A118 |
Tezepelumab
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Tezepelumab (anti-TSLP) is human monoclonal antibody (IgG2λ) that binds specifically to TSLP, blocking it from interacting with its heterodimeric receptor. Tezepelumab can be used for the research of severe, uncontrolled asthma. |
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A119 |
Aducanumab
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Aducanumab (BIIB037) is a human monoclonal antibody that selectively targets aggregated amyloid-beta (Aβ). Aducanumab shows brain penetration, and can be used for Alzheimer's disease (AD) research. |
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A117 |
Lecanemab
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Lecanemab (Mouse IGG2a) is a monoclonal antibody that targets soluble β-amyloid and has the potential to reduce cognitive decline. The variable region of Lecanemab (Mouse IGG2a) is consistent with that of Lecanemab, while the constant region is of Mouse IGG2a sequence. Lecanemab (Mouse IGG2a) holds promise for research in the field of Alzheimer's disease. |
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A113 |
Acapatamab Biosimilar
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Acapatamab (AMG-160) is an anti-CD3E/FOLH1 monoclonal antibody. |
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A216 |
Anrukinzumab Biosimilar(Anti-IL-13 Reference Antibody)
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Anrukinzumab (IMA-638) is a humanized anti-IL-13 monoclonal antibody. Anrukinzumab effectively reduces lung inflammation in a cynomolgus monkey model. Anrukinzumab can be used in studies of ulcerative colitis (UC) as well as asthma. |
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A293 |
BMS patent anti-Integrin α5β1 Biosimilar(Anti-Integrin a5b1 (ITGA5 & ITGB1) Reference Antibody)
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A379 |
Genentech patent anti-Notch3 Biosimilar(Anti-NOTCH3 Reference Antibody)
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A449 |
Cofetuzumab Biosimilar(Anti-PTK7 / CCK4 Reference Antibody)
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Cofetuzumab (PF-06523435) is a humanized IgG1-κ monoclonal antibody targeting PTK7. The expression system of Cofetuzumab is usually CHO (Chinese Hamster Ovary) cells. |
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A450 |
Apamistamab Biosimilar(Anti-PTPRC / CD45 Reference Antibody)
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A451 |
Novartis patent anti-CD45
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A452 |
Ntx1088 Biosimilar(Anti-PVR / CD155 Reference Antibody)
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A453 |
GSK-4381562 Biosimilar(Anti-PVRIG Reference Antibody)
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A454 |
COM701 Biosimilar(Anti-PVRIG Reference Antibody)
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A455 |
Foravirumab Biosimilar(Anti-Rabies virus GP Reference Antibody)
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Foravirumab (CR4098) is a monoclonal antibody against rabies virus glycoprotein antigenic site III. |
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A456 |
Rafivirumab Biosimilar(Anti-Rabies virus GP Reference Antibody)
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Rafivirumab (CR57) is an anti-rabies virus monoclonal antibody for the prophylaxis of rabies. Rafivirumab has neutralizing potency against a broad spectrum of RABV variants. Rafivirumab can be used for research of cocktails. |
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A457 |
Medella patent anti-RAMP-3 Biosimilar(Anti-RAMP3 Reference Antibody)
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A458 |
19G9 Biosimilar(Anti-RG1 Reference Antibody)
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A459 |
Elezanumab Biosimilar(Anti-RGMA Reference Antibody)
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Elezanumab (ABT-555; AE12-1Y-QL) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa). Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway, with an IC50 around 97 pM. Elezanumab promotes neuroregeneration and neuroprotection in neuronal injury and demyelination models binds N-terminal RGMa, blocks BMP signaling and lacks RGMc cross-reactivity. elezanumab has neuroregenerative and neuroprotective activities without impact on iron metabolism. |
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A460 |
DISC-0974 Biosimilar(Anti-RGMC / HFE2 Reference Antibody)
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A461 |
Roledumab Biosimilar(Anti-RHD / CD240d Reference Antibody)
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Roledumab (LFB-R593) is a human IgG1-κ antibody targeting RHD/CD240D. Roledumab is expressed by YB2/0 rat hybridoma cells. |
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A462 |
LFB Anti-RhD Biosimilar(Anti-RHD / CD240d Reference Antibody)
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A463 |
Asclepius Technology patent anti-Robo1 CAR Biosimilar(Anti-ROBO1 Reference Antibody)
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A464 |
Zilovertamab Biosimilar(Anti-ROR1 Reference Antibody)
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Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling. |
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A465 |
Ozuriftamab Biosimilar(Anti-ROR2 Reference Antibody)
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Ozuriftamab is a naked human IgG1 kappa antibody of receptor tyrosine kinase-like orphan receptor 2 ROR2, can be used to synthesis ADC. |
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A466 |
Oncomed patent anti-RSPO1 Biosimilar(Anti-RSPO1 Reference Antibody )
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A467 |
Rosmantuzumab Biosimilar(Anti-RSPO3 Reference Antibody)
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Rosmantuzumab (OMP-131R10) is an anti-R-spondin 3 (RSPO3) humanized monoclonal antibody. Rosmantuzumab can be used for the research of advanced telapsed and refractory solid tumors. |
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A468 |
Palivizumab Biosimilar(Anti-RSV-F Reference Antibody)
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Palivizumab (MEDI 493) is a humanized monoclonal antibody against respiratory syncytial virus (RSV). Palivizumab can bind to RSV F protein with a Kd value of 1.4 nM. Palivizumab can prevent respiratory syncytial virus infection in cotton mice. |
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A469 |
Motavizumab Biosimilar(Anti-RSV-F Reference Antibody)
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Motavizumab (MEDI-524) is an anti-human RSV (respiratory syncytial virus) monoclonal antibody. Motavizumab can be used in respiratory syncytial virus infection in high-risk infants research. |
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A470 |
Ozanezumab Biosimilar(Anti-RTN4 / NOGO Reference Antibody)
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Ozanezumab (GSK1223249) is an anti-Nogo-A (neurite outgrowth inhibitor A) monoclonal antibody. Ozanezumab can be used in amyotrophic lateral sclerosis (ALS) and multiple sclerosis research. |
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A471 |
Atinumab Biosimilar(Anti-RTN4 / NOGO Reference Antibody)
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Atinumab (6A3-IgG4) is an antibody. Teropavimab can be used for the research of spinal cord injury (SCI). |
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