APG-1387
Cat. No.: DC42284
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Chemical Structure
1570231-89-8
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Field of application
APG-1387, a bivalent SMAC mimetic, is an IAP antagonist that can induce proteasomal degradation of IAPs. APG-1387 sensitizes immune-mediated cell apoptosis in cancers. APG-1387 can be used for the research of hepatocellular carcinoma, ovarian cancer, and nasopharyngeal carcinoma.
| Cas No.: |
1570231-89-8 |
| Chemical Name: |
APG-1387 |
| Synonyms: |
APG-1387, APG 1387l; APG1387; SM-1387; SM 1387; SM1387, dasminapant |
| SMILES: |
O=C(NC(C1=CC=CC=C1)C2=CC=CC=C2)[C@@H]3CC[C@H](CCN(S(C4=CC=CC(S(N(C[C@@H]5NC([C@H](C)NC)=O)CC[C@@H]6N([C@H](C(NC(C7=CC=CC=C7)C8=CC=CC=C8)=O)CC6)C5=O)(=O)=O)=C4)(=O)=O)C[C@@H]9NC([C@@H](NC)C)=O)N3C9=O |
| Formula: |
C60H72N10O10S2 |
| M.Wt: |
1157.4 |
| Purity: |
>98% |
| Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
MSDS
| TITLE |
DOWNLOAD |
| MSDS_25891_DC42284_1570231-89-8 |
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COA
| LOT NO. |
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