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Therapeutic Antibodies

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Cat. No. Product Name Field of Application Chemical Structure
A118 Tezepelumab Featured Tezepelumab (anti-TSLP) is human monoclonal antibody (IgG2λ) that binds specifically to TSLP, blocking it from interacting with its heterodimeric receptor. Tezepelumab can be used for the research of severe, uncontrolled asthma.
A119 Aducanumab Featured Aducanumab (BIIB037) is a human monoclonal antibody that selectively targets aggregated amyloid-beta (Aβ). Aducanumab shows brain penetration, and can be used for Alzheimer's disease (AD) research.
A117 Lecanemab Featured Lecanemab (Mouse IGG2a) is a monoclonal antibody that targets soluble β-amyloid and has the potential to reduce cognitive decline. The variable region of Lecanemab (Mouse IGG2a) is consistent with that of Lecanemab, while the constant region is of Mouse IGG2a sequence. Lecanemab (Mouse IGG2a) holds promise for research in the field of Alzheimer's disease.
A113 Acapatamab Biosimilar Featured Acapatamab (AMG-160) is an anti-CD3E/FOLH1 monoclonal antibody.
A216 Anrukinzumab Biosimilar(Anti-IL-13 Reference Antibody) Featured Anrukinzumab (IMA-638) is a humanized anti-IL-13 monoclonal antibody. Anrukinzumab effectively reduces lung inflammation in a cynomolgus monkey model. Anrukinzumab can be used in studies of ulcerative colitis (UC) as well as asthma.
A293 BMS patent anti-Integrin α5β1 Biosimilar(Anti-Integrin a5b1 (ITGA5 & ITGB1) Reference Antibody) Featured
A379 Genentech patent anti-Notch3 Biosimilar(Anti-NOTCH3 Reference Antibody) Featured
A449 Cofetuzumab Biosimilar(Anti-PTK7 / CCK4 Reference Antibody) Featured Cofetuzumab (PF-06523435) is a humanized IgG1-κ monoclonal antibody targeting PTK7. The expression system of Cofetuzumab is usually CHO (Chinese Hamster Ovary) cells.
A450 Apamistamab Biosimilar(Anti-PTPRC / CD45 Reference Antibody) Featured
A451 Novartis patent anti-CD45 Featured
A452 Ntx1088 Biosimilar(Anti-PVR / CD155 Reference Antibody) Featured
A453 GSK-4381562 Biosimilar(Anti-PVRIG Reference Antibody) Featured
A454 COM701 Biosimilar(Anti-PVRIG Reference Antibody) Featured
A455 Foravirumab Biosimilar(Anti-Rabies virus GP Reference Antibody) Featured Foravirumab (CR4098) is a monoclonal antibody against rabies virus glycoprotein antigenic site III.
A456 Rafivirumab Biosimilar(Anti-Rabies virus GP Reference Antibody) Featured Rafivirumab (CR57) is an anti-rabies virus monoclonal antibody for the prophylaxis of rabies. Rafivirumab has neutralizing potency against a broad spectrum of RABV variants. Rafivirumab can be used for research of cocktails.
A457 Medella patent anti-RAMP-3 Biosimilar(Anti-RAMP3 Reference Antibody) Featured
A458 19G9 Biosimilar(Anti-RG1 Reference Antibody) Featured
A459 Elezanumab Biosimilar(Anti-RGMA Reference Antibody) Featured Elezanumab (ABT-555; AE12-1Y-QL) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa). Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway, with an IC50 around 97 pM. Elezanumab promotes neuroregeneration and neuroprotection in neuronal injury and demyelination models binds N-terminal RGMa, blocks BMP signaling and lacks RGMc cross-reactivity. elezanumab has neuroregenerative and neuroprotective activities without impact on iron metabolism.
A460 DISC-0974 Biosimilar(Anti-RGMC / HFE2 Reference Antibody) Featured
A461 Roledumab Biosimilar(Anti-RHD / CD240d Reference Antibody) Featured Roledumab (LFB-R593) is a human IgG1-κ antibody targeting RHD/CD240D. Roledumab is expressed by YB2/0 rat hybridoma cells.
A462 LFB Anti-RhD Biosimilar(Anti-RHD / CD240d Reference Antibody) Featured
A463 Asclepius Technology patent anti-Robo1 CAR Biosimilar(Anti-ROBO1 Reference Antibody) Featured
A464 Zilovertamab Biosimilar(Anti-ROR1 Reference Antibody) Featured Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling.
A465 Ozuriftamab Biosimilar(Anti-ROR2 Reference Antibody) Featured Ozuriftamab is a naked human IgG1 kappa antibody of receptor tyrosine kinase-like orphan receptor 2 ROR2, can be used to synthesis ADC.
A466 Oncomed patent anti-RSPO1 Biosimilar(Anti-RSPO1 Reference Antibody ) Featured
A467 Rosmantuzumab Biosimilar(Anti-RSPO3 Reference Antibody) Featured Rosmantuzumab (OMP-131R10) is an anti-R-spondin 3 (RSPO3) humanized monoclonal antibody. Rosmantuzumab can be used for the research of advanced telapsed and refractory solid tumors.
A468 Palivizumab Biosimilar(Anti-RSV-F Reference Antibody) Featured Palivizumab (MEDI 493) is a humanized monoclonal antibody against respiratory syncytial virus (RSV). Palivizumab can bind to RSV F protein with a Kd value of 1.4 nM. Palivizumab can prevent respiratory syncytial virus infection in cotton mice.
A469 Motavizumab Biosimilar(Anti-RSV-F Reference Antibody) Featured Motavizumab (MEDI-524) is an anti-human RSV (respiratory syncytial virus) monoclonal antibody. Motavizumab can be used in respiratory syncytial virus infection in high-risk infants research.
A470 Ozanezumab Biosimilar(Anti-RTN4 / NOGO Reference Antibody) Featured Ozanezumab (GSK1223249) is an anti-Nogo-A (neurite outgrowth inhibitor A) monoclonal antibody. Ozanezumab can be used in amyotrophic lateral sclerosis (ALS) and multiple sclerosis research.
A471 Atinumab Biosimilar(Anti-RTN4 / NOGO Reference Antibody) Featured Atinumab (6A3-IgG4) is an antibody. Teropavimab can be used for the research of spinal cord injury (SCI).

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