| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC7699 | VTP-27999 Featured | VTP-27999 is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases. |
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| DC11844 | VTP-43742 | VTP-43742 (VTP43742) is a highly potent, selective, oral RORγt inverse agonist for the treatment of autoimmune disorders, including multiple sclerosis and psoriasis.. |
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| DC3106 | VX-680 (MK-0457,Tozasertib) Featured | VX-680 (MK-0457, Tozasertib) is a pan-Aurora inhibitor of Aurora A, Aurora B and Aurora C with Kiapp of 0.6 nM, 18 nM and 4.6 nM, respectively. |
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| DC1061 | VX-702 (VX702) Featured | VX-702 is a highly selective inhibitor of p38 MAPKα with IC50 of 4-20 nM. |
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| DC4173 | VX-745 Featured | VX-745 is a potent and selective inhibitor of p38α MAPK and p38β MAPK with IC50 of 10 nM and 220 nM, respectively. |
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| DC1059 | Lumacaftor(vx-809，vx809) Featured | VX-809 is a CFTR modulator with EC50 of 0.1 μM. |
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| DC7040 | WAY-362450 (XL335; Turofexorate isopropyl) Featured | WAY-362450 (XL335; Turofexorate isopropyl) is a highly potent, selective, and orally active farnesoid X receptor (FXR) agonist with an EC50 of 4 nM.WAY-362450 is useful for dyslipidemia. |
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| DC9498 | Xanomeline (oxalate) | Xanomeline(LY246708) is a selective M1 muscarinic receptor agonist. |
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| DC1097 | XL-184 (Cabozantinib,BMS907351) Featured | XL184 (Cabozantinib) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. |
|
| DC3129 | xl647 | XL647 is a novel spectrum-selective kinase inhibitor for EGFR, ErbB2, KDR, Flt-4 and EphB4 with IC50 of 0.3 nM, 16 nM, 1.5 nM, 8.7 nM and 1.4 nM, respectively. |
|
| DC4119 | YM155 Featured | YM155 is a potent IAP (inhibitor of apoptosis proteins) inhibitor for survivin with IC50 of 0.54 nM. |
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| DCAPI1015 | Zafirlukast(Accolate) | Zafirlukast(Accolate) |
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| DCAPI1063 | Zanamivir (Relenza) Featured | Zanamivir is an influenza viral neuraminidase inhibitor with IC50 values of 0.95 nM and 2.7 nM for influenza A and B, respectively. |
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| DC7753 | Zatebradine hydrochloride | Zatebradine hydrochloride is a bradycardic agent that creates use-dependent inhibition of hyperpolarization-activated current (If) in sinoatrial node cells (EC50 = 480 nM) and Purkinje fibres. |
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| DC9461 | Zatebradine | Zatebradine(UL-FS49) is a potent HCN channels antagonist, which decreased the heartbeat in a reversible manner; 92% inhibition of the hHCN1-mediated current at 10 uM. |
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| DC9490 | Zaurategrast | Zaurategrast(CDP-323) is an oral α4-integrin inhibitor. |
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| DC9435 | Zibotentan（ZD4054） Featured | Zibotentan (ZD4054) is an orally administered, potent and specific ETA-receptor (endothelin A receptor) antagonist (IC50 = 21 nM). |
|
| DCAPI1039 | Ziprasidone HCl | Ziprasidone HCl |
|
| DC9343 | ZLN024 (hydrochloride) | ZLN024 Hcl is a novel AMPK allosteric activator; activated α1β1γ1 and α2β1γ1 by around 2–2.5 fold with an EC50 of about 1–2 uM. IC50 value: 1-2 uM (EC50) [1] Target: AMPK activator ZLN024 activated AMPK in L6 myotubes and stimulated glucose uptake and |
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| DC1084 | ZM447439 (ZM-447439) Featured | ZM-447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. |
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| DC11277 | Zoliflodacin(AZD0914) Featured | Zoliflodacin (ETX0914;AZD0914) is a novel spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor. |
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| DC1077 | ZSTK474 Featured | ZSTK474 is a potent pan-class I PI3K inhibitor with IC50 of 37 nM. |
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| DC9113 | Ketanserin |
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| DC9178 | Ketanserin Tartrate |
|
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| DC9187 | Mosapride Citrate | Mosapride citrate is a gastroprokinetic agent that acts as a selective 5HT4 agonist. |
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| DC11075 | Amelparib |
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| DC10764 | Theliatinib (HMPL-309) Featured | Theliatinib (HMPL-309) is a novel small molecule, EGFR tyrosine kinase inhibitor with potential antineoplastic and anti-angiogenesis activities. |
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| DC10423 | Motixafortide(BKT140) Featured | Motixafortide (BKT140 4-fluorobenzoyl) is a novel CXCR4 antagonist with an IC50 vakue of ～1 nM. |
|
| DC10325 | Aviptadil Featured | Aviptadil (INN) is an analog of vasoactive intestinal polypeptide (VIP) for the treatment of erectile dysfunction,showed potent activity against COVID-19(SARS-COV-2). |
|
| DC7376 | BMS777607 Featured | BMS-777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50 of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM. |
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