| DC45679 |
2-Amino-2-deoxyglucose hydrochloride |
2-Amino-2-deoxyglucose hydrochloride is a hexosamine hydrochloride can be used in the synthesis of cyclopropene-modified hexosamine derivative Ac4GlcNCyoc and Ac4GalNCyoc. |
|
| DC45680 |
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate |
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat produces a relapsing-remitting neurological disease with extensive plaque-like demyelination. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate induces strong T and B cell responses and is highly encephalitogenic. |
|
| DC45681 |
Histone H3 (1-35) (TFA) |
Histone H3 (1-35) TFA is a 35-residue peptide of histone H3. Histone H3 is one of the five main histones involved in the structure of chromatin in eukaryotic cells. |
|
| DC45682 |
DLPLTFGGGTK TFA |
DLPLTFGGGTK (TFA) is a surrogate peptide for pembrolizumab identification. |
|
| DC45683 |
Mad1 (6-21) |
Mad1 (6-21) is the 6-21 fragment of Mad1 protein. Mad1 (6-21) binds to mammalian Sin3A PAH2 with a Kd of ~29 nM. |
|
| DC45684 |
Mad1 (6-21) (TFA) |
Mad1 (6-21) TFA is the 6-21 fragment of Mad1 protein. Mad1 (6-21) TFA binds to mammalian Sin3A PAH2 with a Kd of ~29 nM. |
|
| DC45685 |
Polyphyllin F |
Polyphyllin F is a diosgenyl saponin that can be found in Paris polyphylla. |
|
| DC45757 |
AG-636
Featured
|
AG-636 is an orally available inhibitor of dihydroorotate dehydrogenase (DHODH) with potential antineoplastic activity. |
|
| DC45758 |
Revumenib
Featured
|
SNDX-5613 is a potent and selective inhibitor of menin-MLL binding with a Ki of 0.15 nM. SNDX-5613 shows anti-proliferative activity against multiple cell lines harboring MLLr translocations (MV4;11, RS4;11, MOLM-13, KOPN-8) with IC50 values ranging from 10-20 nM. |
|
| DC45759 |
EFdA-TP |
EFdA-TP is a potent nucleoside reverse transcriptase (RT) inhibitor. EFdA-TP inhibits RT-catalyzed DNA synthesis as an effective immediate or delayed chain terminator (ICT or DCT). EFdA-TP inhibits HIV-1 RT with multiple mechanisms. |
|
| DC45760 |
EFdA-TP tetraammonium |
EFdA-TP tetraammonium is a potent nucleoside reverse transcriptase (RT) inhibitor. EFdA-TP tetraammonium inhibits RT-catalyzed DNA synthesis as an effective immediate or delayed chain terminator (ICT or DCT). EFdA-TP tetraammonium inhibits HIV-1 RT with multiple mechanisms. |
|
| DC45761 |
EFdA-TP tetrasodium |
EFdA-TP tetrasodium is a potent nucleoside reverse transcriptase (RT) inhibitor. EFdA-TP tetrasodium inhibits RT-catalyzed DNA synthesis as an effective immediate or delayed chain terminator (ICT or DCT). EFdA-TP tetrasodium inhibits HIV-1 RT with multiple mechanisms. |
|
| DC45764 |
TAT peptide TFA |
TAT peptide (TFA) is a cell penetrating peptide (GRKKRRQRRRPQ) derived from the trans-activating transcriptional activator (Tat) from HIV-1. |
|
| DC45765 |
DSTYSLSSTLTLSK TFA |
DSTYSLSSTLTLSK TFA is a generic human peptide and can be used for infliximab quantitative detection. Infliximab (Avakine) is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α. |
|
| DC45767 |
[Des-Tyr1]-Met-Enkephalin |
[Des-Tyr1]-Met-Enkephalin, a tetrapeptide, is a degradationproduct of enkephalins. |
|
| DC45772 |
TAK-683 acetate |
TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0.96 nM and 1.6 nM for human and rat, respectively. TAK-683 acetate depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer. |
|
| DC45781 |
FNC-TP |
FNC-TP is the intracellular active form of FNC. FNC is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. |
|
| DC45782 |
GGTI-2154 |
GGTI-2154 is a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I), with an IC50 of 21 nM. GGTI-2154 shows more than 200-fold selectivity for GGTase I over FTase (IC50=5600 nM). GGTI-2154 can be used for the research of cancer. |
|
| DC45817 |
FNC-TP trisodium |
FNC-TP trisodium is the intracellular active form of FNC. FNC is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. |
|
| DC45828 |
Homoeriodictyol 7-O-β-D-glucoside |
Homoeriodictyol 7-O-β-D-glucoside is a natural platelet-activating factor (PAF) antagonist. Homoeriodictyol 7-O-β-D-glucoside inhibits human and rabbit platelet aggregation induced by PAF, with an IC50 of 0.8 μM. |
|
| DC45836 |
Rubinaphthin A |
Rubinaphthin A is a naphthohydroquinone that can be found in the roots of Rubia yunnanensis. Rubinaphthin A exhibits inhibitory activity against tobacco mosaic virus (TMV). |
|
| DC45840 |
DHODH-IN-16 |
DHODH-IN-16 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH. |
|
| DC45843 |
(Rac)-EC5026 |
(Rac)-EC5026 ((Rac)-BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) extracted from patent WO2019156991A1, has a Ki of 0.06 nM. (Rac)-EC5026 can be used for the research of Parkinson's disease and dementia with Lewy Bodies (DLB). |
|
| DC45879 |
23-epi-26-Deoxyactein |
23-epi-26-Deoxyactein is a natural and orally active anti-obesity and anti-cancer compound. |
|
| DC45891 |
Verbascose |
Verbascose, an alacto-oligosac-charides (GOS), has potent immunostimulatory activity. Verbascose acts as a potential natural immunomodulatory agent. |
|
| DC45893 |
Prosaikogenin F |
Prosaikogenin F is a monoglycoside with anticancer and hemolytic properties. |
|
| DC45899 |
Ilexgenin A |
Ilexgenin A is a pentacyclic triterpenoid, which extracted from Ilex hainanensis Merr. Ilexgenin A can be used for the research of inflammation and cancer. |
|
| DC45906 |
Emodin 6-O-β-D-glucoside |
Emodin-6-O-β-D-glucoside (Glucoemodin) is an active compound from Reynoutria japonica. Emodin-6-O-β-D-glucoside shows potent anti-inflammatory and barrier protective effects. Emodin-6-O-β-D-glucoside can be used for the research of diabetic complications and atherosclerosis. |
|
| DC45907 |
Niga-ichigoside F1 |
Niga-ichigoside F1, an orally active ursane triterpenoid, has antihyperlipidemic and antioxidant activities. Niga-ichigoside F1 can prevent high-fat diet (HFD)-induced hepatic steatosis. |
|
| DC45914 |
Telaglenastat hydrochloride |
Telaglenastat (CB-839) hydrochloride is a first-in-class, selective, reversible and orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat hydrochloride selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2. The IC50s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat hydrochloride inudces autophagy and has antitumor activity. |
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