DC36760 |
Ambroxol |
Ambroxol is a metabolite of Bromhexine that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride. |
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DC36762 |
Abbott 36581 |
Butamirate, particularly Butamirate citrate, is a cough suppressant that works by acting centrally through the receptors in the brainstem. It has a very beneficial effect, because it reduces the resistance in the airways by inhibiting bronchospasm and anti-inflammatory effect. |
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DC36763 |
Phostriecin |
Phostriecin, also known as Sultriecin, is an antifungal and antitumor antibiotic from Streptomyces roseiscleroticus. |
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DC36764 |
Carbutamide |
Carbutamide is a sulfonylurea antidiabetic agent with similar actions and uses to chlorpropamide. |
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DC36765 |
Niceritrol |
Niceritrol is an ester of nicotinic acid that lowers cholesterol and triglycerides in total plasma and in the VLD- and LD-lipoprotein fractions. |
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DC36766 |
Xenalipin |
Xenalipin is a hypolipidemic that reduces blood cholesterol and triglycerides in rats. |
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DC36767 |
Methisazone |
Methisazone is an antiviral agent effective against pox viruses. |
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DC36768 |
BW245C |
BW245C has potent platelet anti-aggregating actions following parenteral or oral administration which makes this hydantoin a potentially-useful anti-thrombotic prostaglandin analogue. |
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DC36769 |
Phenobarbital |
Phenobarbital is a barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations. Phenobarbital is discontinued. |
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DC36770 |
Carazolol |
Carazolol is a beta1/beta2 adrenoceptor antagonist of high potency used in the treatment of hypertension. Its affinity for the beta 3-adrenoceptor was determined in Chinese hamster ovary cells transfected with the gene of the human or the murine beta 3-adrenoceptor. Carazolol is recognized with a nanomolar affinity, which positions it among the best ligands for beta 3-adrenoceptors. |
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DC36771 |
Cefapirin |
Cefapirin is an antibiotic effective against gram-negative and gram-positive organisms. |
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DC36772 |
Ocinaplon |
Ocinaplon appears to be a well-tolerated and effective treatment for GAD. It produces a rapid onset of anxiolytic action absent the side effects (e.g., dizziness, sedation) typically reported following anxiolytic doses of benzodiazepines. |
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DC36773 |
Leucovorin |
Leucovorin is the active metabolite of folic acid. Leucovorin is used principally as its calcium salt as an antidote to folic acid antagonists which block the conversion of folic acid to folinic acid. |
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DC36774 |
Paramethasone |
Paramethasone is a glucocorticoid with the general properties of corticosteroids. It has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than Hydrocortisone with supplementary Fludrocortisone. |
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DC36775 |
Curcumenol |
Curcumenol is a sesquiterpene isolated from Curcuma zedoaria is known to possess a variety of health and medicinal values which includes neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. |
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DC36776 |
Cynaropicrin |
Cynaropicrin is the first plant natural product with in vivo activity against Trypanosoma brucei. |
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DC36777 |
Cyclobendazole |
Cyclobendazole is an antihelmintic; benzimidazole derivative related to mebendazole. |
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DC36778 |
Cyheptamide |
Cyheptamide is an anticonvulsant. |
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DC36779 |
Alminoprofen |
Alminoprofen is a nonsteroidal anti-inflammatory agent that was found to significantly suppress passive anaphylactic bronchoconstrictions at 30 mg/kg given intraduodenally, while ibuprofen did not at the same doses. |
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DC36780 |
Levcromakalim |
Levcromakalim, also known as Lemakalim, is an anti-asthmatic, antihypertensive, and potassium-ATP channel opener. |
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DC36781 |
Oxethazaine |
Oxethazaine is a surface anesthetic used mainly orally in chronic gastritis & heartburn to analgize the gastric mucosa. |
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DC36782 |
Spiroxatrine |
Spiroxatrine is a potent dopamine antagonist that most likely functions as an agonist at the 5-HT1A receptor. This compound is similar to buspirone in that it has a prominent dopamine antagonist component and has been found to produce greater anxiolytic effects when combined with buspirone. |
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DC36783 |
Esmolol |
Esmolol is a short acting hyperselective β-adrenergic blocker effective in blunting adrenergic response to several perioperative stimuli and so it might interfere in the effect of the anesthetic drugs on the brain. Esmolol is effective not only in attenuating intraoperative hemodynamic changes related to sympathetic overdrive but also in minimizing significant propofol and sevoflurane requirements without compromising the hemodynamic status. |
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DC36784 |
Piribedil |
Piribedil is a dopamine D2 agonist. It is used in the treatment of Parkinson disease, particularly for alleviation of tremor. It has also been used for circulatory disorders and in other applications as a D2 agonist. |
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DC36785 |
Syrosingopine |
Syrosingopine has been found to potentiate the anticancer activity of widely used diabetic drug metformin by sensitizing cancer cells to metformin. |
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DC36787 |
Chlorhexidine |
Chlorhexidine is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque. |
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DC36788 |
Norgestrel |
Norgestrel is a synthetic progestational agent with actions similar to those of PROGESTERONE. This racemic or (±)-form has about half the potency of the levo form (LEVONORGESTREL). Norgestrel is used as a contraceptive, ovulation inhibitor, and for the control of menstrual disorders and endometriosis. |
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DC36789 |
Sulindac sulfone
Featured
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Sulindac sulfone is an mTORC1 pathway inhibitor and a metabolite of Sulindac. Sulindac sulfone inhibits colon cancer cell growth and induces cell cycle arrest. Sulindac sulfone is used in cancer research. |
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DC36790 |
Fucosterol |
Fucosterol has been reported to have antioxidant, antidiabetic, and anti-inflammatory effects. In one study, fucosterol exhibited a protective effect on LPS-induced acute lung injury with a possible mechanism inhibiting NF-κB activation, thereby inhibiting LPS-induced inflammatory response. |
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DC36791 |
Fasudil
Featured
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Fasudil, a Rho-kinase inhibitor, has been shown to reduce portal venous pressure in cirrhotic rats. |
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