DC37910 |
PD-166793
Featured
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PD-166793 is a cell-permeable biphenylsulfonylvaline compound that acts as a potent inhibitor against MMP-2, -3, and -13 (IC50 = 47, 12, and 8 nM, respectively) and a weaker inhibitor against AMP deaminase (20% inhibition at 0.1 μM), MMP-1, -7, -9, and -14 (IC50 = 6.1, 7.2, 7.9, and 0.24 μM, respectively). Shown to offer therapeutic benefits in vivo in various animal models of heart failure and diabetes. |
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DC37911 |
Fructosylvaline |
Fructosylvaline is an Amadori compound having the potential to alter cellular adhesion, inhibit cancer metastasis and induce apoptosis. |
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DC37912 |
Valsartan benzyl ester |
Valsartan benzyl ester is a Valsartan intermediate. |
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DC37913 |
N-Ethyl valacyclovir |
Valacyclovir Related Compound D is a bioactive chemical. |
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DC37914 |
Vasicinone |
Vasicinone is a quinazoline alkaloid that can be isolated from A. vasica leaves and demonstrates bronchodilatory activity. It also is reported to possess antioxidant activity in nitric oxide and ABTS radical scavenging assays. |
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DC37915 |
Vasicine |
Vasicine is an alkaloid. |
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DC37916 |
(R)-Efavirenz |
Efavirenz, (R)- is a nonnucleoside HIV-1 reverse transcriptase inhibitor. Efavirenz, (R)- is an antiviral. |
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DC37917 |
Butalamine |
Butalamine is a vasodilator (peripheral) with local anesthetic effects. Butalamine has been shown to inhibit state 3 respiration and decrease ADP/O in rat liver. |
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DC37918 |
Dequalinium chloride |
Dequalinium chloride is a topical bacteriostat that is available as various salts. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration. |
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DC37919 |
(Z)-Abienol |
(Z)-Abienol is a bicyclic diterpene, and is the major labdanoid present in some oriental tobacco cultivars, where it constitutes a precursor of important flavours and aromas. |
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DC37920 |
Labetalol |
Labetalol is a mixed alpha/beta adrenergic antagonist that is used to treat high blood pressure. It can be given intravenously in severe hypertensive situations, or by mouth for long term hypertension management. Studies suggest that the pharmacokinetics of labetalol are significantly affected by the common CYP2C19 polymorphisms. |
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DC37921 |
Fenpropimorph |
Fenpropimorph is a small moluecule fungicide. |
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DC37922 |
Hydrocortisone butyrate |
Hydrocortisone butyrate is a topical corticosteroid use to treat a variety of dermatological conditions. It acts as an antiinflammatory, antiproliferative and immunosuppresive agent. |
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DC37923 |
Benoxinate hydrochloride |
Benoxinate HCl is a local anesthetic used in ophthalmology to numb the surface of the eye for a variety of procedures. |
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DC37924 |
Carbetamide |
Carbetamide is a mitosis inhibitor. |
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DC37925 |
Magnesium lactate |
Magnesium lactate is a buffering agent and magnesium donor |
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DC37926 |
Lactamide |
Lactamide is used in 2M solution as hyperosmotic agent on ciliary epithelium. |
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DC37927 |
Lactitol |
Lactitol is a gastrointestinal agent. |
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DC37928 |
Maclurin |
Maclurin is isolated from Maclura pomifera. Maclurin is composed of two isoforms (isolectins); some sequence similarity to jacalin; potent non-specific blood-group hemagglutinin. |
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DC37929 |
(R)-Lamivudine sulfoxide |
Lamivudine sulfoxide, (R)- is a metabolite of Lamivudine; a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B. |
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DC37930 |
Lamivudine impurity A RS |
Lamivudine impurity A RS is a bioactive chemical. |
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DC37931 |
Illudin S
Featured
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Illudin S is a fungal sesquiterpene that, through their unique DNA alkylating actions, have anticancer potential. Illudin S is a cytotoxic illudin that is converted, intracellularly, to metabolites that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM). T-lymphocyte leukemia CEM cells that are resistant to doxorubicin (Item No. 15007), epipodophyllotoxins, and 1-β-D-arabinofuranosylcytosine display only 2-fold increased resistance to illudin S. Illudin S metabolites induce DNA damage that is not repaired by the processes that counter conventional DNA alkylating agents. |
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DC37932 |
Anazolene sodium |
Anazolene sodium is a diagnostic Aid (Blood Volume and Cardiac Output Determination). |
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DC37933 |
Digitoxin |
Digitoxin is a cardiac glycoside sometimes used in place of DIGOXIN. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. |
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DC37934 |
Digoxigenin |
Digoxigenin is a cardenolide which is the aglycon of digoxin. Can be obtained by hydrolysis of digoxin or from Digitalis orientalis L. and Digitalis lanata Ehrh. |
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DC37935 |
Purpurea glycoside B |
Purpurea glycoside B is a cardiac glycoside. |
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DC37936 |
Purpurea glycoside A |
Purpurea glycoside A is a cardiac glycoside analog. |
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DC37937 |
Cloethocarb |
Cloethocarb is a molluscicide. |
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DC37938 |
Alginic acid |
Alginic acid is a suitable reagent used to study the in-vitro and in-vivo mitogenic activity of alginates. It is suitable for use in the spectrophotometric determination of transparent exopolymer particles by dye-binding assay. |
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DC37939 |
Fluometuron |
Fluometuron is an herbicide. In the United States it was approved for use on cotton and sugarcane crops in 1974, but since 1986 is only approved for use on cotton. |
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