| DC36792 |
Clemastine |
Clemastine is an FDA approved antimuscarinic compound that has been found to rescue impaired myelination and reverse social avoidance behavior in mice. |
|
| DC36793 |
XY 018 |
XY 018 is a RORγ antagonist that suppresses androgen receptor expression in prostate cancer cell lines and inhibits growth of tumors in androgen receptor-positive xenograft models. |
|
| DC36794 |
Cinnamamide |
Cinnamamide is an amide of trans-cinnamic acid and a metabolite of Streptomyces that reduced tumor weight in a mouse model of C26 murine colon carcinoma, in vivo. |
|
| DC36795 |
Helecin |
Helecin is the O-glucoside of salicylaldehyde, which is a key precursor to a variety chelating agents. |
|
| DC36796 |
Phenibut |
Phenibut, a GABA analogue, is a central nervous system depressant with anxiolytic and sedative effects. |
|
| DC36797 |
WEHI-539 HCl |
WEHI-539 has high affinity (IC50=1.1 nM) and selectivity for BCL-XL and potently kills cells by selectively antagonizing its prosurvival activity. It has more than a 400-fold higher affinity for BCL-XL versus other prosurvival BCL-2 family members. |
|
| DC36798 |
Cefazedone |
Cefazedone is a semisynthetic first-generation cephalosporin with antibacterial activity. |
|
| DC36799 |
Iproniazid |
Iproniazid is a non-selective, irreversible monoamine oxidase (MAO) inhibitor (MAOI) that is used as an antidepressive agent. |
|
| DC36800 |
A 127722 |
A 127722 is highly potent and a selective ETA endothelin receptor antagonist (IC50 values are 0.11 nM and 98 nM for human ETA and ETB receptors, respectively)that attenuates hypoxia-induced pulmonary hypertension in rats. |
|
| DC36801 |
Metipranolol hydrochloride |
Metipranolol (hydrochloride) is a non-selective β-adrenergic receptor (β-AR) antagonist. Formulations containing metipranolol have been used in the treatment of elevated IOP in patients with ocular hypertension or glaucoma. |
|
| DC36802 |
Lymecycline |
Lymecycline is a semisynthetic antibiotic related to TETRACYCLINE. |
|
| DC36803 |
AI3-17254 |
Sulfaquinoxaline is an antiprotozoal agent used to combat coccidial infections of swine, cattle, fowl, and other veterinary animals. Also used in controlling outbreaks of fowl typhoid and fowl cholera and in treatment of infectious enteritis. |
|
| DC36804 |
Bay f 4797 |
Azidamfenicol is a broad-spectrum chloramphenicol-like antibiotic that is active against Gram-negative and Gram-positive bacteria. It inhibits ribosomal peptidyltransferase. |
|
| DC36805 |
Cycloechinulin |
Cycloechinulin is a diketopiperazine fungal metabolite originally isolated from A. ochraceus. It reduces weight gain of corn earworms by 33% compared to controls when used at a dose of 100 ppm in the diet. |
|
| DC36806 |
Ginkgetin |
Ginkgetin is a biflavonoid that has been isolated from G. biloba and has diverse biological activities, including pro-apoptotic, antiproliferative, anti-inflammatory, anti-atherosclerosis, and neuroprotective properties. |
|
| DC36807 |
Valpromide |
Valpromide is an antiepileptic drug, derivative of Valproic acid (VPA), used as a mood-stabilizer in bipolar disorder. |
|
| DC36808 |
Cloflucarban |
Cloflucarban is a disinfectant agent. |
|
| DC36809 |
TC KHNS 11
Featured
|
TC KHNS 11 is a potent and selective PI 3-kinase δ inhibitor that is orally bioavailable. |
|
| DC36810 |
ML 351
Featured
|
ML 351 is a selective 12/15 LOX inhibitor that is active in vivo. |
|
| DC36811 |
3CAI |
3CAI is an inhibitor of Akt1 and Akt2 with anticancer activity. |
|
| DC36813 |
Leriglitazone |
Leriglitazone is a peroxisome proliferator activated receptor (PPAR) gamma
agonist. |
|
| DC36814 |
TL4-12
Featured
|
TL4-12 is a potent MAP4K2 (GCK) inhibitor that inhibits IL-1 and TGFβ-induced p38 MAPK phosphorylation, in vitro. |
|
| DC36815 |
Flonicamid |
Flonicamid is a pyridinecarboxamide insecticide. Flonicamid inhibits aphid (M. persicae) salivation and sap ingestion during feeding on Japanese radish leaves. It induces toxicity in the aphid species A. gossypii, R. padi, S. graminum, and L. erysimi and rats. Formulations containing flonicamid have been used for the control of pest insects in agriculture. |
|
| DC36816 |
Spirotetramat |
Spirotetramat is an insecticide active against C. pyri nymphs in vitro. |
|
| DC36817 |
Allolactose |
Allolactose is a disaccharide similar to lactose. It is an inducer of the lac operon in Escherichia coli and many other enteric bacteria. |
|
| DC36818 |
Idramantone |
Idramantone is an immunostimulant, a derivative of adamantine, and used in the treatment of pulmonary tuberculosis patients. |
|
| DC36819 |
AZ 5704 |
AZ 5704 is a potent and selective ATM kinase inhibitor. |
|
| DC36821 |
KT 1 |
KT 1 decreased aortic pressure, renal blood flow, left ventricular enddiastolic pressure and resistances of total peripheral, vertebral, coronary and renal vasculatures and increased aortic blood flow, vertebral blood flow, coronary blood flow, peak positive left ventricular dP/dt and heart rate in anesthetized open-chest dogs. |
|
| DC36822 |
Fludioxonil |
Fludioxonil is a phenylpyrrole fungicide that inhibits the growth of B. cinerea isolates from strawberry and blackberry crops. |
|
| DC36823 |
Trifloxystrobin |
Trifloxystrobin is a fungicide that inhibits the growth of R. solani isolates from sugar beet crops. |
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