| DC45843 |
(Rac)-EC5026 |
(Rac)-EC5026 ((Rac)-BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) extracted from patent WO2019156991A1, has a Ki of 0.06 nM. (Rac)-EC5026 can be used for the research of Parkinson's disease and dementia with Lewy Bodies (DLB). |
|
| DC45879 |
23-epi-26-Deoxyactein |
23-epi-26-Deoxyactein is a natural and orally active anti-obesity and anti-cancer compound. |
|
| DC45891 |
Verbascose |
Verbascose, an alacto-oligosac-charides (GOS), has potent immunostimulatory activity. Verbascose acts as a potential natural immunomodulatory agent. |
|
| DC45893 |
Prosaikogenin F |
Prosaikogenin F is a monoglycoside with anticancer and hemolytic properties. |
|
| DC45899 |
Ilexgenin A |
Ilexgenin A is a pentacyclic triterpenoid, which extracted from Ilex hainanensis Merr. Ilexgenin A can be used for the research of inflammation and cancer. |
|
| DC45906 |
Emodin 6-O-β-D-glucoside |
Emodin-6-O-β-D-glucoside (Glucoemodin) is an active compound from Reynoutria japonica. Emodin-6-O-β-D-glucoside shows potent anti-inflammatory and barrier protective effects. Emodin-6-O-β-D-glucoside can be used for the research of diabetic complications and atherosclerosis. |
|
| DC45907 |
Niga-ichigoside F1 |
Niga-ichigoside F1, an orally active ursane triterpenoid, has antihyperlipidemic and antioxidant activities. Niga-ichigoside F1 can prevent high-fat diet (HFD)-induced hepatic steatosis. |
|
| DC45914 |
Telaglenastat hydrochloride |
Telaglenastat (CB-839) hydrochloride is a first-in-class, selective, reversible and orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat hydrochloride selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2. The IC50s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat hydrochloride inudces autophagy and has antitumor activity. |
|
| DC45925 |
Soyasapogenol D |
Soyasapogenol D is a methyl-trimethylsilyl derivative of the sapogenin. |
|
| DC45928 |
1,2-Dihydrotanshinone |
1,2-Dihydrotanshinone (1,2-Dihydrotanshinquinone) is an abietane diterpene. 1,2-Dihydrotanshinone inhibits the formation of the pathogenic complex formed between (CUG)n-RNA and the splicing-factor muscleblind-like 1 (MBNL1). 1,2-Dihydrotanshinone can be used for the research of myotonic dystrophy type 1. |
|
| DC45937 |
Crocin IV |
Crocin IV (Dicrocin), a crocetin glycoside, is a carotenoid pigment. Crocin IV has potent antioxidant activity. |
|
| DC45945 |
Guattegaumerine |
Guattegaumerine is a bisbenzylisoquinoline alkaloid with antimitotic, cytotoxic and neuroprotective activities. |
|
| DC45949 |
Heishuixiecaoline A |
Heishuixiecaoline A is a germacrane-type sesquiterpenoid. Heishuixiecaoline A shows protective effect on the neurotoxicity of PC12 cells induced by Aβ25-35. |
|
| DC45950 |
Hellebrigenol |
Hellebrigenol is a metabolite of bufadienolides with antitumor activity. |
|
| DC45952 |
Isorhamnetin 3-O-β-D-glucose-7-O-β-D-gentiobioside |
Isorhamnetin 3-O-β-D-glucose-7-O-β-D-gentiobioside is a bioactive constituent that can be found in the seeds of Lepidium apetalum Willd. Isorhamnetin 3-O-β-D-glucose-7-O-β-D-gentiobioside exhibits significant triglyceride (TG)-lowering effects in HepG2 cells. |
|
| DC45955 |
Loureiriol |
Loureiriol is a homoisoflavonoid with weak anticancer effects. |
|
| DC45958 |
Malvidin chloride |
Malvidin (chloride) is a bioactive compound isolated from Oryza sativacv. Heugjinjubyeo. Malvidin shows cytotoxicity through the arrest of the G2/M phase of cell cycle and induction of apoptosis. Malvidin can be used for the research of cancer. |
|
| DC45961 |
Methyl (E)-cinnamate |
Methyl (E)-cinnamate (EMC), a phytochemical constituent isolated from Alpinia katsumadai Hayata, is a natural flavor compound with anti-inflammatory properties. Methyl (E)-cinnamate is widely used in the food and commodity industry. |
|
| DC45963 |
Neolancerin |
Neolancerin is a natural product with weak cytotoxic activity against HL-60 cells. |
|
| DC45969 |
S-(4-Hydroxybenzyl)glutathione |
S-(4-Hydroxybenzyl)glutathione is a glutathione derivative. S-(4-Hydroxybenzyl)glutathione inhibits the in vitro binding of kainic acid to brain glutamate receptors, with an IC50 of 2 μM. |
|
| DC45972 |
Tarasaponin IV |
Tarasaponin IV, as an oleanane-type triterpene saponin, is isolated from the bark of Aralia elata. Tarasaponin IV can be used for the research of cancer. |
|
| DC45973 |
Tetrahydroxymethoxychalcone |
Tetrahydroxymethoxychalcone is a phenolic and flavonoid compound. Tetrahydroxymethoxychalcone is found to enhance myoblast proliferation and differentiation. Tetrahydroxymethoxychalcone plays important roles in myogenesis and muscle regeneration. |
|
| DC45975 |
Tumulosic acid |
Tumulosic acid, a triterpenoid, inhibits KLK5 protease activity (IC50= 14.84 μM). Tumulosic acid suppresses the proteolytic processing of LL-37 in keratinocytes at ≤10 μM. |
|
| DC45978 |
γ-Asarone |
γ-Asarone, a phenylpropene, shows strong correlation with the biological activities (anti-oxidative, anti-inflammatory and neurotrophic effects). |
|
| DC45985 |
Salvianolic acid Y |
Salvianolic acid Y is a phenolic acid with the same planar structure as Salvianolic acid B. Salvianolic acid Y rescues cell injury by H2O2. |
|
| DC45987 |
Pelargonidin 3-galactoside chloride |
Pelargonidin 3-galactoside chloride is a major anthocyanin with anticancer effects. Pelargonidin 3-galactoside chloride inhibits α-glucosidase. |
|
| DC45988 |
Echinocystic acid 28-O-β-D-glucoside |
Echinocystic acid 28-O-β-D-glucoside is a metabolite of Echinocystic acid by microbial oxidation and glucosidation. Echinocystic acid 28-O-β-D-glucoside is a tissue factor pathway inhibitor, with an IC50 of 10.61 nM. |
|
| DC45991 |
Luteolin-7-O-α-L-arabinopyranosyl (1→6)-β-D-glucopyranoside |
Luteolin-7-O-α-L-arabinopyranosyl (1→6)-β-D-glucopyranoside is a flavonoid with antiradical activity. |
|
| DC45992 |
Quercetin 3-O-(6''-O-galloyl)-β-D-glucoside |
Quercetin 3-O-(6''-O-galloyl)-β-D-glucoside (Tellimoside) is a flavonol glycoside with strong inhibitory activity against the growth of Microcystis aeruginosa. |
|
| DC45994 |
Eupalinolide H |
Eupalinolide H, a sesquiterpene lactone, has the potential to be used as natural anti-inflammatory agent. |
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