| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DCC5260 | Ttk Protac 8j | First-in-class potent threonine tyrosine kinase (TTK) PROTAC, demonstrating strong TTK degradation in COLO-205 human colorectal cancer cells with DC 50 values of 3.1 nM |
|
| DCC5261 | Ttr Stabilizer L6 | Novel transthyretin (TTR) stabilizer, binding to the T4 binding pocket of TTR and preventing the dissociation of TTR to monomer |
|
| DCC5262 | Ttt-3002 | FLT3 Kinase Inhibitor, Overcoming Both Activating and Drug Resistance Mutations in FLT3 in Acute Myeloid Leukemia |
|
| DCC5263 | Tu-514 | LpxC substrate-analog inhibitor |
|
| DCC5264 | Tubulin-in-3n | Novel inhibitor of tubulin polymerization and caused HepG2 cells arrest in G2/M phase |
|
| DCC5265 | Tubulin-in-iia | Novel potent tubulin polymerization inhibitor, forming stable interactions in the colchicine-binding site of tubulin, showing significant antiproliferative activities on a panel of tumor cell lines |
|
| DCC5266 | Tug-1907 | Novel allosteric modulator of free fatty acid receptor 3 (FFA3, previously GPR41) |
|
| DCC5267 | Tug-2015 | Novel allosteric modulator of free fatty acid receptor 3 (FFA3, previously GPR41) |
|
| DCC5268 | Tulobuterol Hydrochloride | Long-acting beta2-adrenergic receptor agonist |
|
| DCC5269 | tumor Metastasis Blocker 5k | Novel Inhibitor of Metastatic Cancer Cell Migration and Invasion |
|
| DCC5270 | Tunicamycin | Antibiotic, inhibiting the first step in the N-linked glycosylation in eukaryotes and inducing ER stress to activate the unfolded protein response (UPR) |
|
| DCC5271 | Turneroic Acid | Inhibitor of bacterial biofilm formation in Staphylococcus epidermidis |
|
| DCC5272 | Tutuilamide A | Natural potent porcine pancreatic elastase (PPE) inhibitor |
|
| DCC5273 | Txa1 Hydrochloride | Novel anticancer agent, affecting steroid biosynthesis, increasing RagD expression, and causing abnormal cellular cholesterol localization |
|
| DCC5274 | Txa-709 | Novel disruptor of the bacterial protein, FtsZ |
|
| DCC5275 | Ty-51469 | Chymase inhibitor, preventing the development and progression of non-alcoholic steatohepatitis, improving vascular dysfunction and survival in stroke-prone spontaneously hypertensive rats |
|
| DCC5276 | Tyk2 Jh2-in-48 | Novel highly potent and selective TYK2 JH2 inhibitor, providing robust inhibition in a mouse IL-12-induced IFNγ pharmacodynamic model as well as efficacy in an IL-23 and IL-12-dependent mouse colitis model |
|
| DCC5277 | Bll5 Maleate | First-in-class selective PRMT5 inhibitor, blocking EBV-driven B lymphocyte transformation and survival while leaving normal B cells unaffected |
|
| DCC5278 | Tyr(po(nme2)2 | Stable analog of phosphotyrosine (pTyr) |
|
| DCC5279 | Tyrosinase Inhibitor Thio-2 | Novel competitive inhibitor of tyrosinase enzyme |
|
| DCC5280 | U-101958 Maleate [224170-09-6] | Potent and selective dopamine D4 receptor antagonist |
|
| DCC5281 | Ua62784 | Novel potent inhibitor of microtubule polymerization, binding directly to tubulin α/β heterodimers via the colchicine-binding site, perturbing mitotic spindles, delaying cells in mitosis and promotes apoptosis |
|
| DCC5282 | Uawj172 | Novel potent and broad-spectrum antiviral agent against multiple strains of EV-D68, EV-A71, and CVB3, targeting the viral protein 2C |
|
| DCC5283 | Ubp512 | Selective modulator of NMDA_receptor>NMDA receptors, potentiates responses at GluN1/GluN2A |
|
| DCC5284 | Ubp618 | Novel pan-inhibitor of GluN1/GluN2 receptors |
|
| DCC5285 | Ubp646 | Novel pan potentiator of GluN1/GluN2 receptors |
|
| DCC5286 | Ubp684 | Novel NMDAR positive allosteric modulator (PAM), robustly potentiating responses at all GluN1/GluN2 subtypes and at neuronal NMDARs |
|
| DCC5287 | Ubtr008295a | Novel Antagonist of the USP5 Zinc Finger Ubiquitin-Binding Domain (USP5 ZnF-UBD) |
|
| DCC5288 | Ucb-11056 | Modulator of cyclic AMP generation, amplifing induced cyclic AMP formation in rat brain tissue; Nootropic |
|
| DCC5289 | ucb30889 | Potent ligand of synaptic vesicle protein 2A (SV2A) |
|
