EDC, or DCC). Hydrophilic PEG spacer improves water solubility. |
|
| DC35977 |
TCO-PEG4-biotin |
TCO-PEG4-biotin is a PEG Linker containing a TCO moeity. |
|
| DC35978 |
TCO-OH |
TCO-OH is a biochemical. |
|
| DC35979 |
Methyltetrazine-amine HCl |
Methyltetrazine-amine HCl salt possesses substantially improved stability compared to hydrogen substituted Tetrazine-Amine. This reagent can be used in a wider range of chemical transformations witih superior stability, enabling long-term storage in aqueous buffers. This reagent is supplied as HCl salt for improved stability and easy handling. |
|
| DC35980 |
Methyltetrazine-propylamine HCl |
Methyltetrazine-propylamine HCl salt is a PEG derivative containing methyltetrazine and is one of the most stable tetrazines commercially available. Methyl group can improve the stability of methyltetrazine-Propylamine. This reagent is supplied as HCl salt for improved stability and easy handling. |
|
| DC35981 |
Methyltetrazine-PEG4-amine HCl |
Methyltetrazine-PEG4-amine HCl salt is a PEG derivative containing a free amine and a methyltetrazine group. It is one of the most stable tetrazines commercially available. Methyl group improves the stability and hydrophilic PEG spacer increases water-solubility. This reagent is supplied as HCl salt for improved stability and easy handling. |
|
| DC35982 |
Tetrazine-Acid |
Tetrazine-Acid was found to have the fastest kinetics for bioorthogonal reactions where trans-cyclooctene (TCO) was the dienophile. The chemical stability of tetrazines is lower compared to methyltetrazines, but it is in acceptable range and thus can be applied for many applications. |
|
| DC35983 |
Methyltetrazine-acid |
Methyltetrazine-acid is a non-activated amine-reactive building block. In the presence of activators (e.g. EDC, or HATU), it can be used to deriviate amine-containing molecule via a stable amide bond. The low mass weight will add minimal spacer to modified molecules. |
|
| DC35984 |
Methyltetrazine-PEG8-acid |
Methyltetrazine-PEG8-acid is a PEG Linker |
|
| DC35985 |
Tetrazine-NHS ester |
Tetrazine-NHS ester is an NHS activated tetrazine derivative. The chemical stability of tetrazines is lower than methyltetrazines, but it is in acceptable range and thus can be applied for many applications. This reagent was found the fastest kinetics for bioorthogonal reaction with trans-cyclooctene (TCO) as the dienophile. |
|
| DC35986 |
Tetrazine-Sulfo-NHS ester |
Tetrazine-Sulfo-NHS ester is a water-soluble NHS activated tetrazine derivative. This reagent was found to have the fastest kinetics for bioorthogonal reaction with trans-cyclooctene (TCO) as the dienophile. It can be used for simple and efficient labeling of antibodies, proteins and any other primary amine-containing macromolecules with the tetrazine moiety in 100% aqueous solution. |
|
| DC35987 |
Methyltetrazine-NHS ester |
Methyltetrazine-NHS ester is an NHS actived building block containing a methyltetrazine group. It can react with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic pH to form covalent bonds. Thus, this reagent can be used for modification of amine-containing molecule in organic media and the low mass weight will add minimal spacer to modified molecules. |
|
| DC35988 |
Methyltetrazine-Sulfo-NHS ester |
Methyltetrazine-Sulfo-NHS ester is a water-soluble amine-reactive membrane impermeable labeling reagent. It is useful for applications that are intolerant of organic solvents and can be used to efficiently label antibodies, proteins, and other primary amine-containing macromolecules with the tetrazine moiety in 100% aqueous solution. |
|
| DC35989 |
Tetrazine-PEG5-NHS ester |
Tetrazine-PEG5-NHS ester is a PEG derivative containing a tetrazine group and an NHS ester. The hydrophilic PEG spacer increases water-solubility. It is one of the most reactive tetrazines commercially available. Hydrogen substituted tetrazines demonstrate exceptionally fast kinetics compared to methyl substituted tetrazines. |
|
| DC35990 |
Methyltetrazine-PEG5-NHS ester |
Methyltetrazine-PEG5-NHS ester is a PEG derivative containing a tetrazine group and an NHS ester. THe hydrophilic PEG spacer arm improves water solubility and is transferrable to the labeled molecule, reducing aggregation of labeled proteins stored in solution. The NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond. |
|
| DC35991 |
Methyltetrazine-PEG8-NHS ester |
Methyltetrazine-PEG8-NHS ester is a PEG Linker. |
|
| DC35992 |
Methyltetrazine-PEG5-alkyne |
Methyltetrazine-PEG5-alkyne is a PEG derivative containing an alkyne group and a hydrophilic PEG spacer. This reagent enables simple and efficient incorporation of a tetrazine moiety onto antibodies, cysteine-containing peptides, and other thiol-containing molecules. The alkynes can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. |
|
| DC35993 |
Methyltetrazine-PEG4-azide |
Methyltetrazine-PEG4-azide is a PEG derivative containing an azide group and a methyltetrazine moiety. The azide group enables Click Chemistry in organic solvents or aqueous media. The hydrophilic PEG spacer increases water-solubility and provides a long and flexible connection. This reagent can be used to efficiently incorporate tetrazine groups onto alkyne-modified peptides or oligonucleotides. |
|
| DC35994 |
Methyltetrazine-PEG4-maleimide |
Methyltetrazine-PEG4-maleimide is a PEG derivative containing a maleimide group and a hydrophilic PEG spacer which increases water-solubility. The maleimide group specifically and efficiently reacts with thiols to form stable thioether bonds. This reagent can be used to incorporate a tetrazine moiety onto antibodies, cysteine-containing peptides, and other thiol-containing molecules. |
|
| DC35995 |
Methyltetrazine-PEG4-NH-Boc |
Methyltetrazine-PEG4-NH-Boc is a PEG Linker. |
|
| DC35996 |
Thiol-PEG2-acid |
Thiol-PEG2-acid is a PEG derivative containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. |
|
| DC35997 |
Thiol-PEG3-acid |
Thiol-PEG3-acid is a PEG derivative containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. |
|
| DC35998 |
Thiol-PEG4-acid |
Thiol-PEG4-acid is a PEG derivative containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. |
|
| DC35999 |
Thiol-PEG8-acid |
Thiol-PEG8-acid is a PEG derivative containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. |
|
| DC36000 |
Thiol-PEG3-t-butyl ester |
Thiol-PEG3-t-butyl ester is a PEG derivative containing a thiol group and a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. |
|
