| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC6906 | Aprepitant (MK-0869, L-754030) Featured | Substance P antagonists (SPA). |
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| DC10581 | Succinobucol（AGI 1067) Featured | Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. |
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| DC9732 | Sufugolix(TAK-013) Featured | Sufugolix(TAK-013) is a non-peptide, orally-active, selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (IC50 = 0.1 and 0.06 nM for affinity and in vitro inhibition, respectively). |
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| DC3145 | Sunitinib base Featured | Sunitinib Malate (Sutent, SU11248) is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit. |
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| DCAPI1388 | Suplatast tosylate | Suplatast tosylate |
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| DC10733 | Sutezolid (PNU-100480) Featured | Sutezolid (PNU-100480) is an oxazolidinone antimicrobial being developed for the treatment of tuberculosis. |
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| DC5017 | Suvorexant Featured | Suvorexant (MK-4305) is a potent, selective, and orally bioavailable antagonist of OX1R and OX2R currently under clinical investigation as a novel therapy for insomnia.Suvorexant is an analytical reference standard categorized as a diazepane sedative.Formulations containing suvorexant show abuse potential similar to zolpidem in recreational polydrug users with a history of sedative and psychedelic drug use.2 Suvorexant is regulated as a Schedule IV compound in the United States. This product is intended for use in analytical forensic applications. |
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| DC8852 | SW-044248 Featured | SW-044248 is a Novel Inhibitor of Topoisomerase I Is Selectively Toxic for a Subset of Non-Small Cell Lung Cancer Cell Lines. |
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| DC8308 | SYM2206 | SYM2206 is a novel, potent, non-competitive AMPA receptor antagonist (IC50 = 2.8 μM ). |
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| DC5105 | Favipiravir (T-705) Featured | T 705(Favipiravir) is a RNA-directed RNA polymerase NS5B inhibitor.T 705(Favipiravir) is useful for Antiviral agents. |
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| DC9842 | T0901317 Featured | T0901317 is a potent, high affinity liver X receptor (LXR) agonist (EC50 ~ 50 nM, Kd values are 7 and 22 nM for LXR-α and LXR-β respectively). |
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| DC8024 | T-5224 Featured | T-5224 is a selective inhibitor of c-Fos/activator protein (AP)-1, attenuates lipopolysaccharide-induced liver injury in mice. |
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| DC5901 | Tadalafil Featured | Tadalafil is a potent and selective inhibitor of Phosphodiesterase-5 (PDE5) This compound prevents the breakdown of phosphodiesterases, many of which are used as secondary messengers. By preventing the breakdown of these messenger molecules, tadalafil can |
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| DC7945 | TAK-063 Featured | TAK-063 is a highly potent, selective and orally active PDE10A inhibitor with IC50 of 0.30 nM; >15000-fold selectivity over other PDEs. |
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| DC11208 | TAK-071 Featured | TAK-071 is a novel, potent and highly selective muscarinic acetylcholine receptor 1 (M1R) positive allosteric modulator. EC50 of TAK-071 M1R agonist activities is 520 nM. |
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| DC9311 | Serabelisib(TAK-117,INK1117,MLN1117) Featured | TAK-117(INK1117,MLN1117) is an orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha isoform with potential antineoplastic activity. |
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| DC11633 | TAK-243 Featured | TAK-243 (MLN-7243, AOB87172) is a small-molecule, cell-permeable inhibitor of ubiquitin-activating enzyme E1 (UAE1). |
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| DC7306 | TAK-438 Featured | TAK-438 is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. |
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| DC10523 | TAK-659 HCl Featured | TAK-659 hydrochloride is a potent, selective and orally available spleen tyrosine kinase (Syk) inhibitor with an IC50 of 3.2 nM. |
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| DC7304 | TAK 715 | TAK-715 is a p38 MAPK inhibitor for p38α with IC50 of 7.1 nM, 28-fold more selective for p38α over p38β, no inhibition to p38γ/δ, JNK1, ERK1, IKKβ, MEKK1 or TAK1. |
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| DC7308 | TAK-733 Featured | TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of 3.2 nM, inactive to Abl1, AKT3, c-RAF, CamK1, CDK2, c-Met, etc. |
|
| DC11397 | TAK-779 Featured | TAK-779 is a potent and selective nonpeptide antagonist of CCR5 and CXCR3, with a Ki of 1.1 nM for CCR5, and effectively and selectively inhibits R5 HIV-1, with EC50 and EC90 of 1.2 nM and 5.7 nM, respectively, in MAGI-CCR5 cells. |
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| DC5073 | TAK-875(Fasiglifam) Featured | TAK-875 is a potent, selective and orally bioavailable GPR40 agonist with EC50 of 0.072 μM. |
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| DC11370 | TAK-901 Featured | TAK-901 is a non-selective Aurora kinase inhibitor (IC50s = 3.1, 10, and 4.2 nM for Aurora A, B, and C, respectively). |
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| DC8739 | Talabostat mesylate | Talabostat mesilate(PT-100; Val-boroPro) is an orally active, specific inhibitor of dipeptidyl peptidases(IC50=1 nM for DPP4), including tumor-associated fibroblast activation protein. |
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| DC9180 | Tamoxifen Citrate Featured | Tamoxifen(ICI-46474) is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen,showed potent activity against COVID-19(SARS-COV-2) with EC50 MERS-COV(10.117), SARS-COV(11.696). |
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| DC7894 | Tandutinib(MLN518) | Tandutinib (MLN518, CT53518) is a potent FLT3 antagonist with IC50 of 0.22 μM, also inhibits PDGFR and c-Kit, 15 to 20-fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR and KDR. Phase 2. |
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| DC7769 | Tanomastat | Tanomastat is an angiogenesis and Matrix Metalloproteinase inhibitor |
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| DC4158 | Tranabant (MK-0364) | Taranabant is a highly selective cannabinoid-1 (CB1) receptor inverse agonist. |
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| DC1102 | Tariquidar (XR9576) Featured | Tariquidar (XR9576) is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 5.1 nM. |
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