Cat. No. | Product name | CAS No. |
DC23348 |
BI 894999
BI 894999 is a novel potent, selective BET inhibitor with IC50 of 5 and 41 nM for BRD4-BD1 and BRD4-BD2 bromodomains, respectively. |
1660117-38-3 |
DC23560 |
BI01383298
Featured
BI01383298 (BI-01383298) is a potent, specific sodium-citrate co-transporter SLC13A5 (NaCT, INDY), highly selective over other family members and other transporters.. |
2227549-00-8 |
DC12406 |
BI-0314
Featured
BI-0314 (BI0314) is an allosteric activator of protein tyrosine phosphatase non-receptor type 5 (PTPN5, STEP) with potency of 56% at 500 uM, displays no activity against hPTP1B and hTCPTP. |
2244560-46-9 |
DC23049 |
BI1002494
BI1002494 (BI-1002494) is a novel, potent, and selective spleen tyrosine kinase (SYK) inhibitor with enzyme IC50 of 30 nM, cell IC50 of 7 nM (FcεR1-mediated histamine release in human monocyte-derived mast cells, in the presence of 0.1% albumin). |
1319738-39-0 |
DC20775 |
BI-1347
Featured
BI-1347 is a potent, selective inhibitor of CDK8/cyclinC with IC50 of 1 nM. |
2163056-91-3 |
DC22020 |
BI-1388
BI-1388 is a potent, specific, macrocyclic inhibitor of HCV NS3 protease, inhibits viral replication for various HCV genotypes and for resistant mutants D168V and R155K. |
1309952-03-1 |
DC20777 |
BI-1935
BI-1935 is a potent, selective small molecule inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 7 nM. |
940954-41-6 |
DC22022 |
BI-1950
BI-1950 is a potent, selective LFA-1 antagonist that inhibits the binding of LFA-1 to ICAM-1 with Kd value of 9 nM. |
1159724-42-1 |
DC22023 |
BI-3663
BI-3663 (BI 3663) is a cereblon-based degrader (PROTAC) of Focal adhesion tyrosine kinase (PTK2/FAK) with a median DC50 of 30 nM to >80% across a panel of eleven HCC cell lines. |
|
DC20779 |
BI-3802
Featured
BI-3802 (BI3802) is a highly potent and efficacious BCL6 degrader that potently inhibits the interaction of the BTB/POZ domain of BCL6 with several co-repressors in vitro with IC50 of <3 nM. |
2166387-65-9 |
DC23310 |
BI-3812
Featured
BI-3812 is potent and efficacious BCL6 inhibitor, inhibiting the BTB domain of BCL6, with an IC50 of ≤3 nM; BI-3812 has antitumor activity. |
2166387-64-8 |
DC22024 |
BI-4394
BI-4394 is a highly potent, selective MMP-13 inhibitor with IC50 of 1 nM, displays >1,000 fold selectivity against nine other MMP isoforms (MMP2/14, IC50=18/8.3 uM). |
1222173-37-6 |
DC22310 |
BI-4464
Featured
BI-4464 (BI 4464) is a potent, highly selective, ATP competitive inhibitor of Focal adhesion tyrosine kinase (PTK2/FAK) with IC50 of 17 nM.. |
1227948-02-8 |
DC20784 |
BI8622
BI8622 (BI-8622) is a specific small molecule inhibitor of the HUWE1 ubiquitin ligase with IC50 of 3.1 uM, does not inhibit the activity of other HECT-domain ubiquitin ligases (HECW2, NEDD4,UBA1 and UbcH5b). |
1875036-74-0 |
DC20785 |
BI8626
BI8626 (BI-8626) is a specific, small molecule inhibitor of the HUWE1 ubiquitin ligase with IC50 of 0.9 uM, does not inhibit the activity of other HECT-domain ubiquitin ligases (HECW2, NEDD4,UBA1 and UbcH5b, IC50>50 uM). |
1875036-75-1 |
DC23608 |
BI-9627
BI-9627 is a potent, selective inhibitor of sodium-hydrogen exchanger isoform 1 (NHE1) with pHi change IC50 of 6 nM, displays >30-fold selectivity against NHE2 and with no measurable inhibitory activity against the NHE3 isoform. |
1204329-34-9 |
DC12567 |
BI-9667
BI-9667 (BI9667) is a potent, selective CCR1 antagonist.. |
1295298-26-8 |
DC22027 |
BI-99179
BI-99179 is a potent and selective inhibitor of type I fatty acid synthase (FAS) with IC50 of 79 nM. |
1291779-76-4 |
DC4206 |
Biapenem
Biapenem is a carbapenem antibiotic. |
120410-24-4 |
DC23366 |
biBET
biBET is a potent, selective, bivalent inhibitor of BET bromodomains with pKd of 8.3/7.3/11 for BRD4(1)/BRD4(2)/BRD4(1,2), respectively. |
2059110-46-0 |
DC20788 |
BIBO-3304
Featured
BIBO 3304 is a potent, selective, nonpeptide neuropeptide Y Y1 receptor antagonist with IC50 of 0.38 and 0.72 nM for human and the rat Y1 receptor, respectively. |
191868-14-1 |
DC12211 |
BIBR 1087 SE (Desethyl Dabigatran Etexilate)
BIBR 1087 SE is an intermediate metabolite of dabigatran etexilate. |
212321-78-3 |