DC50045 |
Deoxybrevianamide E |
Deoxybrevianamide E, an indole alkaloid, is a biosynthetic precursor for advanced metabolites isolated from the marine-derived Aspergillus sp.. |
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DC50171 |
CD73-IN-6 |
CD73-IN-6 is a CD73 inhibitor extracted from patent WO2022007677A1 compound 2. CD73-IN-6 can be used for the research of cancer. |
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DC50230 |
GLS-1-IN-1 |
GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor. GLS-1-IN-1 shows inhibitory effect against Hep G2, MCF 7, and MCF 10A cells. |
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DC50276 |
Glemanserin |
Glemanserin (MDL11939) is a potent and selective antagonist for serotonin receptor 5-HT2A (Ki=2.89, 0.54 and 2.5 nM for rat 5-HT2A, rabbit 5-HT2A and human 5-HT2A, respectively). |
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DC50277 |
Citalopram |
Citalopram is marketed as a racemate mixture of the S(+)-enantiomer and R(-)-enantiomer and the active S(+)-enantiomer (Escitalopram) that possess inhibitory effects. Citalopram is an antidepressant and enhances serotoninergic neurotransmission through potent and selective inhibition of serotonin reuptake (selective serotonin reuptake inhibitor). |
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DC50286 |
(-)-(E)-α-Atlantone |
(-)-(E)-α-Atlantone is a volatile constituent of Artemisia vestita oil. |
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DC50287 |
Methyl jasmonate |
Methyl jasmonate is a phytohormone involved in plant defenses under stress conditions. Methyl jasmonate can improve antioxidant properties of blueberry leaf extracts (mainly anthocyanins), and decrease the viability and migration capacity of AGS cells. Anticarcinogenic activity. |
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DC50288 |
4-epi-Withaferin A |
4-epi-Withaferin A (compound 28) is the analogue of Withaferin A. 4-epi-Withaferin A enhances cytotoxicity and cytoprotective heat-shock-inducing activity (HSA). 4-epi-Withaferin A has the potential for the research of protein aggregation-associated diseases by stimulating cellular defense mechanisms. |
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DC50289 |
MC 304 |
MC 304 is a β-resorcylate isolated from cultures of Phanerochaete chrysosporium. MC 304 has antibacterial activity. MC 304 shows a stimulatory effect on root elongation of Lepidium satiuum. |
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DC50290 |
Agistatin D |
Agistatin D is a pyranacetal originally isolated from a Fusarium sp. that inhibits the cholesterol biosynthesis. |
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DC50291 |
Roridin A |
Roridin A is an inhibitor of pollen development in Arabidopsis thaliana. Roridin A is isolated from the fungus Cylindrocarpon sp. Roridin A inhibits the pollen development at concentrations of 2 μM. |
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DC50292 |
Aquastatin A |
Aquastatin A is an inhibitor of mammalian adenosine triphosphatases. Aquastatin A is isolated from a fungus identified as Fusarium aquaeductuum. Aquastatin A inhibits Na+/K(+)-ATPase with an IC50 value of 7.1 μM, and H+/K(+)-ATPase with an apparent IC50 value of 6.2 μM. |
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DC50293 |
Carbolactone |
Carbolactone is a biologically active metabolite from fungi. |
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DC50294 |
Pixinol |
Pixinol, a natural glycoside, shows cytotoxicity against the human lung carcinoma GLC4 and adenocarcinoma COLO 320 cell lines (IC50=71 µM and 43 µM, respectively). |
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DC50295 |
4-Methyl withaferin A |
4-Methyl withaferin A is a withaferin A-analogue with anti-tumor activity. |
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DC50296 |
4,27-Dimethyl withaferin A |
4,27-Dimethyl withaferin A is a synthetic analog of withanolide natural products. 4,27-Dimethyl withaferin A has the potential for the research of neurodegenerative diseases (extracted from patent WO2015077780A1). |
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DC50297 |
Terrelumamide A |
Terrelumamide A is a lumazine-containing peptide. Terrelumamide A is isolated from the culture broth of the marine-derived fungus Aspergillus terreus. Terrelumamide A exhibits pharmacological activity by improving insulin sensitivity. Terrelumamide A has the potential in the application of DNA sequence recognition. |
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DC50298 |
Trypacidin |
Trypacidin is the conidia-bound metabolite with antiprotozoal activity. Trypacidin has a protective function against phagocytes both in the environment and during the infection process. |
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DC50299 |
epi-Progoitrin |
epi-Progoitrin is the major thioglucoside of Crambe abyssinica seed. |
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DC50300 |
Stachybotrysin B |
Stachybotrysin B is a phenylspirodrimane derivative. Stachybotrysin B is isolated from Stachybotrys chartarum CGMCC 3.5365. |
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DC50301 |
Diallyl disulfide |
Diallyl disulfide inhibits human squalene monooxygenase with an IC50 of 400 μM for squalene epoxidation. |
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DC50302 |
2,3-Dihydro-3-methoxywithaferin A |
2,3-Dihydro-3-methoxywithaferin A is an analogue of 2,3-dihydrowithaferin-A. 2,3-Dihydro-3-methoxywithaferin A inhibits proiiferation of P388 cells. |
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DC50303 |
Methyl tetracosanoate |
Methyl tetracosanoate is used as an analytical standard in chromatographic assays. |
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DC50304 |
Gluconapin potassium |
Gluconapin potassium is the precursor of sulforaphane. Sulforaphane is a potent anti-cancer isothiocyanate. |
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DC50305 |
OB3 |
OB3, a derivative of Leptin, show more effective than leptin in reducing obesity and diabetes in mouse models. OB3 can reduce Leptin-related inflammation and proliferation in hepatocellular carcinoma cells. |
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DC50306 |
Hortein |
Hortein is a natural product from the fungus Hortaea werneckii associated with the sponge Aplysina aerophoba. |
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DC50307 |
Tajixanthone |
Tajixanthone is the fungus metabolite from Aspergillus variecolor. |
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DC50308 |
Mycestericin C |
Mycestericin C is a compound isolated from the culture broth of Mycelia sterilia ATCC 20349. Mycestericin C suppresses the proliferation of lymphocytes in the mouse allogeneic mixed lymphocyte reaction. |
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DC50309 |
Muristerone A |
Muristerone A is a phytoecdysteroid analog of ecdysone and a potent agonist of ecdysteroid receptor with a Kd of 1 nM. |
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DC50310 |
(-)-(E)-Guggulsterone |
(-)-(E)-Guggulsterone is the metabolite of Z-guggulsterone. Guggulsterone is an active constituent of guggulipid, an ayurvedic drug derived from Commiphora mukul. Guggulsterone has hypolipidaemic activity. |
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