DCC5051 |
Tc-aqp1-1 |
Aquaporin 1 (AQP1) channel blocker |
|
DCC5052 |
tc-c-14g |
Potent CB1 receptor inverse agonist |
|
DCC5053 |
Tc-e 5006 |
Novel orally bioavailableγ-secretase modulator, reducing Aβ42 levels |
|
DCC5054 |
FPR Agonist 43
Featured
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FPR Agonist 43 (compound 43) is a dual formyl peptide receptor 1 (FPR1) and formyl peptide receptor 2 (FPR2)/ALX agonist. |
|
DCC5055 |
Tc-g1004 |
Potent and selective antagonist of adenosine A2A receptors |
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DCC5056 |
Tch-013 |
Non-competitive modulator of the proteasome inducing apoptosis a panel of myeloma and leukemia cell lines |
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DCC5057 |
Tc-i 2000
Featured
|
Novel TRPM8 channel blocker |
|
DCC5058 |
Tc-i 2014 |
Potent TRPM8 antagonist, exhibiting antiallodynic properties in pain models |
|
DCC5059 |
tcmdc-125802 |
Antimalarial; Novel inhibitor of HepG2 |
|
DCC5060 |
Tcmdc-135051 Tfa Salt |
Novel Inhibitor of the malaria parasite protein kinase CLK3, inhibiting the development of liver-stage parasites, killing asexual blood-stage parasites at the trophozoite and schizont stages of the erythrocytic cycle, blocking the development of sexual ga |
|
DCC5061 |
Tcn-237 Dihydrochloride |
Highly potent NR2B-selective NMDA receptor antagonist |
|
DCC5062 |
Tc-ot-39 |
Nonpeptide partial agonist of oxytocin (OT) and vasopressin V2 receptors |
|
DCC5063 |
Tc-s 7005 |
Potent and selective polo-like kinase 2 (PLK2) inhibitor |
|
DCC5064 |
Tcs2312 |
Novel potent and selective CHK1 kinase inhibitor |
|
DCC5065 |
Tcs2314
Featured
|
Novel Integrin very late antigen-4 (VLA-4; α4β1) antagonist, blocking the activation of inflammatory cells. |
|
DCC5066 |
Tcs-3035 |
Novel GPR35 agonist |
|
DCC5067 |
Tcs-401 |
Insulin receptor sensitizing agent; Selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B) |
|
DCC5068 |
Tc-t 6000 |
Potent equilibrative nucleoside transporter 4 (ENT4) inhibitor |
|
DCC5069 |
T-cupm |
Sorafenib analogue, retaining cytotoxicity similar to sorafenib in various human cancer cell lines and strongly inhibiting growth in the NCI-60 cell line panel |
|
DCC5070 |
Td-004 |
Novel degrader of the anaplastic lymphoma kinase (ALK) fusion protein, effectively inducing ALK degradation and inhibiting the growth of ALK fusion positive cell lines, SU-DHL-1 and H3122, significantly reducing the tumor growth in H3122 xenograft model |
|
DCC5071 |
Td-106 |
Novel IKZF1/3 degrader, inhibiting the proliferation of multiple myeloma cells in vitro as well as in vivo |
|
DCC5072 |
Td-1211 |
Novel selective opioid receptor antagonist at all three receptor types |
|
DCC5073 |
Td-428 |
Novel potent BET protein degrader, inhibiting cell proliferation due to suppressed C-MYC transcription |
|
DCC5074 |
Td-5471 Hydrochloride |
Novel long-acting β 2 -adrenoceptor agonist |
|
DCC5075 |
Tdcipp |
Hepatotoxicity inducer, significantly up-regulating the expression of genes involved in endoplasmic reticulum stress and Toll-like receptor (TLR) pathway |
|
DCC5076 |
Tdmq20 |
Novel Specific Copper Chelator, Reducing Memory Impairments in Alzheimer's Disease Mouse Models |
|
DCC5077 |
Tdp1-in-9a |
Novel potent inhibitor of tyrosyl-DNA phosphodiesterase 1 (Tdp1) |
|
DCC5078 |
Tdp222669 |
Novel inhibitor of the p53-Hdm2 protein-protein interaction, dose-dependently stabilized P53 and increased P21 and MDM2 expression in JAR choriocarcinoma cells, inducing the p53 regulated gene (PIG-3) and caspase activity |
|
DCC5079 |
Tdr32570 |
Novel antimalarial agent |
|
DCC5080 |
Tecovirimat Hydrate
Featured
|
Novel inhibitor of viral p37, blocking the ability of virus particles to be released from infected cells, being used for the treatment of smallpox, monkeypox, orthopoxvirus, and orthopoxviral Disease. |
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