Cat. No. | Product name | CAS No. |
DC9776 |
Pazopanib Hydrochloride
Featured
Pazopanib Hcl (GW-786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively. |
635702-64-6 |
DC2600 |
Pazopanib
Featured
Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR-α/β, and c-Kit. |
444731-52-6 |
DC11100 |
PBI-4050 sodium
PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively. |
1254472-97-3 |
DC11099 |
PBI-4050
PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively. |
1002101-19-0 |
DC9723 |
PBTZ169
Featured
PBTZ169 is a decaprenyl-phosphoribose-epimerase (DprE1) inhibitor. |
1377239-83-2 |
DC11770 |
PC786
Featured
PC786 (PC-786) is a potent non-nucleoside RSV L-protein polymerase inhibitor with IC50 of 2.1 nM and 0.5 nM in cell-free enzyme assay and mini-genome assay in HEp-2 cells, respectively. |
1902114-15-1 |
DC1106 |
PCI-32765 (Ibrutinib)
Featured
PCI-32765 (Ibrutinib) is a potent and highly selective Btk inhibitor with IC50 of 0.5 nM. |
936563-96-1 |
DC10531 |
PCO371
Featured
PCO371 is a novel, orally active small molecule that acts as a full agonist of PTHR1. |
1613373-33-3 |
DC7224 |
PD 123319
Featured
PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM. |
136676-91-0 |
DC1056 |
PD0325901 (Mirdametinib)
Featured
PD0325901 (PD325901) is selective and non ATP-competitive MEK inhibitor with IC50 of 0.33 nM. |
391210-10-9 |
DC8168 |
Peficitinib(ASP015K,JNJ-54781532)
Featured
Peficitinib(ASP015K,JNJ-54781532) is a novel potent JAK inhibitor, which demonstrated potent efficacy in adjuvant-induced arthritis model in rats. |
944118-01-8 |
DC7225 |
Pelitinib (EKB-569; WAY-EKB 569)
Featured
Pelitinib (EKB-569; WAY-EKB 569) is a potent irreversible EGFR inhibitor with IC50 of 38.5 nM. |
257933-82-7 |
DC11360 |
Pemafibrate
Featured
Pemafibrate is an orally bioavailable and selective agonist of peroxisome proliferator-activated receptor α (PPARα; EC50 = 1 nM for transcriptional activity), a transcription factor that is essential for regulation of lipid homeostasis. |
848259-27-8 |
DC8149 |
Pemetrexed disodium
Featured
Pemetrexed disodium is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively. |
150399-23-8 |
DCAPI1121 |
Peramivir
Peramivir |
229614-55-5 |
DCAPI1010 |
Peramivir Trihydrate
Featured
Peramivir, also known as BCX1812 and RWJ 270201, is an antiviral drug for the treatment of influenza. Peramivir is a neuraminidase inhibitor, acting as a transition-state analogue inhibitor of influenza neuraminidase and thereby preventing new viruses from emerging from infected cells. Peramivir was approved to treat influenza infection in adults. |
1041434-82-5 |
DC7226 |
Perampanel(E2007)
Featured
Perampanel(E2007; ER 155055-90) is a selective noncompetitive AMPA-type glutamate receptor antagonist which has demonstrated anticonvulsant activity in experimental seizure models and antiepileptic activity in clinical trials. |
380917-97-5 |
DC2021 |
Perifosine (KRX-0401)
Featured
Perifosine (KRX-0401) is a novel Akt inhibitor with IC50 of 4.7 μM. |
157716-52-4 |
DC10529 |
PF 05089771
Featured
PF 05089771 is a Nav1.7 channel blocker extracted from patent WO/2010/079443 A1, compound example 788, has an IC50 of 8.6 nM. |
1235403-62-9 |
DC8259 |
PF0477736
Featured
PF 477736 is a CHK inhitor with Ki values of 0.49 and 47 nM for Chk1 and Chk2 respectively. A proprietary compound targeting cell cycle checkpoint kinase 1 (chk1) with potential chemopotentiation activity |
952021-60-2 |
DC11664 |
PF-00446687 hydrochloride
PF-00446687 hydrochloride (PF-446687) is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 nM. |
862282-10-8 |
DC11665 |
PF-00446687
PF-00446687(PF-446687) is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 nM. |
862281-92-3 |