| DC49911 |
Phenyl sulfamate |
Phenyl sulfamate is a nitrogen source that can be used in the amination of intermolecular. |
|
| DC49912 |
(+)-Coclaurine hydrochloride |
(+)-Coclaurine ((+)-(R)-Coclaurine) hydrochloride, benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine hydrochloride has anti-aging activity. |
|
| DC49913 |
HDP 30.1699 |
HDP 30.1699, the derivative of α-Amanitin，shows considerable cross-links. The cysteine residues of the anti-HER2 THIOMAB antibody are used for conjugation of the cysteine reactive linker–Amanitin compound, HDP 30.1699, with a cleavable linker by maleimide chemistry. |
|
| DC49916 |
Vanin-1-IN-2 |
Vanin-1-IN-2 is a potent vanin-1 inhibitor with an IC50 of 162 nM. Vanin-1 is a cell-surface-associated, glycosylphosphatidyl inositol (GPI)-anchored protein which is expressed at high levels in the kidney, liver, and small intestine. |
|
| DC49917 |
Nur77 modulator 2 |
Nur77 modulator 2, a Nur77 modulator (Kd of 0.35 μM), is a potent and orally active inflammation inhibitor. Nur77 modulator 2 modulates the colocalization of Nur77 at mitochondria. |
|
| DC49919 |
FEN1-IN-SC13
Featured
|
FEN1-IN-SC13 is a potent DNA fragmentation endonuclease 1 (FEN1) inhibitor (CN106692155A, SC13). |
|
| DC49920 |
W36017 |
W3601 is the impurity of Lidocaine. W3601 exhibits nerve blocking activity with the pKa of 7.4. |
|
| DC49921 |
BTC tetrapotassium |
BTC tetrapotassium is a low affinity calcium indicator (Kd approximately 7-26 µM) featuring many desirable properties for cellular calcium imaging, including long excitation wavelengths (400/485 nm), low sensitivity to Mg2+, and accuracy of ratiometric measurement. |
|
| DC49922 |
Dihydrorhodamine 6G |
Dihydrorhodamine 6G (DHR 6G) is the reduced form of Rhodamine 6G, which is used as fluorescent mitochondrial dye. It is nonfluorescent, but it readily enters most of the cells and is oxidized by oxidative species or by cellular redox systems to the fluorescent rhodamine 6G that accumulates in mitochondrial membranes. Dihydrorhodamine 6G is useful for detecting reactive oxygen species (ROS) including superoxide. |
|
| DC49923 |
B10-S |
B10-S is a potent anti-allergic agent. B10-S can inhibit the degranulation of LAD2 induced by substance P. |
|
| DC49924 |
DiAzK |
DiAzK is a bifunctional amino acid. DiAzK can be inserted into almost any protein interface with minimal structural perturbation using genetic code expansion. |
|
| DC49925 |
Allyl (2-aminoethyl)carbamate |
Allyl (2-aminoethyl)carbamate is a cleavable linker. |
|
| DC49926 |
LY3372689 |
LY3372689 is an orally active O-GlcNAcase (OGA) enzyme inhibitor. LY3372689 can be used for tauopathies research, including Alzheimer’s disease. |
|
| DC49927 |
O-GlcNAcase-IN-4 |
O-GlcNAcase-IN-4 is a O-GlcNAcase inhibitor extracted from patent WO2018140299A1 Formulaic Ic. O-GlcNAcase-IN-4 can be used for the research of neurodegenerative diseases and disorders, such as Alzheimer's disease. |
|
| DC49928 |
4-PQBH |
4-PQBH is a potent Nur77 binder (KD=1.17 μM). 4-PQBH extensively induces caspase-independent cytoplasmic vacuolization and paraptosis through Nur77-mediated ER stress and autophagy. 4-PQBH can be used for cancer research. |
|
| DC49929 |
Ethylene glycol diacrylate |
Ethylene glycol diacrylate (Ethylene diacrylate) is a cross-linking homobifunctional reagent. Ethylene glycol diacrylate can be polymerized to form poly(ethylene glycol) diacrylate for drug delivery. |
|
| DC49930 |
(R)-BDP9066 |
(R)-BDP9066 is a potent inhibitor of myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK). (R)-BDP9066 blocks cancer cell invasion. (R)-BDP9066 has the potential for the research of proliferative diseases, such as cancer. |
|
| DC49931 |
NVP-DKY709
Featured
|
NVP-DKY709 is a potent IKZF2 inhibitor for the treatment of cancers. |
|
| DC49932 |
FTT5
Featured
|
FTT5 is a lipid-like compound for efficient delivery of long mRNAs in vivo. |
|
| DC49933 |
GFP150 TFA |
GFP150 TFA is a green fluorescent protein used for labeling proteins. |
|
| DC49934 |
3CPLro-IN-1 |
3CPLro-IN-1 (compound A17) is a potent and orally active inhibitor of SARS-CoV-2 3CLpro with an IC50 of 5.65 μM. 3-Chymotrypsin-like cysteine protease (3CLpro) is an indispensable protein in viral replication and represents an attractive drug target for fighting COVID-19. |
|
| DC49935 |
THR-β agonist 2 |
THR-β agonist 2 is a potent agonist of THR-β. THR-β agonist 2 has the potential for the research of metabolic diseases such as obesity, hyperlipidemia, hypercholesterolemia, diabetes and other conditions such as steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis and other related conditions and diseases (extracted from patent WO2021121210A1, compound 3). |
|
| DC49936 |
Glucobrassicanapin potassium |
Glucobrassicanapin (4-Pentenylglucosinolate) potassium is an aliphatic glucosinolate in vegetable crops of Brassica rapa. |
|
| DC49937 |
BAY-888 |
BAY-888 exhibits IC50 value of 1.5 nM and 5.5 nM towards CSNK1A1 and CSNK1D, respectively. |
|
| DC49938 |
BAY-204 |
BAY-204 is an inhibitor of Casein kinase 1 alpha and delta (CSNK1α and δ) useful for the treatment of proliferative disorders. |
|
| DC49939 |
MIF-IN-4 hydrochloride |
MIF-IN-4 hydrochloride is potent macrophage migration inhibitory factor (MIF) inhibitor (pIC50=5.01-6). MIF is a cytokine originally found to play a role in inhibiting macrophage migration. |
|
| DC49940 |
LC kinetic stabilizer-1 |
LC kinetic stabilizer-1 (compound 21) is a potent and selective amyloidogenic immunoglobulin light chain kinetic stabilizer with EC50s of 140 and 74.1 nM for WIL-FL* and WIL-FL* T46L/F49Y, respectively. WIL-FL is an amyloidogenic FL LC dimer. |
|
| DC49941 |
(R)-CFT7455 |
(R)-CFT7455 is a IKZF1/3 degrader extracted from patent WO2020210630A1. (R)-CFT7455 can be used for the research of defective proteasomal degradation. |
|
| DC49942 |
BDP-4 |
BDP-4 is an amino acid-modified near-infrared Aza-BODIPY photosensitizer, acts as an immune initiator for potent photodynamic therapy in melanoma. |
|
| DC49943 |
Spermine Prodrug-1 |
Spermine Prodrug-1 (Compound 1) is a redox-sensitive spermine prodrug for the potential treatment of snyder robinson syndrome. Spermine Prodrug-1 inhibits wild-type (CMS-24949) and spermine synthase gene (SMS) mutant (CMS-26559, and CMS-6233) fibroblast cells with IC50s of 326.7, 198.5, and 244.1 μM, respectively. |
|
