| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC74050 | KIO-100 | KIO-100 (PP-001) is a novel potent, specific small molecule inhibitor of DHODH with IC50 of <4 nM, 150-fold higher potency than leflunomide (IC50 of 650 nM). |
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| DC74051 | KL101 | KL101 (KL 101) is a isoform-selective small molecule stabilizer of Cryptochrome 1 (CRY1). |
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| DC74052 | KP-1019 | A ruthenium complex anticancer agent that is useful for metastatic tumors and cis-platin resistant tumors. |
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| DC74053 | KP-1339 | A promising ruthenium anticancer compound that blocks angiogenesis, endothelial cell proliferation and migration stimulated by VEGF or NO donor agent. |
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| DC74054 | KRP-6 | KRP-6 is a potent and highly selective macrophage migration inhibitory factor (MIF) ketonase inhibitor with IC50 of 4.31 uM, significantly reduces MIF-induced neutrophil migration. |
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| DC74055 | KS10076 | KS10076 is a metal chelator with potent anti-cancer cytotoxicity, destabilizes STAT3 by elevating ROS, shows remarkable cytotoxic efficacy in 100 cancer cell lines of different types with IC50 of <1 uM. |
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| DC74056 | KVS0001 | KVS0001 is a specific and bioavailable small molecule inhibitor of SMG1 kinase, disrupts nonsense mediated decay (NMD). |
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| DC74057 | KZR-8445 | KZR-8445 (KZR8445) is a cyclic depsipeptide, client-selective Sec61 inhibitor with IC50 of 100 nM, targets the Sec61 translocon and selectively modulate Sec61-mediated protein biogenesis. |
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| DC74058 | L6H21 | L6H21 is an orally active, potent and specific myeloid differentiation 2 (MD-2) inhibitor with binding KD value of 33.3 uM, blocks the formation of the LPS-TLR4/MD-2 complex. |
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| DC74059 | LI-2242 | LI-2242 is a potent pan-IP6K inhibitor with IC50 of with IC50 of 31, 42 and 8.1 nM for IP6K1, IP6K2 and IP6K3, respectively. |
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| DC74060 | LP-403812 | LP-403812 is a specific small molecule inhibitor of mammalian proline transporter (PROT), inhibits PROT-mediated proline uptake with IC50 of 0.1 uM on both recombinant human and mouse PROT. |
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| DC74061 | LSALT peptide | Metablok (LSALT peptide) is a specific DPEP1-binding peptide and nonenzymatic dipeptidase-1 (DPEP-1) inhibitor. |
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| DC74062 | L-Thyroxine sodium salt pentahydrate | A manufactured form of the thyroid hormone thyroxine (T4) that typically used to treat hypothyroidism. |
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| DC74063 | LX-6171 | LX-6171 is a small molecule proline transporter (SLC6A7) inhibitor with potential for treating cognitive and other disorders. |
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| DC74064 | Macrocyclic peptide D4-2 Featured | Macrocyclic peptide D4-2 is a macrocyclic peptide consisting of 15 amino acids that binds to the ectodomain of mouse SIRPα (Kd=10 nM, IgV-B6 SIRPα) and efficiently blocks CD47-SIRPα interaction in an allosteric manner (IC50=0.18 uM). |
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| DC74065 | MASM7 | MASM7 is a small molecule activator of mitochondrial fusion via mitofusins (MFN1 and MFN2), concentration-responsively increases mitochondrial aspect ratio (Mito AR) in MEFs with EC50 of 75 nM, directly and specifically modulates MFN1/2 fusogenic activity |
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| DC74066 | MCI-100 | MCI-100 is a small molecule that displays greater potency than sulindac to protect RPE cells against oxidative damage, with lacked significant COX inhibitory activity, MCI-100 is more active than sulindac in protecting cells against oxidative damage. |
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| DC74068 | MEISi-1 | MEISi-1 (MEIS inhibitor 1) is a specific small molecule inhibitor of MEIS1 (Meis1), significantly inhibits MEIS1 protein activity in MEIS-luc reporter assays at 0.1 uM, modulates hematopoietic stem cell (HSC) activity. |
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| DC74069 | Melatonin Biotin | Melatonin Biotin is compound conjuncted melatonin with biotin.. |
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| DC74070 | Methyl-β-cyclodextrin | A cholesterol depleting agent that shows antitumor activity both in vitro and in vivo. |
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| DC74071 | MIDI | MIDI (Mitochondrial division inhibitor) is a potent, covalent mitochondrial fission inhibitor, interacts with DRP1-C367 to block mitochondrial fission. |
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| DC74072 | Mito-C | Mito-C is a specific chemical compound targeting NEETs proteins, induces mitochondrial network fragmentation and represses dengue viral replication. |
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| DC74073 | MitoCKi | MitoCKi (Creatine kinase inhibitor CKi-26) is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 185 nM, depletes creatine phosphagen energetics in cells. |
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| DC74074 | Mito-LND | Mito-LND (Mito-lonidamine) is a tumor-selective inhibitor of oxidative phosphorylation with IC50 of 1.2 and 2.4 uM for mitochondrial complexes I and II, respectively, impacts the activity of mitochondrial complexes, ROS generation and peroxiredoxin oxidat |
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| DC74075 | ML181 | ML181 (CYM50557) is a potent and selective GPR7 (Neuropeptides B/W receptor 1, NPBW1) antagonist probe with IC50 of 270 nM for inhibition of NPW-induced GPR7 activation. |
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| DC74076 | MLS000544460 | MLS000544460 (EYA2i) is a specific, allosteric inhibitor of Eya2 phosphatase with IC50 of 4.1 uM, KD of 2.0 uM, does not bind Eya3 ED, Eya1 and Eya4 ED. |
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| DC74077 | MM0299 | MM0299 (MM 0299) is a potent, selective inhibitor of lanosterol synthase (LSS, competition EC50=1.97 nM) with anti-proliferative activity, inhibits Mut6 cell growth (IC50=18.2 nM) and induces the synthesis of 24(S),25-epoxycholesterol (EPC). |
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| DC74078 | MM0299 analog 13 | MM0299 analog 13 (MM 0299 derivative 13) is a potent, selective, orally bioavailable, brain-penetrant inhibitor of lanosterol synthase (LSS, competition EC50=28.7 nM) with anti-proliferative activity. |
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| DC74079 | MN132.0262 | MN132.0262 is a small molecule, dual inhibitor of A3G (APOBEC3G, IC50=20 uM). |
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| DC74080 | MN256.0102 | MN256.0102 is a small-molecule APOBEC3G DNA cytosine deaminase inhibitor with IC50 of 3.9 uM. |
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