| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC73918 | BD442618 | BD442618 (BD 442618) is a potent small-molecule GPR52 agonist. |
|
| DC73919 | BD50265 | BD50265 (BD 50265) is a potent small-molecule GPR52 agonist. |
|
| DC73920 | BI-0955 | BI-0955 is an inactive HSD17B13 control compound for BI-3231. |
|
| DC73921 | BI-9466 | BI-9466 (BI 9466) is the negative control of NSD3-PWWP1 domain chemical probe BI-9321. |
|
| DC73922 | BiTud | BiTud is a bivalent inhibitor against TDRD3 with binding Kd of 6 uM for tandem Tudor chimera, blocks the recruitment of TDRD3 by the two methylated arginines of G3BP1, suppress the phase separation of methylated G3BP1, TDRD3, and RNAs, and in turn inhibit |
|
| DC73923 | BK697 | BK697 is a small molecule targeting FIRΔexon2, potentially interacts with FIRΔexon2, significantly suppresses the FIRΔexon2 expression and inhibits tumor cell growth and several rRNA expressions. |
|
| DC73924 | BNZ-1 | BNZ-1 (BNZ132-1-40) is a pegylated peptide, BNZ132-1 conjugated with methoxy-PEG40 maleimide molecule via a specific linker (CGSGG), specifically binds the γc receptor to selectively block IL-2, IL-15 and IL-9 signaling. |
|
| DC73925 | BNZ132-1 | BNZ132-1 (QITISILSQINRVFHEKFI) is a specific peptide inhibitor for the IL-2/IL-15 subfamily, directly binds to the γc molecule (CD132). |
|
| DC73926 | BR102910 | BR102910 (BR 102910) is a novel potent, selective, oral fibroblast activation protein (FAP) inhibitor with IC50 of 1 nM. |
|
| DC73927 | BRD4780 | BRD4780 is a small molecule that releases MUC1-fs from TMED9-enriched compartments and promotes its anterograde trafficking to the lysosome, directly binds to TMED9. |
|
| DC73928 | BRD8518 | BRD8518 is a specific small molecule TRIB1 inducer, modulates expression of the key genes involved in VLDL production and in LDL clearance in HepG2 cells. |
|
| DC73929 | BRM011 | BRM011 (dual BRM and BRG1 inhibitor 11) is a potent, selective, allosteric dual BRM and BRG1 inhibitor with IC50 of <5 nM for both. |
|
| DC73930 | Butaselen | Butaselen is a small molecule inhibitor of thioredoxin reductase (TrxR)/thioredoxin (Trx) with anti-tumor activity, inhibits the growth of various human cancer cell lines. |
|
| DC73931 | C105SR | C105SR is small-molecule cyclophilin inhibitor with IC50 of 5 nM for inhibition of CypD PPIase activity and 9 nM for mitochondrial swelling. |
|
| DC73932 | C10M | C10M is a small molecule inhibitor of C-reactive protein (CRP), inhibits the binding of pCRP to the physiological ligand phosphocholine (PC) with IC50 of 1.5 mM in ELISA assays. |
|
| DC73933 | C902 Featured | C902 is a small-molecule inhibitor targeting LIN28-let-7 interaction, shows dose-dependent inhibition in an EMSA validation assay with IC50 of 5 uM. |
|
| DC73934 | Calmirasone1 | Calmirasone1 (Calmirasone 1) is a novel and potent covalent calmodulin (CaM) inhibitor with Kd of 0.87 uM. |
|
| DC73935 | CARD8 activator CQ31 | CARD8 activator CQ31 is a small molecule that selectively activates CARD8. |
|
| DC73936 | CASK chemical probe 18 | CASK chemical probe 18 is a highly potent and selective CASK inhibitor with IC50 of 22 nM. |
|
| DC73937 | CB253 | CB253 is a small molecule that selectively binds the hairpin form of r(G4C2)exp, inhibiting mechanisms that drive c9ALS/FTD pathobiology. |
|
| DC73938 | CBK034026C | CBK034026C is a small molecule targeting metabolic vulnerabilities caused by N-acetyltransferase 2 (NAT2) activity, exhibits specific toxicity towards colorectal cancer (CRC) cells with high NAT2 activity. |
|
| DC73939 | CBLC000 | CBLC000 (CBL0100) is a small molecule histone chaperone FACT inhibitor, activates p53 and inhibits NF-κB with EC50 of 0.06 and 0.03 uM in cell-based p53 and NF-κB reporter assays, respecitvely. |
|
| DC73940 | CC-410 | CC-410 (CC410) is a potent, specific inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 of 1.6 uM (human NNMT). |
|
| DC73941 | CHD1Li 11 | CHD1Li 11 (CHD1L inhibitor 11) is a small molecule inhibitor of chromodomain helicase DNA-binding protein 1 like (CHD1L) with IC50 of 4.57 uM. |
|
| DC73942 | CIB-3b | CIB-3b is a small molecule inhibitor disrupting the TRBP-Dicer interaction, suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells. |
|
| DC73943 | Cimlanod | Cimlanod is a second-generation nitroxyl (HNO) donor.. |
|
| DC73944 | CK147 | CK147 (CK-147) is a potent CD4 down-modulator with IC50 of 63 nM, inhibits Sec61-dependent cotranslational translocation of huCD4 in vitro. |
|
| DC73945 | CKi-4 | Creatine kinase inhibitor CKi-4 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.3 uM, depletes creatine phosphagen energetics in cells. |
|
| DC73946 | CKi-6 | CKi-6 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.6 uM, depletes creatine phosphagen energetics in cells. |
|
| DC73947 | Cl-NIO | Cl-NIO is a potent, selective inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) with Ki of 1.3 uM, > 500-fold selectivity against arginase and endothelial nitric oxide synthase. |
|
