| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC73930 | Butaselen | Butaselen is a small molecule inhibitor of thioredoxin reductase (TrxR)/thioredoxin (Trx) with anti-tumor activity, inhibits the growth of various human cancer cell lines. |
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| DC73931 | C105SR | C105SR is small-molecule cyclophilin inhibitor with IC50 of 5 nM for inhibition of CypD PPIase activity and 9 nM for mitochondrial swelling. |
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| DC73932 | C10M | C10M is a small molecule inhibitor of C-reactive protein (CRP), inhibits the binding of pCRP to the physiological ligand phosphocholine (PC) with IC50 of 1.5 mM in ELISA assays. |
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| DC73933 | C902 Featured | C902 is a small-molecule inhibitor targeting LIN28-let-7 interaction, shows dose-dependent inhibition in an EMSA validation assay with IC50 of 5 uM. |
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| DC73934 | Calmirasone1 | Calmirasone1 (Calmirasone 1) is a novel and potent covalent calmodulin (CaM) inhibitor with Kd of 0.87 uM. |
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| DC73935 | CARD8 activator CQ31 | CARD8 activator CQ31 is a small molecule that selectively activates CARD8. |
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| DC73936 | CASK chemical probe 18 | CASK chemical probe 18 is a highly potent and selective CASK inhibitor with IC50 of 22 nM. |
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| DC73937 | CB253 | CB253 is a small molecule that selectively binds the hairpin form of r(G4C2)exp, inhibiting mechanisms that drive c9ALS/FTD pathobiology. |
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| DC73938 | CBK034026C | CBK034026C is a small molecule targeting metabolic vulnerabilities caused by N-acetyltransferase 2 (NAT2) activity, exhibits specific toxicity towards colorectal cancer (CRC) cells with high NAT2 activity. |
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| DC73939 | CBLC000 | CBLC000 (CBL0100) is a small molecule histone chaperone FACT inhibitor, activates p53 and inhibits NF-κB with EC50 of 0.06 and 0.03 uM in cell-based p53 and NF-κB reporter assays, respecitvely. |
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| DC73940 | CC-410 | CC-410 (CC410) is a potent, specific inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 of 1.6 uM (human NNMT). |
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| DC73941 | CHD1Li 11 | CHD1Li 11 (CHD1L inhibitor 11) is a small molecule inhibitor of chromodomain helicase DNA-binding protein 1 like (CHD1L) with IC50 of 4.57 uM. |
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| DC73942 | CIB-3b | CIB-3b is a small molecule inhibitor disrupting the TRBP-Dicer interaction, suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells. |
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| DC73943 | Cimlanod | Cimlanod is a second-generation nitroxyl (HNO) donor.. |
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| DC73944 | CK147 | CK147 (CK-147) is a potent CD4 down-modulator with IC50 of 63 nM, inhibits Sec61-dependent cotranslational translocation of huCD4 in vitro. |
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| DC73945 | CKi-4 | Creatine kinase inhibitor CKi-4 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.3 uM, depletes creatine phosphagen energetics in cells. |
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| DC73946 | CKi-6 | CKi-6 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.6 uM, depletes creatine phosphagen energetics in cells. |
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| DC73947 | Cl-NIO | Cl-NIO is a potent, selective inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) with Ki of 1.3 uM, > 500-fold selectivity against arginase and endothelial nitric oxide synthase. |
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| DC73948 | CMP05 Featured | CMP05 (Endosomolytic compound CMP05) is a novel endosomolytic small-molecule compound that exhibits higher transfection efficiency/ability to induce endosomal escape of oligonucleotides (ONs) than current compounds such as chloroquine. |
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| DC73949 | CMP05-7 | CMP05-7 (Endosomolytic compound CMP05-7) is a novel endosomolytic small-molecule compound that exhibits higher transfection efficiency/ability to induce endosomal escape of oligonucleotides (ONs) than current compounds such as chloroquine. |
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| DC73950 | CNS-11 | CNS-11 is a small molecules capable of disassembling preformed alpha-synuclein fibrils, may exert it's disaggregating effects on the N terminus of the fibril core. |
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| DC73951 | CNS-11g | CNS-11g is a small molecules capable of disassembling preformed alpha-synuclein fibrils, may exert it's disaggregating effects on the N terminus of the fibril core. |
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| DC73952 | Coproporphyrin III | Coproporphyrin III is a diffusible small molecule porphyrin excreted by human-associated Propionibacterium spp., induces Staphylococcus aureus aggregation and biofilm formation, also induces S. aureus to form a plasma-independent surface-attached biofilm. |
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| DC73953 | CPAG-1 Featured | CPAG-1 (PGRMC2 activator CPAG-1) is a small-molecule activator of PGRMC2. CPAG-1 treatment had no effect on weight or food intake but treated mice had reduced fasting glycemia and insulin levels. CPAG-1 decreased Rev-Erbα protein in BAT of CPAG-1-treated mice. CPAG-1 also significantly increased labile heme in the nucleus of brown adipocytes from CPAG-1-treated mice within 4 days of treatment. |
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| DC73954 | CPR1-B | CPR1-B is a longer-acting phenylhexanamide mitofusin activator, increases mitochondrial motility in MFN2 T105M expressing mouse DRGs with EC50 of 3.3 nM (Emax=89%). |
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| DC73955 | CQ211 | CQ211 is a potent, highly selective RIOK2 inhibitor with Kd of 6.1 nM, shows excellent selectivity to RIOK2 in both enzymatic and cellular assays. |
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| DC73956 | CRS0540 | CRS0540 is a potent, selective PolC DNA polymerase inhibitor that has demonstrated good in vitro and in vivo activity against Listeria monocytogenes. |
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| DC73957 | CT-179 | CT-179 is a small molecule inhibitor of protein transcription factor OLIG2 (Oligodendrocyte transcription factor 2), CT-179 is a putative disruptor of OLIG2 homodimerization. |
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| DC73958 | CU-76 | CU-76 (cGAS inhibitor CU-76) is a small-molecule human cGAS (hcGAS) inhibitor with IC50 of 0.24 uM. |
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| DC73959 | CW3388 | CW3388 (CW-3388, CW3388) is a potent, cell-active Δ8,7-sterol isomerase (EBP) inhibitor, shows near-maximal effects on oligodendrocyte formation at 110 nM. |
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