| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC5078 | Tivozanib(AV-951) Featured | Tivozanib (AV-951, KRN-951) is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 0.21 nM/0.16 nM/0.24 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met EGFR and IGF-1R. |
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| DC8336 | Tizoxanide Featured | Tizoxanide is a potent inhibitor of hepatitis B virus and hepatitis C virus. |
|
| DC8736 | Tofacitinib Featured | Tofacitinib is a novel inhibitor of JAK3 with IC50 of 1 nM, 20- to 100-fold less potent versus JAK2 and JAK1. Phase 3. |
|
| DC5165 | Tofacitinib (CP-690550) Citrate Featured | Tofacitinib is a novel inhibitor of JAK3 with IC50 of 1 nM, 20- to 100-fold less potent versus JAK2 and JAK1. Phase 3. |
|
| DC7826 | Tofogliflozin hydrate | Tofogliflozin is an inhibitor of subtype 2 sodium-glucose transport protein (SGLT2). |
|
| DC8008 | TOK-001(Galeterone) Featured | TOK-001 is a multifunctional antiandrogen and CYP17 inhibitor(IC50=47 nM) in castration resistant prostate cancer (CRPC). |
|
| DC11485 | Tolcapone Featured | Tolcapone is an orally active catechol-O-methyltransferase (COMT) inhibitor. |
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| DC9148 | Tolvaptan Featured | Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation. |
|
| DC7519 | Torcetrapib Featured | Torcetrapib is a CETP inhibitor with IC50 of 37 nM, elevates HDL-C and reduces nonHDL-C in plasma. Phase 3. |
|
| DC9332 | Tozadenant | Tozadenant (SYN-115) is an adenosine A2A receptor antagonist. |
|
| DC8223 | TP-0903 Featured | TP-0903 is a a high-affinity Axl inhibitor with IC50 of 27 nM. |
|
| DC10611 | Trabectedin Featured | Trabectedin (Ecteinascidin-743 or ET-743) is a novel antitumour agent of marine origin with potent antitumour activity both in vitro and in vivo. |
|
| DC1099 | Trametinib Featured | Trametinib is a highly specific and potent MEK1 and MEK2 inhibitor with IC50 of 0.92 nM and 1.8 nM, respectively. |
|
| DC6400 | Tranilast (SB 252218) Featured | Tranilast (SB 252218) |
|
| DC8824 | Traxoprodil Featured | Traxoprodil is an NMDA ε 2 (NR2B) antagonist that has been studied as an alternative to serotonin selective reuptake inhibitors. |
|
| DC7522 | Triapine Featured | Triapine is a potent ribonucleotide reductase inhibitor with broad spectrum antitumor activity by inhibiting DNA synthesis. Phase 2. |
|
| DC21567 | Triazavirin (Riamilovir) Featured | Triazavirin is a guanine nucleotide analog antiviral originally developed in Russia that has shown efficacy against influenza A and B, including the H5N1 strain. It appears that Triazavirin has shown promise in reducing influenza disease severity and associated complications.5 Given the similarities between SARS-CoV-2 and H5N1, health officials are investigating Triazavirin as an option to combat SARS-CoV-2, the coronavirus responsible for COVID-19. |
|
| DC9157 | Trifluoperazine dihydrochloride | Trifluoperazine Dihydrochloride is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic. |
|
| DC12037 | Triptolide Featured | Triptolide is the major bioactive constituent of T. wilfordii Hook F., also known as thunder god vine, a traditional Chinese medicinal herb with known antiproliferative, immunosuppressive, anti-inflammatory, antifertility, and anti-polycystic kidney disea |
|
| DC9538 | TRO 19622 Featured | TRO19622, a small cholesterol-like molecule, is a neuroregenerative and neuroprotective compound. |
|
| DC11385 | Trofinetide(NNZ2566) Featured | Trofinetide (NNZ-2566) is an analog of a molecule which is derived from IGF-1 and occurs naturally in the brain. IGF-1 is a growth factor stimulated by growth hormone. |
|
| DC8903 | Troglitazone | Troglitazone(CS-045), PPARγ agonist, is an anti-diabetic thiazolidinedione (TZD) with anti-inflammatory and anti-tumor activity. |
|
| DC10737 | Tropifexor (LJN452) Featured | Tropifexor (LJN452) is a highly potent non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH). |
|
| DC10217 | TRx0237 (LMTX) mesylate Featured | TRx 0237 (LMTX™) mesylate is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia. |
|
| DC11087 | TRX-818 sodium | TRX-818 sodium (Foslinanib sodium ) is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities, induces cancer cell apoptosis and inhibits cancer cell proliferation. |
|
| DC8272 | U-104 Featured | U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM; low inhibition for CA I and CA II. |
|
| DC4133 | Udenafil | Udenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED) |
|
| DC10083 | UK-371804 Featured | UK-371804 is a potent and selective uPA inhibitor with excellent enzyme potency (Ki 10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin). |
|
| DC8153 | Umeclidinium bromide Featured | Umeclidinium bromide(GSK573719A) is a muscarinic receptor antagonist which is useful in treatment of chronic obstructive pulmonary disease (COPD). |
|
| DC10431 | Upadacitinib Featured | Upadacitinib (ABT-494) is a potent and selective Janus kinase (JAK) 1 inhibitor being developed for the treatment of several autoimmune disorders with an IC50 of 43 nM. |
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