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Therapeutic Antibodies

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Cat. No. Product Name Field of Application Chemical Structure
A423 Ezabenlimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Ezabenlimab (BI-754091) is an anti-PD-1 mAb with binding constant Kd value of 6 nM (CHO cells). Ezabenlimab blocks the interaction of PD-1 with PD-L1 and PD-L2. Ezabenlimab increases interferon-γ secretion in T cells, and inhibits tumor growth in vivo.
A424 Serplulimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Serplulimab (HLX 10) is humanized monoclonal anti-PD-1 antibody. Serplulimab can be used in research of small cell lung cancer.
A425 Penpulimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured Penpulimab is an IgG1 backbone anti-PD-1 monoclonal antibody with antitumor activities.
A426 Balstilimab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibod) Featured Balstilimab (AGEN2034) is a fully human monoclonal IgG4 antibody against PD-1.
A427 UCB patent anti-PD-1 Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody) Featured
A428 MOR-8457 Biosimilar(Anti-PDGFB Reference Antibody) Featured
A429 Thrombogenics patent anti-PDGF-C Biosimilar(Anti-PDGFC / VEGFE Reference Antibody) Featured
A430 Olaratumab Biosimilar(Anti-PDGFRA / CD140a Reference Antibody) Featured Olaratumab (IMC-3G3; LY3012207) is an anti-platelet-derived growth factor receptor alpha (PDGFRα) human monoclonal IgG1 antibody with antitumor activity.
A431 Tovetumab Biosimilar(Anti-PDGFRA / CD140a Reference Antibody) Featured Tovetumab (MEDI-575) is an anti-PDGFRα monoclonal antibody that selectively blocks the PDGFRα signal transduction. Tovetumab can be used in the research of glioblastoma and non-small cell lung cancer (NSCLC).
A432 IMC-2C5 Biosimilar(Anti-PDGFRB / CD140b Reference Antibody) Featured
A433 Novo Nordisk patent anti-PGLYRP1 Biosimilar(Anti-PGLYRP1 / PGRP-S Reference Antibody) Featured
A434 Bavituximab Biosimilar(Anti-Phosphatidylserine Reference Antibody) Featured Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a phosphatidylserine (PS)-targeting monoclonal antibody, suppresses tumor growth by targeting tumor vasculature and reactivating antitumor immunity. Bavituximab plus Paclitaxel (HY-B0015) and Carboplatin (HY-17393), have enhanced inhibition on non-small-cell lung cancer.
A435 ATH3G10 Biosimilar(Anti-Phosphorylcholine Reference Antibody) Featured
A436 Diaccurate patent anti-sPLA2-GIB Biosimilar(Anti-PLA2G1B Reference Antibody) Featured
A437 ATN-658 Biosimilar(Anti-PLAUR / uPAR / CD87 Reference Antibody) Featured
A438 Genentech anti-PMEL17 Biosimilar(Anti-PMEL Reference Antibody) Featured
A439 Novartis patent anti-PMEL17 Biosimilar(Anti-PMEL Reference Antibody) Featured
A440 Genentech patent anti-Polyubiquitin Biosimilar(Anti-Polyubiquitin Reference Antibody) Featured
A441 Eureka patent anti-PRAME Biosimilar(Anti-PRAME Reference Antibody) Featured
A442 BAY-1158061 Biosimilar(Anti-PRLR / Prolactin Receptor Reference Antibody) Featured
A443 Rolinsatamab Biosimilar(Anti-PRLR / Prolactin Receptor Reference Antibody) Featured Rolinsatamab is a IgG1κ type chimeric antibody targeting to PRLR (prolactin receptor). Rolinsatamab can be conjugated with pyrrolobenzodiazepine (PDB) dimer SGD-1882 (HY-101127) via a cleavable maleimidocaproyl type linker, to form an antibody-drug conjugate, Rolinsatamab talirine. One Rolinsatamab talirine has an average of 2 site-specific drug attachment engineered cysteines (C242, C242'). The linker equips the valine-alanine dipeptide, as cathepsine B cleavage site. on an average of 2 site-specific drug attachment engineered cysteines (C242, C242').
A444 Forerunner patent anti-Prominin-1 Biosimilar(Anti-PROM1 / CD133 Reference Antibody) Featured
A445 AGS-1C4D4 Biosimilar(Anti-PSCA Reference Antibody) Featured
A446 Inclacumab Biosimilar(Anti-P-Selectin / CD62p Reference Antibody) Featured Inclacumab (Anti-Human selectin P Recombinant Antibody) is a human monoclonal IgG4 antibody selectively targets P-selectin with a Kd value of 9.9 nM. Inclacumab inhibits P-selectin glycoprotein ligand 1 (PSGL-1) mimetic peptide bind with P-selectin with an IC50 value of 1.9 μg/mL and strongly inhibits cell adhesion.
A447 Neihulizumab Biosimilar(Anti-PSGL1 / CD162 Reference Antibody) Featured Neihulizumab (ALTB-168) is an immune checkpoint agonistic antibody that binds to human CD162 (PSGL-1), leading to downregulation of activated T-cells. Neihulizumab can be uesd for steroid-refractory acute graft-versus-host-disease (SR-aGVHD), psoriasis, psoriatic arthritis and ulcerative colitis research.
A448 AG02-ADC Biosimilar(Anti-PTGFRN / CD315 Reference Antibody) Featured
A121 Ocrelizumab Featured
A115 Casirivimab Biosimilar Featured Casirivimab (REGN10933) is a human monoclonal antibody that targets the SARS-CoV-2 virus, which causes COVID-19. Casirivimab is ineffective against COVID-19 variants. Casirivimab can be used in combination with Imdevimab (HY-P99342), which alters the lung response of K18-hACE2 mice to the SARS-CoV-2 δ variant, effectively reducing viral load and improving symptoms.
A108 L19-TNF Biosimilar(Anti-Fibronectin Reference Antibody) Featured
A120 Imdevimab Featured Imdevimab (REGN10987) is a human monoclonal antibody to target SARS-CoV-2 virus, which causes COVID-19. Imdevimab lacks efficacy against COVID-19 variants. Imdevimab can be used in combination with Casirivimab (HY-P99341), it reduces viral load and improves diseases.

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