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Cat. No. Product Name Field of Application Chemical Structure
DC34894 Amino-PEG4-t-butyl ester
Amino-PEG4-t-butyl ester is a PEG derivative containing an amino group with a t-butyl protected carboxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34750 DST Crosslinker
DST Crosslinker, or Disuccinimidyl tartrate, is a homobifunctional, cleavable crosslinking reagent (cleavable by oxidizing reagents). DST crosslinker is an excellent choice for applications in which crosslink cleavability is desired without disturbing protein disulfide bonds with reducing reagents.
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DC34733 MBS Crosslinker
MBS crosslinker (m-Maleimidobenzoyl-N-hydroxysuccinimide ester) is a non-cleavable, water insoluble, heterobifunctional protein crosslinking reagent that is commonly used to crosslink haptens to carrier proteins and enzymes to antibody. The MBS crosslinking reagent's NHS ester and maleimide reactive groups react with amino and sulfhydryl moites, respectively. Sulfo-MBS crosslinker is the water soluble analog of MBS protein crosslinker and is a convenient choice if you do not wish to use organic solvents to solubilize MBS protein crosslinking reagent. The MBS protein crosslinker extended spacer arm analog is SMPB crosslinker SATA Protein Modifier can be used to add sulfhydryl groups (thiols, -SH) to proteins or peptides prior to MBS crosslinking.
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DC34730 ANB-NOS Crosslinker
ANB-NOS Crosslinker, also known as N-5-Azido-2-nitrobenzoyloxysuccinimide, is a heterobifunctional protein crosslinker with a spacer arm length of 7.7 angstroms. The ANB-NOS crosslinking reagent contains an NHS ester that reacts with primary amines and a nitrophenylazide group that is photoreactive at 320-350 nm toward amino groups. ANB-NOS Crosslinker is useful for making ADCs (antibody drug conjugates).
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DC34714 Mericycline
Tetracycline, sold under the brand name Sumycin among others, is an antibiotic used to treat a number of infections. This includes acne, cholera, brucellosis, plague, malaria, and syphilis. It possesses some level of bacteriostatic activity against almost all medically relevant aerobic and anaerobic bacterial genera, both Gram-positive and Gram-negative.
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DC34713 Ovisot
Acetylcholine chloride is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
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DC34703 Acetylcysteine
Acetylcysteine has been used to control irritability and aggressive behaviors in patients with autism and other neuropsychiatric disorders. Acetylcysteine has also been used in the treatment of patients with chronic bronchitis and chronic obstructive pulmonary disease (COPD).
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DC34654 Mephenesin
Mephenesin is a centrally acting muscle relaxant with a short duration of action. It can be used as an antidote in strychnine poisoning.
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DC34569 Carboprost tromethamine
Carboprost tromethamine is a Prostaglandin F2α analog.
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DC34468 BLI-489 Hydrate
BLI-489 Hydrate is a novel beta-lactamase inhibitor.
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DC34462 PF-5274857 HCl
PF-5274857 HCl is a potent and selective smoothened (Smo) receptor antagonist.
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DC34457 Nalmefene Hydrochloride
Nalmefene HCl is an antagonist of the opioid receptors.
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DC34432 Brilliant Blue G
Brilliant Blue G is a P2X7 purinergic receptor antagonist.
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DC34383 IDO1-IN-1
IDO1-IN-1 is an inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1).
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DC34322 NBI-35965 Mesylate
NBI-35965 Mesylate is a potent and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist.
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DC34320 Piperlonguminine
Piperlonguminine is an inhibitor of Akt/mTOR signalling. It acts by promoting autophagy and mediating cancer cell death.
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DC34309 CJB-090 2HCl
CJB-090 2HCl is a dopamine D3 receptor partial agonist.
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DC34295 Wee1 Inhibitor I
Wee1 Inhibitor I is an ATP-binding site-targeting inhibitor of Wee1.
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DC34281 6-OHDA HBr
6-OHDA HBr is a neurotoxin. It acts by destroying catecholaminergic terminals.
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DC34266 Flu-IA
Flu-IA is a fluorescent probe that covalently labels DNA fragments.
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DC34260 Methylarbutin
Methylarbutin is an ice recrystallization inhibitor (IRI).
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DC34213 Amethopterin
Amethopterin is a chemotherapy agent and immune system suppressant. It can treat cancer of the blood, bone, lung, breast, head, and neck. It can also treat rheumatoid arthritis and psoriasis.
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DC34199 CBBR
CBBR is an inhibitor of wild type and mutant alpha-synuclein aggregation and a modulator of neurotoxicity. It is also used as a protein staining dye.
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DC34178 CBIO
CBIO is a potent, cell-permeable, D-amino acid oxidase (DAO) reversible inhibitor. In rat models, CBIO prevents formalin-induced tonic pain but not acute nociception.
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DC34166 Quinine sulfate dihydrate
Quinine sulfate dihydrate is an antimalarial agent. It works by reducing oxygen intake and carbohydrate metabolism, disrupting DNA replication and transcription via DNA intercalation, and reducing excitability of muscle fibers via alteration of calcium distribution. It is also an inhibitor of P-glycoprotein.
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DC34139 Dihydroergotamine Mesylate
Dihydroergotamine Mesylate, also known as DHE or Migranal, is an ergot alkaloid used to treat migraines. It has similar actions to the triptans, acting as an agonist to the serotonin receptors and causing vasoconstriction of the intracranial blood vessels, but also interacts centrally with dopamine and adrenergic receptors.
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DC34135 Amoxicillin Trihydrate
Amoxicillin Trihydrate is a broad-spectrum antibiotic. It binds to and inactivates penicillin-binding protein (PBP) 1A located on the inner membrane of the bacterial cell wall. Inactivated PBP interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity.
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DC34068 NPD9948
NPD9948 is a competitive MTH1 inhibitor.
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DC34045 BIR2
BIR2 is a balloon inducing reagent. BIR2 triggers a spontaneous self-organizing program that leads to the formation of a 3-D balloon-shaped structure during hESC differentiation.
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DC34038 Resorufin
Resorufin, also known as OUL47 or NSC12097, is an ARTD10 inhibitor. Resorufin is widely used as an indicator of cell viability in assays.
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