DCC4179 |
Pkcθ-in-41 |
Novel selective inhibitor of protein kinase Cθ (PKCθ) |
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DCC4180 |
Pkm2-in-8 |
Novel highly potent and selective PKM2 inhibitor, blocking PKM2 mitochondrial translocation under nutritional stress and inhibits tumor growth in vivo |
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DCC4181 |
Pks21272 |
Novel potent and specific β5i inhibitor |
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DCC4182 |
Pkumdl-ltq-301 |
Potent inhibitor of HipA toxin, inhibiting E. coli persistence |
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DCC4183 |
Pladienolide B |
mRNA splicing inhibitor |
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DCC4184 |
Plafibride |
Antilipidemic and antiplatelet agent |
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DCC4185 |
Plap Inhibitor 16 |
Novel Potent and Specific Inhibitor of Placental Alkaline Phosphatase (PLAP; IC 50 = 32 nM), Targeting Tumor of the Female Reproductive Tract |
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DCC4186 |
Plasiatine |
Novel Potent Activator of the Nonreceptor Protein Tyrosine Phosphatase Shp2 |
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DCC4187 |
Plaunotol |
Gastroprotective agent, increasing the prostaglandin production in the gastric mucosa and accelerates ulcer healing |
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DCC4188 |
Plazomicin |
Broad spectrum aminoglycoside antibiotic typically used for moderate-to-severe urinary tract infections or pyelonephritis |
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DCC4189 |
Plc Inhibitor 3017 |
Novel inhibitor of phospholipase C (PLC) isozyme |
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DCC4190 |
pl-dhn |
Novel enhancer of Reactive Oxygen Species (ROS), depleting glutathione levels in analogy to piperlongumine but with reduced cell death |
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DCC4191 |
Plectranthoic Acid |
Novel activator of AMPK, inducing apoptotic death in prostate cancer cells |
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DCC4192 |
Plhspt |
Plk1 PBD-specific phosphopeptide inhibitor, effectively inhibiting mitotic progression and cell proliferation |
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DCC4193 |
Plk1 Pbd-in-143 |
Novel Inhibitor of the Polo-Box Domain of Polo-like Kinase 1 (Plk1 PBD) |
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DCC4194 |
Plk1-in-7k |
Novel polo-like kinase 1 (PLK1) inhibitor |
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DCC4195 |
Plx647(ome) |
Slightly less potent inhibitor of FMS than PLX647 but has better aqueous solubility |
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DCC4196 |
Pm00104 |
Potent anticancer tetrahydroisoquinoline alkaloid, being able to form a covalent bond with the amino group of a guanine in selected triplets of DNA duplexes and eventually give rise to double-strand breaks |
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DCC4197 |
Pmed-1 |
Novel inhibitor of β-catenin signaling, significantly reduced β-catenin activity in hepatoblastoma and several HCC cells |
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DCC4198 |
Pmmb-317 |
Novel potent irriversible dual inhibitor of tubulin and epidermal growth factor receptor (EGFR), inducing the apoptosis of A549 cells in a dose- and time-dependent manner, along with decrease in mitochondrial membrane potential (MMP), production of ROS an |
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DCC4199 |
Pmpmease-in L-23 |
Novel inhibitor of prenylated methylated protein methyl esterase (PMPMEase), a key enzyme in the reversible methylation/demethylation step in the protein prenylation pathway |
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DCC4200 |
Pmpmease-in L-28 |
Novel inhibitor of prenylated methylated protein methyl esterase (PMPMEase), a key enzyme in the reversible methylation/demethylation step in the protein prenylation pathway |
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DCC4201 |
P-mppf Dihydrochloride |
Selective 5-HT1A serotonin receptor antagonist |
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DCC4202 |
P-nitro-pifithrin-α |
Cell-permeable analog of pifithrin-α, potently blocking p53-mediated expression of p21/WAF1 and apoptosis |
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DCC4203 |
Pnr-4-20 |
Novel G Protein-Biased Cannabinoid 1 (CB1) Receptor Agonist |
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DCC4204 |
Pnu-292137 |
Potent inhibitor of CDK2/cyclin A |
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DCC4205 |
Pnu-69176e |
Allosteric modulator of 5-HT(2C)R with no intrinsic agonist activity |
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DCC4206 |
Pnz-tmp |
The first small-molecule approach capable of detecting and controlling engineered cell-cell outputs |
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DCC4207 |
Podoverine A |
Novel microtubule destabilizing natural product from the Podophyllum species |
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DCC4208 |
Pol I Inhibitor T5 |
Novel RNA polymerase I inhibitor, targeting ribosomal DNA G-quadruplexes, potently and selectively inhibiting cell growth by high-affinity binding to G4s in ribosomal DNA, impairing RNA polymerase I (Pol I) elongation, inducing a rapid inhibition of Pol I |
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