Cat. No. | Product name | CAS No. |
DC20789 |
BIBU1361
BIBU1361 is a potent, selective, orally active EGFR inhibitor with IC50 of 3 nM, shows weak activity against HER2 (IC50=280 nM) and no inhibition on IGF1R, HGFR, Src, and VEGFR2 (IC50>10 uM). |
793726-84-8 |
DC20790 |
BIBU1361 dihydrochloride
BIBU1361 is a potent, selective, orally active EGFR inhibitor with IC50 of 3 nM, shows weak activity against HER2 (IC50=280 nM) and no inhibition on IGF1R, HGFR, Src, and VEGFR2 (IC50>10 uM). |
1643609-75-9 |
DC1024 |
Afatinib (BIBW2992)
Featured
BIBW2992 (Afatinib, Tomtovok, Tovok) irreversibly inhibits EGFR/HER2 including EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively. |
439081-18-2 |
DC20791 |
BIIL260
BIIL260 is the active metabolite of BIIL284, shows high affinity to LTB4 receptor on isolated human neutrophil cell membranes with Ki of 1.7 nM. |
204974-93-6 |
DC20793 |
BILH-434
BILH-434 is a potent HPV11 E1/E2/DNA complex inhibitor that binds to the transactivation domain (TAD) of E2 protein with a Kd of 40 nM, has an IC50 of 180 nM in the E1-E2-ori complex formation assay.. |
760169-28-6 |
DC22281 |
Bilobalide
Featured
Bilobalide is a sesquiterpene lactone which is found in extracts of G. biloba. |
33570-04-6 |
DC6801 |
Bindarit
Featured
Bindarit exhibits selective inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8. |
130641-38-2 |
DC20795 |
BIO 8898
BIO 8898 is a synthetic, CD40-CD154 co-stimulatory interaction inhibitor that inhibits the TNF family cytokine CD40L binding to CD40-Ig with a potency of IC50=25 uM. |
402564-79-8 |
DC11069 |
BIO124
BIO124 (BIO-124) is a modest inhibitor of the PICK1-GluA2 interaction with IC50 of 0.51 uM in FP assays, binds to the PDZ domain of PICK1.. |
|
DC12401 |
BIO922
BIO922 (BIO 922, BIO-922) is a small molecule PICK1 inhibitor that specificly blocks the PDZ domain-mediated interaction between GluA2 and PICK1 (IC50=69 nM), blocks the effects of Aβ on synaptic transmission and surface receptors. |
|
DC8368 |
BIO-acetoxime
Featured
BIO-Acetoxime is an analog of the GSK3 inhibitor 6-bromoindirubin-3’-oxime, or BIO |
667463-85-6 |
DC20320 |
Bio-AMS
Bio-AMS is a chemical inhibitor of Mycobacterium tuberculosis biotin protein ligase ( MtBPL) with Kd of 0.865 nM. |
1393881-52-1 |
DC23078 |
Biperiden
Featured
Biperiden (KL 373) is a centrally-acting antiparkinsonian agent that functions as a selective central M1 cholinoreceptors blocker.. |
514-65-8 |
DC25079 |
Biperiden hydrochloride
Featured
Biperiden Hcl (NSC 170950, NSC 84989) is a centrally-acting antiparkinsonian agent that functions as a selective central M1 cholinoreceptors blocker.. |
1235-82-1 |
DC5023 |
Birinapant (TL32711)
Featured
Birinapant (TL32711) is a SMAC mimetic antagonist, mostly to cIAP1 with Kd of <1 nM, less potent to XIAP. |
1260251-31-7 |
DC10863 |
Bis(tributylammonium) difluoromethylenediphosphonate
Featured
Bis(tributylammonium) difluoromethylenediphosphonate |
81336-71-2 |
DC10504 |
BISF-3
Featured
BISF CAS 118511-97-0 |
118511-97-0 |
DC20798 |
Bisperoxovanadium
Bisperoxovanadium (bpV(phen) potassium hydrate) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 =38 nM), also inhibits the vascular endothelial PTP, PTP-β (IC50=3 |
171202-16-7 |
DC20212 |
Bisphenol A
Bisphenol A is a starting material for the synthesis of plastics, primarily certain polycarbonates and epoxy resins, as well as some polysulfones and certain niche materials. It exhibits estrogen-mimicking, hormone-like properties. |
80-05-7 |
DC21599 |
Bis-T-23
Bis-T-23 is a small molecule that stimulates actin-dependent dynamin oligomerization and promotes dynamin GTPase activity, increases actin polymerization in injured podocytes. |
171674-76-3 |
DC11307 |
Bitertanol
Bitertanol is a broad-spectrum triazole fungicide that is active against a variety of fungi, including V. inaequalis and V. pirina. |
55179-31-2 |
DC9616 |
BIX 02565
Featured
BIX 02565 is a novel ribosomal S6 kinase 2 (RSK2) inhibitor with an IC50 of 1.1 nM. |
1311367-27-7 |