DCC5021 |
Talaroconvolutin A |
Natural ferroptosis inducer, killing colorectal cancer cells in vitro and in vivo |
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DCC5022 |
Talarozole |
CYP26 inhibitor, potentiating the effects of all-trans retinoic acid on cultured human epidermal keratinocytes |
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DCC5023 |
Talaumidin |
Natural neurotrophic agent, promoting neurite outgrowth from neurons through PI3K/Akt pathway |
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DCC5024 |
Talirine |
Novel Antibody-Drug Conjugate PBD Dimer Payload |
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DCC5025 |
Taltirelin |
Superagonist at the human thyrotropin-releasing hormone receptor, reversing opioid-induced respiratory depression in isoflurane anesthetized rats |
|
DCC5026 |
Tamra-edatp |
Novel Fluorescent dATP for DNA Synthesis In Vivo, exhibited high brightness, low toxicity, and rapid incorporation and depletion kinetics in both a vertebrate (zebrafish) and a nematode (Caenorhabditis elegans) |
|
DCC5027 |
Tan-67 |
Potent and selective non-peptide δ1 opioid receptor agonist |
|
DCC5028 |
Tanshinol Borneol Ester |
Novel angiogenesis stimulator, promoting multiple key steps of angiogenesis parially via Akt and MAPK signalling pathways, showing anti-ischemic and anti-atherosclerosis activities, also acting as a putative PPARγ agonist |
|
DCC5029 |
Tap1a-opt1 |
Novel potent Na V -targeting peptide, exhibiting significant increased potency for Na V 1.1, Na V 1.2, Na V 1.3, Na V 1.6 and Na V 1.7 involved in several neurological disorders including acute and chronic pain, motor neuron disease and epilepsy |
|
DCC5030 |
Tap1a-opt2 |
Novel potent Na V -targeting peptide, exhibiting significant increased potency for Na V 1.1, Na V 1.2, Na V 1.3, Na V 1.6 and Na V 1.7 involved in several neurological disorders including acute and chronic pain, motor neuron disease and epilepsy |
|
DCC5031 |
Tapi-2 Acetate |
ADAM-17 (TACE) and MMP inhibitor, sensitizing cancer stem cells to the lethal effects of 5-FU and blocking shedding of TNF-α from cell membranes |
|
DCC5032 |
Tariquidar Dimesylate |
Potent P-glycoprotein (P-gp) inhibitor |
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DCC5033 |
Tas-303 Hydrochloride |
Novel selective norepinephrine reuptake inhibitor, displaying significant norepinephrine transporter (NET) inhibitory activity toward the serotonin or dopamine transporters |
|
DCC5034 |
tasidotin Hydrochloride |
Tubulin-binding dolastatin-15 analog, demostrating a wide spectrum of In Vivo antitumor activity |
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DCC5035 |
Tasp0233278 |
Potent and orally active V 1B receptor antagonist with antidepressant and anxiolytic activities in rodents |
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DCC5036 |
Tasp0277308 |
Potent and selective sphingosine 1-phosphate 1 (S1P1) receptor antagonist (IC50 = 7.8 nM) |
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DCC5037 |
Tasp0412098 |
Novel potent, selective, and orally active CRTH2 antagonist |
|
DCC5038 |
Tat Peptide (47-57) |
Trans-activator of transcription (TAT) peptide, increasing Hepta-histidine (7H) permeability into cells for treatment of iPS cell-derived neurons carrying Tau or APP mutations suppressed Tau phosphorylation |
|
DCC5039 |
Tat-gap19 |
Novel brain penetrant Cx43 hemichannel blocker |
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DCC5040 |
Tavarua Deoxyriboside A |
Potential neuroprotective agent, showing effects on cellular models of oxidative stress and neuroinflammation |
|
DCC5041 |
Tazanolast |
Selective mast-cell-stabilizing agent, inhibiting ozone-induced airway hyperresponsiveness |
|
DCC5042 |
Tb-2-081 |
Novel antagonist of IL-6 signaling |
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DCC5043 |
Tbbl-0000316 |
Novel antibiotic against Mycobacterium tuberculosis (Mtb), potently killing replicating, virulent Mtb H37Rv in a clavulanate-dependent manner |
|
DCC5044 |
Tbdps-chc |
Novel potent MCT1 inhibitor, exhibiting good single agent anticancer efficacy properties |
|
DCC5045 |
Tbe-31 |
Highly potent activator of Nrf2; Potent phase 2 cytoprotective pathway inducer and liver carcinogenesis blocker |
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DCC5046 |
Tbk1 Inhibitor-1 |
Novel TBK1/IKKε inhibitor |
|
DCC5047 |
Tbz-07 |
Novel anti-angiogenesis and vascular disrupting agent, exhibiting moderate inhibitory cell proliferation activity |
|
DCC5048 |
Tbz-19 |
Novel anti-angiogenesis and vascular disrupting agent, exhibiting moderate inhibitory cell proliferation activity |
|
DCC5049 |
Tc299423 |
Novel agonist for nicotinic acetylcholine receptors (nAChRs), modestly selectively targeting α6β2 subtype |
|
DCC5050 |
Tc-ac28 |
Novel potent and selective ligand of Brd2(2) |
|