| DC46335 |
Isobyakangelicol |
Isobyakangelicol is a coumarin that can be found in the roots of Angelica dahurica. Isobyakangelicol inhibits the growth of HeLa and HepG2 cells, with IC50s of 70.04 μM and 17.97 μM. |
|
| DC46337 |
3X FLAG peptide |
3X FLAG Peptide is a synthetic peptide with a 3-time repeated DYKXXD motif. |
|
| DC46342 |
Protein E7(43-62) TFA |
Protein E7(43-62) TFA is an E7-derived peptide with anti-tumor effects (short peptide spanning the 43th to 62th amino acid residues in the E7 protein). |
|
| DC46344 |
FATP1-IN-1 |
FATP1-IN-1 is a fatty acid transport protein 1 (FATP1) inhibitor. FATP1-IN-1 is an inhibition of recombinant human or mouse acyl-CoA synthetase activity of FATP1, with the IC50 values of 0.046 μM or 0.60 μM, respectively. |
|
| DC46351 |
Ac2-12 TFA |
Ac2-12 TFA, an annexin/lipocortin 1 (LC1)-mimetic peptide, inhibit neutrophil extravasation. Ac2-12 TFA has antimigratory action and inhibits recruitment of neutrophils in experimental inflammation models. |
|
| DC46354 |
Neopanaxadiol |
Neopanaxadiol, an aglycone of protopanaxadiol type ginsenosides, has the potential for Alzheimer's disease research. |
|
| DC46355 |
γ-Terpinene |
γ-Terpinene, a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly. γ-Terpinene has potent antinociception activity. |
|
| DC46360 |
A 71915 |
A 71915 is a highly potent and competitive natriuretic peptide receptor A (ANP, NPRA) antagonist (pKi= 9.18). A 71915 displaces [125I]ANP dose dependently, with a Ki of 0.65 nM. A71915( pA2= 9.48) against rat ANP-induced cGMP production in NB-OK-1 cells. |
|
| DC46370 |
VGSC blocker-1 |
VGSC blocker-1 is a potent and small molecule blocker of neonatal isoform of the VGSC subtype, Nav1.5 (nNav1.5). VGSC blocker-1 blocks INa peak currents 34.9% at 1 μM and inhibits cell invasion 0.3% at 1 μM in human breast cancer cell line MDA-MB-231, without affecting the cell viability. |
|
| DC46383 |
Mycalolide B |
Mycalolide-B is a specific inhibitor of actomyosin ATPase isolated from marine sponge. Mycalolide-B inhibits ATP-induced contraction and Mg2+-ATPase activity in the absence of Ca2+. |
|
| DC46411 |
AB-680 ammonium |
AB-680 ammonium is a highly potent, reversible and selective inhibitor of CD73 (an ecto-nucleotidase), with a Ki of 4.9 pM for hCD73, displays >10,000-fold selectivity over related ecto-nucleotidases CD39. Anti-tumor activity. |
|
| DC46419 |
11R-VIVIT TFA
Featured
|
11R-VIVIT TFA is a cell-permeable nuclear factor of activated T cells (NFAT) inhibitor. 11R-VIVIT TFA can be used for the research of podocyte and diabetic nephropathy. |
|
| DC46422 |
GSK9027 |
GSK9027, as a non-steroidal glucocorticoid receptor (GR) agonist, behaves as a partial agonist on the 2×glucocorticoid response element (GRE) reporter system, and achieves intrinsic activities relative to dexamethasone. |
|
| DC46471 |
RP101988
Featured
|
RP101988, the major active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC50s of 0.19 nM and 32.8 nM for S1PR1 and S1PR5, respectivlely. |
|
| DC46494 |
TAK-683 TFA |
TAK-683 TFA is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK-683 TFA is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0.96 nM and 1.6 nM for human and rat, respectively. TAK-683 TFA depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer. |
|
| DC46513 |
Visnagin |
Visnagin, an antioxidant furanocoumarin derivative, possess anti-inflammatory and analgesic properties. Visnagin has substantial potential to prevent Cerulein induced acute pancreatitis (AP). Visnagin possess promising vasodilator effects in vascular smooth muscles. |
|
| DC46514 |
Cinnamtannin A2 |
Cinnamtannin A2, a tetrameric procyanidin, can increases GLP-1 and insulin secretion in mice. Cinnamtannin A2 could upregulate the expression of corticotrophin releasing hormone. Cinnamtannin A2 exhibits antioxidant, anti-diabetic and nephroprotective effect. |
|
| DC46523 |
D-JBD19 TFA |
D-JBD19 TFA is a non-permeable peptide. D-JBD19 TFA has neuroprotective effects. |
|
| DC46524 |
HAIYPRH hydrochloride
Featured
|
HAIYPRH hydrochloride, a targeting ligand, can specially bind to transferrin receptor (TfR). HAIYPRH hydrochloride can mediate the transport of nanocarriers across the blood-brain barrier. |
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|
| DC46533 |
TCS 184 TFA |
TCS 184 TFA is a polypeptide fragment. |
|
| DC46535 |
THK-5475(THK 5475)
Featured
|
THK-5475(THK5475) is a precursor of THK-5470, a monoamine oxidase-B(MAO-B) imaging probe, could be used for neurological diseases study (from patent EP2019-846498). |
|
| DC46536 |
Ammonium sulphate,≥99.0%,AR |
Ammonium sulphate,≥99.0%,AR is an inorganic sulfate salt used for molecular biology. |
|
| DC46537 |
I-bu-rG Phosphoramidite |
I-bu-rG Phosphoramidite is a phosphinamide monomer which can be used in the synthesis of nucleotides and nucleic acids. |
|
| DC46546 |
8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen |
8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen is a coumarin that can be found in Heracleum pyrenaicum Lam. |
|
| DC46549 |
A-71915 TFA |
A-71915 (TFA) is a selective inhibitor of ANP receptor (atrial natriuretic peptide-receptor), induces apoptosis and decreases insulin secretion in RINm5F pancreatic β-cells. |
|
| DC46550 |
BDC2.5 mimotope 1040-31 TFA |
BDC2.5 mimotope 1040-31 TFA, a BDC2.5 TCR reactive peptide, is a strong agonistic peptide for diabetogenic T cell clone BDC2.5, and the 1040-31 peptide is specific for BDC 2.5 TCR Tg+ T cells. |
|
| DC46551 |
BMf-BH3 |
BMf-BH3 belongs to the Bcl-2 apoptosis mediator family. BH3-only protein, Bmf is a key molecule for histone deacetylase (HDAC) inhibitors mediated enhancing effect on ionizing radiation-induced cell death. |
|
| DC46552 |
GRK2i TFA |
GRK2i TFA is a GRK2 inhibitory polypeptide that specifically inhibitsGβγ activation of GRK2. GRK2i TFA corresponds to the Gβγ-binding domain and acts as a cellular Gβγ antagonist. |
|
| DC46553 |
Nuclear pore complex protein Nup98 (315-360) |
Nuclear pore complex protein Nup98 (315-360) is the 315-360 fragment part of the nuclear pore complex (NPC) protein. |
|
| DC46554 |
sgp91 ds-tat Peptide 2, scrambled |
sgp91 ds-tat Peptide 2, scrambled is a scrambled sequence of NADPH oxidase inhibitor gp91 ds-tat peptide. |
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