| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC20527 | Ractopamine Featured | A small molecule TAAR1 agonist and β adrenoreceptor agonist that stimulates β1 and β2 adrenergic receptors. |
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| DC21557 | RB-011 | A small molecule that disrupt 14-3-3 dimers at low micromolar concentrations and induce rapid down-regulation of Raf-MAPK and PI3K-Akt signaling in Jurkat cells. |
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| DC11926 | NDMC101 Featured | A small molecule that inhibits NFATc1 and NF-κB activity, inhibits RANKL-induced osteoclastogenesis in vivo. |
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| DC25050 | LCL204 | A small molecule that inhibits N-myristoyltransferase (NMT1) with IC50 of 8.7 uM, 10-fold enhanced inhibitory potency than LCL4. |
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| DC21123 | NSC624548 | A small molecule that inhibits the activities of E. coli DNA polymerase I and calf thymus DNA polymerase alpha.. |
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| DC21418 | NSC 243928 Featured | NSC243928(NSC-243928 ) is a small molecule that potently inhibit ovarian cancer stem-like cells (CSC) growth with GI50 of 0.83 uM, which os consistent with cell death/apoptosis.. |
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| DC22777 | FPH 2(BRD9424) Featured | A small molecule that promotes differentiation of iPS-derived hepatocytes. |
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| DC20356 | DFPM | A small molecule that rapidly downregulates abscisic acid (ABA)-dependent gene expression (IC50=3 and 1.5 uM for RD29B and RAB18 promoters), also inhibits ABA-induced stomatal closure. |
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| DC25025 | Compound A5 | A small molecule that specifically inhibits the clathrin adaptor complex AP-1-dependent traffic, does not significantly affect other pathways through the trans-Golgi network (TGN). |
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| DC22839 | TCA-1 | A small molecule with activity against drug-resistant and persistent tuberculosis. |
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| DC20387 | Galiellalactone | A small molecule, direct STAT3 inhibitor that inhibits the IL-6-induced SEAP expression with IC50 of 200-500 nM, blocks the binding of the activated STAT3 dimers to DNA. |
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| DC22841 | NBD-11021 | A small molecule, full antagonist of CD4 that blocks gp120-CD4 interaction. |
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| DC11498 | FOXO1-IN-8 | A small molecule, selective FOXO1 inhibitor that inhibits FOXO-dependent glucose production devoid of lipogenic activity in hepatocytes. |
|
| DC23032 | OX-1 | A small molecule, specific Measles virus (MeV) entry inhibitor with IC50 of 55 uM. |
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| DC20659 | (2E,4E)-5-((1S,2S,4aR,6R,7S,8S,8aS)-7-hydroxy-2,6,8-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)-2-methyl-N-(pyridin-3-yl-methyl)penta-2,4-dienamide Featured | A small-molecule compound that disrupts the Golgi apparatus by inhibiting the activation of ADP-ribosylation factor 1 (ARF1). |
|
| DC21203 | KKL-40 | A small-molecule inhibitor of bacterial ribosome rescue that exhibits broad-spectrum antimicrobial activity against bacteria grown in liquid culture. |
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| DC22787 | EML-633 | A small-molecule inhibitor of Spindlin1 (SPIN1) with Kd of 2 uM. |
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| DC22788 | EML-631 | A small-molecule inhibitor of Spindlin1 (SPIN1) with Kd of 4 uM. |
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| DC22937 | STA-21 | A small-molecule inhibitor of STAT3. |
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| DC20558 | STOML3 inhibitor OB-1 Featured | OB-1 is a small-molecule inhibitor of STOML3 oligomerization that reverses pathological mechanical hypersensitivity in vivo; effectively inhibits the self-association of stomatin, STOML1 and STOML2 at 2 uM, but not podocin; reversibly reduces the sensitiv |
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| DC11752 | iKIX1 | A small-molecule inhibitor of the interaction of the C. glabrata Pdr1 activation domain with the C. glabrata Gal11A KIX domain with Ki of 18 uM. |
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| DC23027 | INP-0400 | A small-molecule inhibitor of type III secretion in Y. pseudotuberculosis, without affecting in vitro multiplication, causes a dose- and growth phase-dependent inhibition of C. trachomatis RB multiplication.. |
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| DC11759 | AKCI | A small-molecule inhibitor that blocks the Aurora C/IκBα interaction (IC50=24.9 uM) and exerts antitumor activity in MDA-MB-231 breast cancer cells. |
|
| DC22553 | KIN-1408 | A small-molecule MAVS-dependent IRF3 agonist that shows antiviral activity against Flaviviridae, Filoviridae (Ebola virus), Orthomyxoviridae (influenza A virus), Arenaviridae (Lassa virus) and Paramyxoviridae (RSVs, Nipah virus). |
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| DC11686 | (R)-CCX-777 | A small-molecule partial agonist of CXCR7 (ACKR3).. |
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| DC11687 | (S)-CCX-777 | A small-molecule partial agonist of CXCR7 (ACKR3).. |
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| DC11685 | CCX-777 | A small-molecule partial agonist of CXCR7 (ACKR3).. |
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| DC22799 | ML-162 Featured | A small-molecule probe that selectively kills cells induced to express mutant RAS. |
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| DC22800 | ML-210 Featured | A small-molecule probe that selectively kills cells induced to express mutant RAS. |
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| DC21029 | Fusicoccin-A | A small-molecule stabilizer of 14-3-3 protein-protein interactions that stabilizes the complex between 14-3-3 and the stress response regulator GCN1. |
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