| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11650 | Ro5-4864 Featured | A potent, selective ligand for the mitochondrial translocator protein 18kDa (TSPO/PBR). |
|
| DC22858 | LIMK-IN-14 | A potent, selective LIMK inhibitor with IC50 of 0.9 nM and 0.5 nM and 1.2 nM for LIMK1 and LIMK2, respectively. |
|
| DC22859 | LIMK-IN-22j | A potent, selective LIMK inhibitor with IC50 of 3.2 nM and 1.2 nM for LIMK1 and LIMK2, respectively. |
|
| DC24026 | LPA2-IN-1 | A potent, selective LPA2 (EDG4) antagonist with IC50 of 17 nM. |
|
| DC22364 | DG051 | A potent, selective LTA4H (Leukotriene A4 hydrolase) inhibitor (IC50/Kd=47/25 nM) of leukotriene B4 biosynthesis. |
|
| DC20722 | AZD-1979 | A potent, selective melanin concentrating hormone receptor 1 (MCH-R1) antagonist with binding Ki of 12.2 nM. |
|
| DC26072 | BMS 819881 | A potent, selective melanin concentrating hormone receptor 1 (MCHR1) inhibitor with Ki of 10.4 nM. |
|
| DC22710 | LY3020371 hydrochloride | A potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, respectively. |
|
| DC22921 | AMN 082 | A potent, selective mGluR7 allosteric agonist that inhibits forskolin-stimulated cAMP accumulation in mGluR7b CHO cells with EC50 of 64±32 nM. |
|
| DC21573 | Ro 5212773 Featured | EPPTB is a selective antagonist of the trace amine-associated receptor 1 (TAAR1). |
|
| DC24163 | XEN-907 | A potent, selective NaV1.7 blocker with IC50 of 3 nM. |
|
| DC23603 | Traxoprodil mesylate Featured | A potent, selective N-methyl-D-aspartate (NMDA) antagonist with selectivity for the NR2B subunit. |
|
| DC20771 | Faldaprevir | A potent, selective noncovalent competitive inhibitor of HCV NS3/4A protease with Ki of 2.6 and 2.0 nM for GT1a and 1b NS3-NS4A protease, respectively. |
|
| DC22726 | SB 290157 | A potent, selective nonpeptide antagonist of anaphylatoxin C3a receptor (C3aR) with IC50 of 200 nM. |
|
| DC22672 | SB-612111 hydrochloride | A potent, selective opiate receptor-like orphan receptor (ORL-1, NOP) antagonist with Ki of 0.33 nM. |
|
| DC22947 | RN-9893 hydrochloride | A potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively. |
|
| DC22951 | RN-9893 | A potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively. |
|
| DC24064 | SB-408124 hydrochloride Featured | A potent, selective OX1 receptor antagonist with Ki of 57 nM (whole cell assay), and 27 nM (cell membrane-based SPA assay). |
|
| DC23213 | SCIO-469 | A potent, selective p38α MAPK inhibitor with IC50 of 9 nM. |
|
| DC22577 | Revizinone | A potent, selective PDE3 inhibitor with IC50 of 36 nM, displays >20,000-fold selectivity over PDE1.. |
|
| DC22963 | Org-9935 | A potent, selective PDE3 inhibitor with IC50 of 50 nM. |
|
| DC22942 | BeKm-1 | A potent, selective peptide inhibitor of hERG channel with IC50 of 3.3 nM for hERG1 channels. |
|
| DC22767 | UK-500001 | A potent, selective phosphodiesterase 4 (PDE4) inhibitor with IC50 of 26.1, 22.8, 21 and 0.28 nM for PDE4A4, PDE4B2, PDE4C2 and PDE4D3, respectively.. |
|
| DC22535 | CGP-25454A | A potent, selective presynaptic dopamine autoreceptor antagonist. |
|
| DC21587 | RR 601 | A potent, selective protein tyrosine phosphatase DUSP5, PTP1B and SHP-2 inhibitor with IC50 of 36 uM, 2.1 and 1.1 uM respectively, 8-fold selectivity for PTP1B versus DUSP5. |
|
| DC26105 | AGN-195183 | A potent, selective RARα agonist. |
|
| DC22996 | LE-540 | A potent, selective RARβ antagonist that inhibits RA-induced transcriptional activation of RARβ, but not RARα, RARγ or RXRα on a variety of RA response elements. |
|
| DC22547 | RIPK2-IN-2 | A potent, selective receptor interacting protein-2 (RIP2) kinase inhibitor.. |
|
| DC22701 | SEW2871 | A potent, selective S1P1 receptor full agonist with EC50 of 13.8 nM, with no activites at the S1P2-5 receptors. |
|
| DC22702 | PD144418 | A potent, selective sigma 1 ligand with Ki of 0.08 nM, >3000-fold selectivity over sigma 2 (Ki=1377 nM). |
|
