| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC73900 | AKST1220 | AKST1220 is a potent, specific leukotriene A4 hydrolase (LTA4H) inhibitor, improves hippocampal dependent memory. |
|
| DC73901 | Alrefimotide | Alrefimotide (Telomerase reverse transcriptase 660-689 peptide antigen). |
|
| DC73902 | AM9053 (AM 9053) | AM9053 (AM 9053) is a potent, selective inhibitor of N-Acylethanolamine acid amidase (NAAA) with IC50 of 30 nM, with limited effect on FAAH activity (IC50>100 uM). |
|
| DC73903 | Antabactin | Antabactin (ANT) is a highly potent pan-abscisic acid (ABA) receptor antagonist with EC50 of 760 nM and picomolar dissociation constant, disrupts signaling by preventing receptor-PP2C interactions. |
|
| DC73904 | AP736 | AP736 is a damantyl benzylbenzamide derivative with anti-melanogenic effects in melanocytes in vitro, acts via the downregulation of tyrosinase, TRP-1 and MITF expression. |
|
| DC73905 | APC655 | APC655 is a potent activator of protein folding and unfolded protein response (UPR) modulator, APC655 activates ATF6 pathway and chaperone expression. |
|
| DC73906 | AQIM-I | AQIM-I is a highly potent small molecule survivin inhibitor by targeting ILF3/NF110, binds to ILF3/NF110 with KD value of 163 nM in SPR assays, has broad-spectrum antitumor activity. |
|
| DC73907 | ARL67156 | ARL67156 (FPL 67156) is a selective inhibitor of ecto-ATPase, ARL67156 is a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively. |
|
| DC73908 | ART899 | ART899 (ART-899) is a potent, specific allosteric inhibitor of DNA polymerase theta (Polθ), specifically inhibits Polθ MMEJ activity with IC50 of 180 nM, shows with improved in vivo stability compared to ART558. |
|
| DC73909 | ARUK2001607 Featured | ARUK2001607 is a potent, selective and brain penetrant PI5P4Kγ inhibitor with binding KD of 7.1 nM, pIC50 of 7.1 (PI5P4Kγ+). |
|
| DC73910 | ARUK200282 | ARUK200282 is a potent, isoform-selective PI5P4Kα inhibitor with pIC50 of 8.0, selective over PI5P4Kβ and PI5P4Kγ. |
|
| DC73911 | ARUK2002821 | ARUK2002821 is a potent, selective PI5P4Kα inhibitor with pIC50 of 8.0, >1000-fold selective over PI5P4Kγ. |
|
| DC73912 | ARUK2007145 | ARUK2007145 is a potent, selective and cell-active PI5P4Kα/γ dual inhibitor with pIC50 of 7.3/8.1, resepctively, shows no activity against PI5P4Kβ. |
|
| DC73913 | ASB17061 | ASB17061 (ASB-17061) is an orally active, selective chymase inhibitor with IC50 of 0.03 uM and 0.02 uM for mMCP-4 and human chymase, respecitvely. |
|
| DC73914 | ASN 90 | ASN90 is a potent, selective, substrate-competitive O-GlcNAcase (OGA) inhibitor with IC50 of 10.2 nM. |
|
| DC73915 | ASP7967 | ASP7967 (ASP-7967) is a cell-permeable and low-toxic compound of RNA aptamer AC17-4 with SPR binding Kd of 12 nM, activates gene expression (>10-fold) in aptazyme-based riboswitches with EC50 of 2.3 uM. |
|
| DC73916 | AZ13792138 | AZ13792138 is a highly potent, selective inhibitor of MTH1 (NUDT1) with Kd/IC50 of 0.4/0.5 nM. |
|
| DC73917 | BCL3ANT | BCL3ANT (NSC-659509) is a small molecule inhibitor of Bcl-3-mediated cyclin D1 expression, reduces cyclin D1 luciferase activity in Bcl-3-overexpressing melanoma cells with IC50 of 40.4 uM. |
|
| DC73918 | BD442618 | BD442618 (BD 442618) is a potent small-molecule GPR52 agonist. |
|
| DC73919 | BD50265 | BD50265 (BD 50265) is a potent small-molecule GPR52 agonist. |
|
| DC73920 | BI-0955 | BI-0955 is an inactive HSD17B13 control compound for BI-3231. |
|
| DC73921 | BI-9466 | BI-9466 (BI 9466) is the negative control of NSD3-PWWP1 domain chemical probe BI-9321. |
|
| DC73922 | BiTud | BiTud is a bivalent inhibitor against TDRD3 with binding Kd of 6 uM for tandem Tudor chimera, blocks the recruitment of TDRD3 by the two methylated arginines of G3BP1, suppress the phase separation of methylated G3BP1, TDRD3, and RNAs, and in turn inhibit |
|
| DC73923 | BK697 | BK697 is a small molecule targeting FIRΔexon2, potentially interacts with FIRΔexon2, significantly suppresses the FIRΔexon2 expression and inhibits tumor cell growth and several rRNA expressions. |
|
| DC73924 | BNZ-1 | BNZ-1 (BNZ132-1-40) is a pegylated peptide, BNZ132-1 conjugated with methoxy-PEG40 maleimide molecule via a specific linker (CGSGG), specifically binds the γc receptor to selectively block IL-2, IL-15 and IL-9 signaling. |
|
| DC73925 | BNZ132-1 | BNZ132-1 (QITISILSQINRVFHEKFI) is a specific peptide inhibitor for the IL-2/IL-15 subfamily, directly binds to the γc molecule (CD132). |
|
| DC73926 | BR102910 | BR102910 (BR 102910) is a novel potent, selective, oral fibroblast activation protein (FAP) inhibitor with IC50 of 1 nM. |
|
| DC73927 | BRD4780 | BRD4780 is a small molecule that releases MUC1-fs from TMED9-enriched compartments and promotes its anterograde trafficking to the lysosome, directly binds to TMED9. |
|
| DC73928 | BRD8518 | BRD8518 is a specific small molecule TRIB1 inducer, modulates expression of the key genes involved in VLDL production and in LDL clearance in HepG2 cells. |
|
| DC73929 | BRM011 | BRM011 (dual BRM and BRG1 inhibitor 11) is a potent, selective, allosteric dual BRM and BRG1 inhibitor with IC50 of <5 nM for both. |
|
